Results 11 to 20 of about 981,494 (350)
Adipose tissue is a major component for the regulation of energy homeostasis by storage and release of lipids. As a core element of RNA‐induced silencing complex, argonaute2 (Ago2) plays critical role in maintenance of systemic metabolic demand. Here, we
Hansi Zhang +7 more
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Adipocytes as regulators of energy balance and glucose homeostasis
Evan D. Rosen, Bruce M. Spiegelman
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Adiponectin and energy homeostasis [PDF]
White adipose tissue (WAT) is the premier energy depot. Since the discovery of the hormonal properties of adipose-secreted proteins such as leptin and adiponectin, WAT has been classified as an endocrine organ. Although many regulatory effects of the adipocyte-derived hormones on various biological systems have been identified, maintaining systemic ...
Bonggi, Lee, Jianhua, Shao
openaire +2 more sources
Mechanisms Driving Palmitate-Mediated Neuronal Dysregulation in the Hypothalamus
The hypothalamus maintains whole-body homeostasis by integrating information from circulating hormones, nutrients and signaling molecules. Distinct neuronal subpopulations that express and secrete unique neuropeptides execute the individual functions of ...
Calvin V. Lieu +2 more
doaj +1 more source
Macrophage depletion disrupts immune balance and energy homeostasis. [PDF]
Increased macrophage infiltration in tissues including white adipose tissue and skeletal muscle has been recognized as a pro-inflammatory factor that impairs insulin sensitivity in obesity.
Feng, Gen-Sheng +4 more
core +6 more sources
Neuronal control of energy homeostasis [PDF]
Neuronal control of body energy homeostasis is the key mechanism by which animals and humans regulate their long‐term energy balance. Various hypothalamic neuronal circuits (which include the hypothalamic melanocortin, midbrain dopamine reward and caudal brainstem autonomic feeding systems) control energy intake and expenditure to maintain body weight ...
Gao, Qian, Horvath, Tamas L.
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Neuronal cilia in energy homeostasis
A subset of genetic disorders termed ciliopathies are associated with obesity. The mechanisms behind cilia dysfunction and altered energy homeostasis in these syndromes are complex and likely involve deficits in both development and adult homeostasis. Interestingly, several cilia-associated gene mutations also lead to morbid obesity.
Kathryn M. Brewer +5 more
openaire +4 more sources
Astrocytes, emerging stars of energy homeostasis
Astrocytes have historically been considered structural supporting cells for neurons. Thanks to new molecular tools, allowing specific cell ablation or over-expression of genes, new unexpected astrocytic functions have recently been unveiled. This review
Simonetta Camandola
doaj +1 more source
Ginger Water Reduces Body Weight Gain and Improves Energy Expenditure in Rats
Obesity is a serious global problem that causes predisposition to numerous serious diseases. The current study aims to investigate the effect of ginger water on body weight and energy expenditure through modulation of mRNA expression of carbohydrate and ...
Samy Sayed +7 more
doaj +1 more source
A neuronal relay mediates a nutrient responsive gut/fat body axis regulating energy homeostasis in adult Drosophila [PDF]
The control of systemic metabolic homeostasis involves complex inter-tissue programs that coordinate energy production, storage, and consumption, to maintain organismal fitness upon environmental challenges.
Bauer, Christin +8 more
core +1 more source

