Results 11 to 20 of about 1,648,635 (304)
Background Vascular endothelial cell (EC) alignment in the direction of flow is an adaptive response that protects against aortic diseases, such as atherosclerosis. The Rho GTPases are known to regulate this alignment.
Angelina J. Lay +8 more
doaj +1 more source
Cross-Talk of NADPH Oxidases and Inflammation in Obesity
Obesity is a major risk factor for cardiovascular and metabolic diseases. Multiple experimental and clinical studies have shown increased oxidative stress and inflammation linked to obesity.
Henning Morawietz +6 more
doaj +1 more source
Vascular device interaction with the endothelium [PDF]
Copyright @ 2008 Elsevier. This is the post-print version of the article.Cerebral stents and Intra Aortic Balloon Pumps (IABP) are examples of mechanical devices that are inserted into arteries to restore flows to clinically healthy states. The stent and
Atherton, MA +4 more
core +2 more sources
The regulation of function of endothelial cell–cell junctions is fundamental in sustaining vascular integrity. The polycistronic microRNA (miR) complexes containing miR-23a-27a-24-2, and 23b-27b-24-1 are predicted to target the majority of major ...
Jia Li +6 more
doaj +1 more source
Microvascular alterations in hypertension and vascular aging [PDF]
Hypertension and aging are characterized by vascular remodelling and stiffness as well as endothelial dysfunction. Endothelial function declines with age, since aging is associated with senescence of the endothelium due to increased rate of apoptosis and
Battistoni, Allegra +5 more
core +1 more source
Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery [PDF]
<b>BACKGROUND AND PURPOSE</b> Anandamide and sphingosine-1-phosphate (S1P) both regulate vascular tone in a variety of vessels. This study aimed to examine the mechanisms involved in the regulation of coronary vascular tone by anandamide and ...
Alemany +47 more
core +2 more sources
Emerging Roles of Vascular Endothelium in Metabolic Homeostasis.
Our understanding of the role of the vascular endothelium has evolved over the past 2 decades, with the recognition that it is a dynamically regulated organ and that it plays a nodal role in a variety of physiological and pathological processes ...
Xinchun Pi, Liang Xie, C. Patterson
semanticscholar +1 more source
A polymer coated cicaprost-eluting stent increases neointima formation and impairs vessel function in the rabbit iliac artery [PDF]
Drug-eluting stents have been successful in reducing in-stent restenosis but are not suitable for all lesion types and have been implicated in causing late stent thrombosis due to incomplete regeneration of the endothelial cell layer.
Jones, Robert L. +4 more
core +2 more sources
Junctional Adhesion Molecule-C Mediates the Recruitment of Embryonic-Endothelial Progenitor Cells to the Perivascular Niche during Tumor Angiogenesis [PDF]
The homing of Endothelial Progenitor Cells (EPCs) to tumor angiogenic sites has been described as a multistep process, involving adhesion, migration, incorporation and sprouting, for which the underlying molecular and cellular mechanisms are yet to be ...
Bieback, Karen +6 more
core +1 more source
Tobacco smoking and hemodynamic forces are key stimuli in the development of endothelial dysfunction and atherosclerosis. High laminar flow has an atheroprotective effect on the endothelium and leads to a reduced response of endothelial cells to ...
Sindy Giebe +6 more
doaj +1 more source

