Results 11 to 20 of about 1,648,635 (304)

ARHGAP18: A Flow‐Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Vascular endothelial cell (EC) alignment in the direction of flow is an adaptive response that protects against aortic diseases, such as atherosclerosis. The Rho GTPases are known to regulate this alignment.
Angelina J. Lay   +8 more
doaj   +1 more source

Cross-Talk of NADPH Oxidases and Inflammation in Obesity

open access: yesAntioxidants, 2023
Obesity is a major risk factor for cardiovascular and metabolic diseases. Multiple experimental and clinical studies have shown increased oxidative stress and inflammation linked to obesity.
Henning Morawietz   +6 more
doaj   +1 more source

Vascular device interaction with the endothelium [PDF]

open access: yes, 2008
Copyright @ 2008 Elsevier. This is the post-print version of the article.Cerebral stents and Intra Aortic Balloon Pumps (IABP) are examples of mechanical devices that are inserted into arteries to restore flows to clinically healthy states. The stent and
Atherton, MA   +4 more
core   +2 more sources

The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b

open access: yesMolecular Therapy: Nucleic Acids, 2016
The regulation of function of endothelial cell–cell junctions is fundamental in sustaining vascular integrity. The polycistronic microRNA (miR) complexes containing miR-23a-27a-24-2, and 23b-27b-24-1 are predicted to target the majority of major ...
Jia Li   +6 more
doaj   +1 more source

Microvascular alterations in hypertension and vascular aging [PDF]

open access: yes, 2017
Hypertension and aging are characterized by vascular remodelling and stiffness as well as endothelial dysfunction. Endothelial function declines with age, since aging is associated with senescence of the endothelium due to increased rate of apoptosis and
Battistoni, Allegra   +5 more
core   +1 more source

Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery [PDF]

open access: yes, 2010
<b>BACKGROUND AND PURPOSE</b> Anandamide and sphingosine-1-phosphate (S1P) both regulate vascular tone in a variety of vessels. This study aimed to examine the mechanisms involved in the regulation of coronary vascular tone by anandamide and ...
Alemany   +47 more
core   +2 more sources

Emerging Roles of Vascular Endothelium in Metabolic Homeostasis.

open access: yesCirculation Research, 2018
Our understanding of the role of the vascular endothelium has evolved over the past 2 decades, with the recognition that it is a dynamically regulated organ and that it plays a nodal role in a variety of physiological and pathological processes ...
Xinchun Pi, Liang Xie, C. Patterson
semanticscholar   +1 more source

A polymer coated cicaprost-eluting stent increases neointima formation and impairs vessel function in the rabbit iliac artery [PDF]

open access: yes, 2016
Drug-eluting stents have been successful in reducing in-stent restenosis but are not suitable for all lesion types and have been implicated in causing late stent thrombosis due to incomplete regeneration of the endothelial cell layer.
Jones, Robert L.   +4 more
core   +2 more sources

Junctional Adhesion Molecule-C Mediates the Recruitment of Embryonic-Endothelial Progenitor Cells to the Perivascular Niche during Tumor Angiogenesis [PDF]

open access: yes, 2020
The homing of Endothelial Progenitor Cells (EPCs) to tumor angiogenic sites has been described as a multistep process, involving adhesion, migration, incorporation and sprouting, for which the underlying molecular and cellular mechanisms are yet to be ...
Bieback, Karen   +6 more
core   +1 more source

Cigarette smoke extract counteracts atheroprotective effects of high laminar flow on endothelial function

open access: yesRedox Biology, 2017
Tobacco smoking and hemodynamic forces are key stimuli in the development of endothelial dysfunction and atherosclerosis. High laminar flow has an atheroprotective effect on the endothelium and leads to a reduced response of endothelial cells to ...
Sindy Giebe   +6 more
doaj   +1 more source

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