Results 11 to 20 of about 1,625,308 (345)

The vascular endothelium [PDF]

open access: yesAnales de la Facultad de Medicina, 2014
Over the last 40 years, research on the vascular endothelium has provided important clues for the understanding of vascular disease. This new knowledge is finding its way into clinical medicine.
Salvador Moncada
doaj   +5 more sources

Malaria and Vascular Endothelium

open access: yesArquivos Brasileiros de Cardiologia, 2014
Involvement of the cardiovascular system in patients with infectious and parasitic diseases can result from both intrinsic mechanisms of the disease and drug intervention.
Aristóteles Comte de Alencar Filho   +3 more
doaj   +7 more sources

Vascular device interaction with the endothelium [PDF]

open access: yesBiomedicine & Pharmacotherapy, 2008
Copyright @ 2008 Elsevier. This is the post-print version of the article.Cerebral stents and Intra Aortic Balloon Pumps (IABP) are examples of mechanical devices that are inserted into arteries to restore flows to clinically healthy states. The stent and
Atherton, MA   +4 more
core   +7 more sources

Nanomechanics of vascular endothelium [PDF]

open access: yesCell and Tissue Research, 2014
The mechanical characteristics of endothelial cells reveal four distinct compartments, namely glycocalyx, cell cortex, cytoplasm and nucleus. There is accumulating evidence that endothelial nanomechanics of these individual compartments control vascular ...
J. Fels   +4 more
semanticscholar   +4 more sources

The Vascular Endothelium and Human Diseases [PDF]

open access: yesInternational Journal of Biological Sciences, 2013
Alterations of endothelial cells and the vasculature play a central role in the pathogenesis of a broad spectrum of the most dreadful of human diseases, as endothelial cells have the key function of participating in the maintenance of patent and ...
P. Rajendran   +6 more
semanticscholar   +4 more sources

Vascular endothelium in diabetes. [PDF]

open access: yesAmerican Journal of Physiology-Renal Physiology, 2017
Three decades ago a revolutionary idea was born that ascribed to dysfunctional endothelia some manifestations of diabetes, the Steno hypothesis, so named after the Steno Diabetes Center, Gentofte, in Denmark. Here I briefly outline the accomplishments accrued in the past 15 years to buttress this hypothesis.
M. Goligorsky
semanticscholar   +4 more sources

Contributions of the Endothelium to Vascular Calcification [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Vascular calcification (VC) increases morbidity and mortality and constitutes a significant obstacle during percutaneous interventions and surgeries. On a cellular and molecular level, VC is a highly regulated process that involves abnormal cell transitions and osteogenic differentiation, re-purposing of signaling pathways normally used in bone, and ...
Li Zhang   +5 more
openaire   +6 more sources

Oxidative Stress, Antioxidants and Hypertension

open access: yesAntioxidants, 2023
As a major cause of morbidity and mortality globally, hypertension remains a serious threat to global public health. Despite the availability of many antihypertensive medications, several hypertensive individuals are resistant to standard treatments, and
Michael Amponsah-Offeh   +3 more
doaj   +1 more source

ARHGAP18: A Flow‐Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Vascular endothelial cell (EC) alignment in the direction of flow is an adaptive response that protects against aortic diseases, such as atherosclerosis. The Rho GTPases are known to regulate this alignment.
Angelina J. Lay   +8 more
doaj   +1 more source

Cross-Talk of NADPH Oxidases and Inflammation in Obesity

open access: yesAntioxidants, 2023
Obesity is a major risk factor for cardiovascular and metabolic diseases. Multiple experimental and clinical studies have shown increased oxidative stress and inflammation linked to obesity.
Henning Morawietz   +6 more
doaj   +1 more source

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