Results 91 to 100 of about 2,705,124 (338)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The effect of ivermectin on the viral load and culture viability in early treatment of nonhospitalized patients with mild COVID-19 – a double-blind, randomized placebo-controlled trial

International Journal of Infectious Diseases, 2022
Objectives: Ivermectin, an antiparasitic agent, also has antiviral properties. In this study, we aimed to assess whether ivermectin has anti-SARS-CoV-2 activity.
Asaf Biber, Geva Harmelin, Dana Lev, Li Ram, Amit Shaham, Ital Nemet, Limor Kliker, Oran Erster, Michal Mandelboim, Eli Schwartz   +9 more
doaj   +1 more source

Measurement of masses in the [Formula: see text] system by kinematic endpoints in pp collisions at [Formula: see text]. [PDF]

, 2013
A simultaneous measurement of the top-quark, W-boson, and neutrino masses is reported for [Formula: see text] events selected in the dilepton final state from a data sample corresponding to an integrated luminosity of 5.0 fb-1 collected by the CMS ...
Adam, W, Adler, V, Alderweireldt, S, Bansal, M, Bansal, S, Basegmez, S, Beernaert, K, Benucci, L, Bergauer, T, Blekman, F, Blyweert, S, Bruno, G, Castello, R, Caudron, A, Ceard, L, Chatrchyan, S, Cimmino, A, Clerbaux, B, CMS Collaboration, Cornelis, T, Costantini, S, D'Hondt, J, De Lentdecker, G, De Wolf, EA, Dildick, S, Dragicevic, M, Erö, J, Fabjan, C, Friedl, M, Frühwirth, R, Garcia, G, Gay, APR, Ghete, VM, Hreus, T, Hrubec, J, Hörmann, N, Janssen, X, Jeitler, M, Kalogeropoulos, A, Keaveney, J, Khachatryan, V, Kiesenhofer, W, Klein, B, Knutsson, A, Knünz, V, Krammer, M, Krätschmer, I, Lellouch, J, Liko, D, Luyckx, S, Léonard, A, Maes, M, Marage, PE, Marinov, A, Mccartin, J, Mikulec, I, Mohammadi, A, Mossolov, V, Mucibello, L, Ocampo Rios, AA, Ochesanu, S, Olbrechts, A, Rabady, D, Rahbaran, B, Reis, T, Rohringer, C, Rohringer, H, Roland, B, Rougny, R, Ryckbosch, D, Schöfbeck, R, Shumeiko, N, Sigamani, M, Sirunyan, AM, Strauss, J, Strobbe, N, Suarez Gonzalez, J, Taurok, A, Tavernier, S, Thomas, L, Thyssen, F, Treberer-Treberspurg, W, Tumasyan, A, Tytgat, M, Van Doninck, W, Van Haevermaet, H, Van Mechelen, P, Van Mulders, P, Van Onsem, GP, Van Remortel, N, Van Spilbeeck, A, Vander Velde, C, Vanlaer, P, Villella, I, Walsh, S, Waltenberger, W, Wang, J, Wulz, C-E, Yazgan, E, Zaganidis, N   +99 more
core  

On the Determination of $|V_{ub}|$ from Inclusive Semileptonic Decay Spectra

, 1993
We propose a model independent method to determine $|V_{ub}|$ from the energy spectrum of the charged lepton in inclusive semileptonic $B$ decays. The method includes perturbative QCD corrections as well as nonperturbative ones.Comment: LaTeX, 19 pages ...
A. Ali, A. Falk, A. Falk, A. Manohar, B. Blok, B. Blok, B. Blok, Boris Blok, G. Altarelli, G. Corbo, G. Korchemsky, I. Bigi, I. Bigi, I. Bigi, I. Bigi, I. Bigi, I. Bigi, J. Chay, M. Jezabek, M. Neubert, M. Neubert, N. Cabibbo, P. Ball, T. Mannel, T. Mannel, Thomas Mannel   +25 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Challenges in translating end points from trials to observational cohort studies in oncology

Clinical Epidemiology, 2016
Anne Gulbech Ording,1 Deirdre Cronin-Fenton,1 Vera Ehrenstein,1 Timothy L Lash,1,2 John Acquavella,1 Mikael Rørth,1 Henrik Toft Sørensen1 1Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; 2Department of&
Ording AG, Cronin-Fenton D, Ehrenstein V, Lash TL, Acquavella J, Rørth M, Sørensen HT   +6 more
doaj  

Body weight algorithm predicts humane endpoint in an intracranial rat glioma model

Scientific Reports, 2020
Humane endpoint determination is fundamental in animal experimentation. Despite commonly accepted endpoint criteria for intracranial tumour models (20% body weight loss and deteriorated clinical score) some animals still die before being euthanized in ...
S. Helgers, S. Talbot, Ann-Kristin Riedesel, Laura Wassermann, Zhiqun Wu, J. Krauss, C. Häger, A. Bleich, K. Schwabe   +8 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

IDENTIFICATION OF ASCORBIC ACID CONTENT IN Carica papaya L. USING IODIMETRY AND UV-VIS SPECTROPHOTOMETRY

Indonesian Journal of Medical Laboratory Science and Technology, 2019
Ascorbic acid mostly comes from vegetables and fruits, especially fresh fruits. Vitamin C is a vitamin that can be formed by several types of plants. One of them is papaya which has various contents including vitamin C that can increase endurance, help ...
Nosy Maria Riscahyani, Evy Ratnasari Ekawati, Khoirul Ngibad   +2 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source