Redox Biology, 2017 Tobacco smoking and hemodynamic forces are key stimuli in the development of endothelial dysfunction and atherosclerosis. High laminar flow has an atheroprotective effect on the endothelium and leads to a reduced response of endothelial cells to ...
Sindy Giebe +6 more
doaj +1 more source
Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries [PDF]
, 2014 Transient receptor potential canonical type 3 (TRPC3) channels are non-selective cation channels and regulate intracellular Ca2+ concentration. We examined the role of TRPC3 channels in agonist-, membrane depolarization (high K+)-, and mechanical ...
Abramowitz, Joel +6 more
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Prosopis alba seed flour improves vascular function in a rabbit model of high fat diet-induced metabolic syndrome [PDF]
, 2019 Aims: Prosopis alba flour is a natural source of nutrient and phytochemicals with potential effects on cardiovascular risk factors. The aim of this work was to examine the effects of dietary supplementation with Prosopis alba seed flour (Pr-Feed) on a ...
Alarcón, Gabriela del Jesús +4 more
core +1 more source
Bench-to-bedside review: the role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury. [PDF]
, 2006 Activated protein C (APC) has emerged as a novel therapeutic agent for use in selected patients with severe sepsis, even though the mechanism of its benefit is not well established.
Looney, Mark R, Matthay, Michael A
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Exercise training and losartan improve endothelial function in heart failure rats by different mechanisms [PDF]
, 2013 Objectives. To investigate the mechanisms of losartan- and exercise training-induced improvements on endothelial dysfunction in heart failure. Design. Sprague-Dawley rats subjected to left coronary artery ligation inducing myocardial infarction and heart
Crozier I +5 more
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Drug treatment of hypertension: focus on vascular health [PDF]
, 2016 Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C. +2 more
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Neurobiology of Disease, 2012 In industrialized countries, cerebral palsy affects 2.5‰ of preterm and term infants. At a neurochemical level, the massive release of glutamate constitutes a major process leading to excitotoxicity and neonatal brain lesions. Previous studies, conducted
Faiza El Ghazi +13 more
doaj +1 more source
The role of endocardial endothelium in the effect of histamine on myocardial contractions of histamine H1 and H2 receptor blockade [PDF]
Praxis Medica, 2016 Endocardial endothelium (EE) is a barrier which controls the passage of macromolecules and fluids between the blood and the adjacent miocardial interstitium. At the same time it is the place of synthesis of numerous endothelial mediators. Histamine as an
Smiljić Sonja +4 more
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Diagnosis and management of iridocorneal endothelial syndrome [PDF]
, 2015 The iridocorneal endothelial (ICE) syndrome is a rare ocular disorder that includes a group of conditions characterized by structural and proliferative abnormalities of the corneal endothelium, the anterior chamber angle, and the iris.
Ambrosio, Oriella +5 more
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Neurobiology of Disease, 2013 Glutamate excitotoxicity is a consolidated hypothesis in neonatal brain injuries and tissue plasminogen activator (t-PA) participates in the processes through proteolytic and receptor mediated effects.
Vincent Jean Henry +11 more
doaj +1 more source