Results 31 to 40 of about 1,648,635 (304)
The Vascular Endothelium and Human Diseases
International Journal on Biological Sciences, 2013 Alterations of endothelial cells and the vasculature play a central role in the pathogenesis of a broad spectrum of the most dreadful of human diseases, as endothelial cells have the key function of participating in the maintenance of patent and ...
P. Rajendran +6 more
semanticscholar +1 more source
Malaria and Vascular Endothelium
Arquivos Brasileiros de Cardiologia, 2014 Involvement of the cardiovascular system in patients with infectious and parasitic diseases can result from both intrinsic mechanisms of the disease and drug intervention.
Aristóteles Comte de Alencar Filho +3 more
doaj +1 more source
Journal of Pharmacological Sciences, 2011 .: Endothelium regulates vascular tone via release of endothelium-derived relaxing factors (EDRF) including nitric oxide (NO), prostaglandin I2 (PGI2), and endothelium-derived hyperpolarizing factor (EDHF).
Xin Jin +6 more
doaj +1 more source
Arteriogenesis versus angiogenesis: similarities and differences [PDF]
, 2007 Cardiovascular diseases account for more than half of total mortality before the age of 75 in industrialized countries. To develop therapies promoting the compensatory growth of blood vessels could be superior to palliative surgical surgical ...
Eitenmüller, Inka +3 more
core +1 more source
Endothelium-Derived Relaxing Factor–Mediated Vasodilation in Mouse Mesenteric Vascular Beds
Journal of Pharmacological Sciences, 2012 The endothelium in rat mesenteric vascular beds has been demonstrated to regulate vascular tone by releasing mainly endothelium-derived hyperpolarizing factor (EDHF), which is involved in the activation of K+ channels and gap-junctions.
Hiroki Fujiwara +7 more
doaj +1 more source
Organ-Specific Endothelial Dysfunction Following Total Body Irradiation Exposure
Toxics, 2022 As the single cell lining of the heart and all blood vessels, the vascular endothelium serves a critical role in maintaining homeostasis via control of vascular tone, immune cell recruitment, and macromolecular transit.
Guru Prasad Sharma, Heather A. Himburg
doaj +1 more source
Arterial pathology in canine mucopolysaccharidosis-I and response to therapy. [PDF]
, 2011 Mucopolysaccharidosis-I (MPS-I) is an inherited deficiency of α-L-iduronidase (IdU) that causes lysosomal accumulation of glycosaminoglycans (GAG) in a variety of parenchymal cell types and connective tissues.
Dickson, Patricia I +6 more
core +3 more sources
Contribution of Oxidative Stress to Endothelial Dysfunction in Hypertension
Frontiers in Physiology, 2012 Endothelial dysfunction is the hallmark of hypertension, which is a multifactorial disorder. In the cardiovascular system reactive oxygen species play a pivotal role in controlling the endothelial function and vascular tone.
Bruno Rodrigues Silva +2 more
doaj +1 more source
Uterine spiral artery remodeling involves endothelial apoptosis induced by extravillous trophoblasts through Fas/FasL interactions. [PDF]
, 2005 Objective— Invasion of uterine spiral arteries by extravillous trophoblasts in the first trimester of pregnancy results in loss of endothelial and musculoelastic layers.
Ashton, SV +6 more
core +1 more source
Hydrogen Peroxide Is an Endothelium-Derived Hyperpolarizing Factor in Animals and Humans
Journal of Pharmacological Sciences, 2003 Vascular endothelium plays an important role in maintaining vascular homeostasis by synthesizing and releasing several vasodilating factors, such as prostacyclin, nitric oxide (NO), and a yet unidentified endothelium-derived hyperpolarizing factor (EDHF).
Matoba Tetsuya, Hiroaki Shimokawa
doaj +1 more source