Results 21 to 30 of about 266,998 (298)
Endothelium in Diseased States [PDF]
BioMed Research International, 2014 Endothelium is the endocrine organ essential for maintenance of homeostasis in the entire body. Endothelium operates by a broad spectrum of signaling molecules controlling the contractile state of vascular smooth muscles and cardiomyocytes; long distance intercellular synchronization within the vascular wall; adhesive, coagulant, and rheological ...
Bernátová, Iveta +3 more
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Biology of the Endothelium [PDF]
Clinical Cardiology, 1997 The endothelium releases factors that control vascular relaxation and contraction, thrombogenesis and fibrinolysis, and platelet activation and inhibition. Maintaining the functional integrity of the endothelium, therefore, is critical for the preservation of blood flow and the prevention of thrombosis.
Thomas F. Lüscher, Matthias Barton
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Cell Transplantation, 2014 In human neonates, immature GABAergic interneurons are markedly affected by an excitotoxic insult. While in adults the interest of cell transplantation has been demonstrated in several neurological disorders, few data are available regarding the immature
Christian Roux +8 more
doaj +1 more source
Lipids and the endothelium [PDF]
Cardiovascular Research, 1999 The normal endothelium is characterised by the production of a number of molecules which affect the contractile state of adjacent myocytes and the behavior of formed elements within the blood stream, and by the absence of cell surface adhesion molecules. In addition, endothelial cells are important modulators of coagulation and fibrinolysis.
Jaye Chin-Dusting, Anthony M. Dart
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Endoglin: Beyond the Endothelium [PDF]
Biomolecules, 2020 Keywords: endoglin; CD105 TGF-β; BMP9; ALK-1; TRC105; tumor ...
Schoonderwoerd, M.J.A. +2 more
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Frontiers in Bioscience-Landmark, 2021 Tumour metastasis to the brain is a complex process involving crosstalk between the circulating tumour cells and the blood brain barrier (BBB). Astrocytes, which reside in the abluminal surface of the microvasculature of the BBB, are now known to play an
Layla Burn +4 more
doaj +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
AntioxidantsThe NADPH oxidase NOX4 that releases H2O2 can mediate vasoprotective mechanisms under pathophysiological conditions in conductive arteries. However, the role of NOX4 in resistance arteries and in perivascular adipose tissue is not well understood.
Patrick Diaba-Nuhoho +4 more
doaj +1 more source
Ivabradine and endothelium: an update [PDF]
Therapeutic Advances in Cardiovascular Disease, 2020 Ivabradine is a pure heart-rate lowering drug that is nowadays used, accordingly to the last ESC Guidelines, to reduce mortality and heart failure (HF) hospitalization in patients with HF with reduced ejection fraction and in symptomatic patiens with inappropriate sinus tachycardia.
Lucia Dallapellegrina +2 more
openaire +4 more sources