Rotaflip: A New CNN Layer for Regularization and Rotational Invariance in Medical Images [PDF]
arXiv, 2021 Regularization in convolutional neural networks (CNNs) is usually addressed with dropout layers. However, dropout is sometimes detrimental in the convolutional part of a CNN as it simply sets to zero a percentage of pixels in the feature maps, adding unrepresentative examples during training. Here, we propose a CNN layer that performs regularization by
arxiv
Robust Control of Nanoscale Drug Delivery System in Atherosclerosis: A Mathematical Approach [PDF]
arXiv, 2021 This paper proposes a mathematical approach for robust control of a nanoscale drug delivery system in treatment of atherosclerosis. First, a new nonlinear lumped model is introduced for mass transport in the arterial wall, and its accuracy is evaluated in comparison with the original distributed-parameter model.
arxiv
Simulation of Molecular Signaling in Blood Vessels: Software Design and Application to Atherogenesis [PDF]
Nano Communication Networks Vol.4, No.3, September 2013, 2013 This paper presents a software platform, named BiNS2, able to simulate diffusion-based molecular communications with drift inside blood vessels. The contribution of the paper is twofold. First a detailed description of the simulator is given, under the software engineering point of view, by highlighting the innovations and optimizations introduced ...
arxiv +1 more source
Modelling realistic 3D deformations of simple epithelia in dynamic homeostasis [PDF]
arXiv, 2022 The maintenance of tissue and organ structures during dynamic homeostasis is often not well understood. In order for a system to be stable, cell renewal, cell migration and cell death must be finely balanced. Moreover, a tissue's shape must remain relatively unchanged.
arxiv
Elongated Physiological Structure Segmentation via Spatial and Scale Uncertainty-aware Network [PDF]
arXiv, 2023 Robust and accurate segmentation for elongated physiological structures is challenging, especially in the ambiguous region, such as the corneal endothelium microscope image with uneven illumination or the fundus image with disease interference. In this paper, we present a spatial and scale uncertainty-aware network (SSU-Net) that fully uses both ...
arxiv
Computational modeling of in-stent restenosis: Pharmacokinetic and pharmacodynamic evaluation [PDF]
arXiv, 2023 Persistence of the pathology of in-stent restenosis even with the advent of drug-eluting stents warrants the development of highly resolved in silico models. These computational models assist in gaining insights into the transient biochemical and cellular mechanisms involved and thereby optimize the stent implantation parameters.
arxiv
Misrepair mechanism in the development of atherosclerotic plaques [PDF]
arXiv, 2015 Atherosclerosis is a disease characterized by the development of atherosclerotic plaques (APs) in arterial endothelium. The APs in part of an arterial wall are inhomogeneous on size and on distribution. In order to understand this in-homogeneity, the pathology of APs is analyzed by Misrepair mechanism, a mechanism proposed in our Misrepair-accumulation
arxiv
In vivo imaging of human cornea with high-speed and high-resolution Fourier-domain full-field optical coherence tomography [PDF]
arXiv, 2020 Corneal evaluation in ophthalmology necessitates cellular-resolution and fast imaging techniques allowing accurate diagnoses. Currently, the fastest volumetric imaging technique is Fourier-domain full-field optical coherence tomography (FD-FF-OCT) that uses a fast camera and a rapidly tunable laser source.
arxiv
Mathematical model for blood flow autoregulation by endothelium-derived relaxing factor [PDF]
arXiv, 2006 The fluid shear stress is an important regulator of the cardiovascular system via the endothelium-derived relaxing factor (EDRF) that is Nitric Oxide. This mechanism involves biochemical reactions in an arterial wall. The autoregulation process is managed by the vascular tonus and gives the negative feedback for the shear stress changing.
arxiv
P2X1 receptors and the endothelium [PDF]
Memórias do Instituto Oswaldo Cruz, 2005 Adenosine triphosphate (ATP) is now established as a principle vaso-active mediator in the vasculature. Its actions on arteries are complex, and are mediated by the P2X and P2Y receptor families. It is generally accepted that ATP induces a bi-phasic response in arteries, inducing contraction via the P2X and P2Y receptors on the smooth muscle cells, and
L. S. Harrington, J. A. Mitchell
openaire +5 more sources