Results 21 to 30 of about 183,947 (271)
Mathematical modeling of the vascular system [PDF]
In this article, we review the mathematical modeling for the vascular system.
arxiv +1 more source
Deciphering the relative contribution of vascular inflammation and blood rheology in metastatic spreading [PDF]
Vascular adhesion of circulating tumor cells (CTCs) is a key step in cancer spreading. If inflammation is recognized to favor the formation of vascular metastatic niches, little is known about the contribution of blood rheology to CTC deposition. Herein, a microfluidic chip, covered by a confluent monolayer of endothelial cells, is used for analyzing ...
arxiv +1 more source
Vascular endothelium in diabetes [PDF]
Three decades ago a revolutionary idea was born that ascribed to dysfunctional endothelia some manifestations of diabetes, the Steno hypothesis, so named after the Steno Diabetes Center, Gentofte, in Denmark. Here I briefly outline the accomplishments accrued in the past 15 years to buttress this hypothesis.
openaire +3 more sources
Vascular device interaction with the endothelium [PDF]
Cerebral stents and Intra Aortic Balloon Pumps (IABP) are examples of mechanical devices that are inserted into arteries to restore flows to clinically healthy states. The stent and the IABP ‘correct’ the arterial flow by static dilation and by cyclical occlusion respectively.
M. A. Atherton+4 more
openaire +5 more sources
The Vascular Endothelium and Human Diseases [PDF]
Alterations of endothelial cells and the vasculature play a central role in the pathogenesis of a broad spectrum of the most dreadful of human diseases, as endothelial cells have the key function of participating in the maintenance of patent and functional capillaries.
Gautam Sethi+6 more
openaire +3 more sources
Uncertainty quantification of a three-dimensional in-stent restenosis model with surrogate modelling [PDF]
In-Stent Restenosis is a recurrence of coronary artery narrowing due to vascular injury caused by balloon dilation and stent placement. It may lead to the relapse of angina symptoms or to an acute coronary syndrome. An uncertainty quantification of a model for In-Stent Restenosis with four uncertain parameters (endothelium regeneration time, the ...
arxiv
PAKing up to the endothelium [PDF]
Angiogenesis recapitulates the growth of blood vessels that progressively expand and remodel into a highly organized and stereotyped vascular network. During adulthood, endothelial cells that formed the vascular wall retain their plasticity and can be engaged in neo-vascularization in response to physiological stimuli, such as hypoxia, wound healing ...
arxiv +1 more source
Contribution of Oxidative Stress to Endothelial Dysfunction in Hypertension
Endothelial dysfunction is the hallmark of hypertension, which is a multifactorial disorder. In the cardiovascular system reactive oxygen species play a pivotal role in controlling the endothelial function and vascular tone.
Bruno Rodrigues Silva+2 more
doaj +1 more source
Organ-Specific Endothelial Dysfunction Following Total Body Irradiation Exposure
As the single cell lining of the heart and all blood vessels, the vascular endothelium serves a critical role in maintaining homeostasis via control of vascular tone, immune cell recruitment, and macromolecular transit.
Guru Prasad Sharma, Heather A. Himburg
doaj +1 more source
Cerebrovascular morphology in aging and disease -- imaging biomarkers for ischemic stroke and Alzheimers disease [PDF]
Background and Purpose: Altered brain vasculature is a key phenomenon in several neurologic disorders. This paper presents a quantitative assessment of vascular morphology in healthy and diseased adults including changes during aging and the anatomical variations in the Circle of Willis (CoW).
arxiv