Results 41 to 50 of about 8,363,489 (262)
Energy Metabolism Decline in the Aging Brain—Pathogenesis of Neurodegenerative Disorders
Metabolites, 2020 There is a growing body of evidencethat indicates that the aging of the brain results from the decline of energy metabolism. In particular, the neuronal metabolism of glucose declines steadily, resulting in a growing deficit of adenosine triphosphate ...
Janusz W. Błaszczyk
semanticscholar +1 more source
Cancer Biology & MedicineObjective: Lung cancer is the leading cause of cancer-related deaths worldwide. Chemotherapy is associated with side effects, such as damage to myeloid cells and a reduction in the number of immune cells in patients.
Shumeng Lin +7 more
doaj +1 more source
Lactate and Myocardiac Energy Metabolism
Frontiers in Physiology, 2021 The myocardium is capable of utilizing different energy substrates, which is referred to as “metabolic flexibility.” This process assures ATP production from fatty acids, glucose, lactate, amino acids, and ketones, in the face of varying metabolic ...
Shuohui Dong +8 more
doaj +1 more source
Altered metabolism in cancer: insights into energy pathways and therapeutic targets
Molecular CancerCancer cells undergo significant metabolic reprogramming to support their rapid growth and survival. This study examines important metabolic pathways like glycolysis, oxidative phosphorylation, glutaminolysis, and lipid metabolism, focusing on how they ...
Muhammad Tufail, Canhua Jiang, Ning Li
semanticscholar +1 more source
NPY-mediated synaptic plasticity in the extended amygdala prioritizes feeding during starvation
Nature CommunicationsEfficient control of feeding behavior requires the coordinated adjustment of complex motivational and affective neurocircuits. Neuropeptides from energy-sensing hypothalamic neurons are potent feeding modulators, but how these endogenous signals shape ...
Stephan Dodt +7 more
doaj +1 more source
Evaluation of ruminal fermentation of ensiled fruit byproducts and their potential for feed use [PDF]
Asian-Australasian Journal of Animal Sciences, 2019 Objective Ensiling of tannin-rich fruit byproducts (FB) involves quantitative and qualitative changes in the tannins, which would consequently change the rumen fermentation characteristics.
Shimaa A Mousa +5 more
doaj +1 more source
Oligodendroglial Energy Metabolism and (re)Myelination
Life, 2021 Central nervous system (CNS) myelin has a crucial role in accelerating the propagation of action potentials and providing trophic support to the axons. Defective myelination and lack of myelin regeneration following demyelination can both lead to axonal ...
Vanja Tepavčević
doaj +1 more source
The World Journal of Men's Health, 2021 Aging is strongly related to energy metabolism, but the underlying processes and mechanisms are complex and incompletely understood. Restricting energy intake and reducing metabolic rate can slow the rate of aging and extend longevity, implying a ...
Andrzej Bartke +4 more
doaj +1 more source
Brain Regulation of Energy Metabolism [PDF]
Endocrinology and Metabolism, 2016 In healthy individuals, energy intake is in balance with energy expenditure, which helps to maintain a normal body weight. The brain's inability to control energy homeostasis underlies the pathology of hyperphagia and obesity.
Eun Roh, Min-Seon Kim
doaj +1 more source
Brain Sciences, 2023 26RFa, also referred to as QRFP, is a hypothalamic neuropeptide mainly known for its role in the regulation of appetite and glucose metabolism. Its possible relevance to emotional regulation is largely unexplored.
Henning Værøy +5 more
doaj +1 more source