Results 41 to 50 of about 8,934,147 (357)

Inhibition of Col6a5 Improve Lipid Metabolism Disorder in Dihydrotestosterone-Induced Hyperandrogenic Mice

open access: yesFrontiers in Cell and Developmental Biology, 2021
Hyperandrogenism is a key pathological feature of polycystic ovarian syndrome (PCOS). Excess androgen can lead to PCOS-like cell hypertrophy in the ovaries and adipose tissue of rodents.
Li-Feng Sun   +15 more
doaj   +1 more source

Thermal effects on cephalopod energy metabolism - A case study for Sepia officinalis [PDF]

open access: yes, 2008
Cephalopods are the largest, most active invertebrates and there is considerable evidence for their convergent evolution with fishes. However, most active cephalopods display standard and active metabolic rates that are several-fold higher than ...
Bock, C.   +5 more
core   +1 more source

Bioactivity in Whey Proteins Influencing Energy Balance [PDF]

open access: yes, 2012
Peer-reviewedObesity develops due to energy (food) intake exceeding energy expenditure. Nutrients that reduce the positive energy balance are thus being considered as therapies to combat obesity.
Cotter, Paul D.   +4 more
core   +1 more source

CircECE1 activates energy metabolism in osteosarcoma by stabilizing c-Myc

open access: yesMolecular Cancer, 2020
Background Osteosarcoma (OS) is the most common malignant bone tumor and has a poor prognosis. The potential involvement of circular RNAs (circRNAs) in OS progression remains unexplored.
Shuying Shen   +5 more
semanticscholar   +1 more source

Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. [PDF]

open access: yes, 2016
Expression of the oncogenic transcription factor MYC is disproportionately elevated in triple-negative breast cancer (TNBC), as compared to estrogen receptor-, progesterone receptor- or human epidermal growth factor 2 receptor-positive (RP) breast cancer.
Anderton, Brittany   +11 more
core   +1 more source

Role of Inositols and Inositol Phosphates in Energy Metabolism

open access: yesMolecules, 2020
Recently, inositols, especially myo-inositol and inositol hexakisphosphate, also known as phytic acid or IP6, with their biological activities received much attention for their role in multiple health beneficial effects.
Saimai Chatree   +4 more
semanticscholar   +1 more source

A naturally occurring polyacetylene isolated from carrots promotes health and delays signatures of aging

open access: yesNature Communications, 2023
To ameliorate or even prevent signatures of aging in ultimately humans, we here report the identification of a previously undescribed polyacetylene contained in the root of carrots (Daucus carota), hereafter named isofalcarintriol, which we reveal as ...
Carolin Thomas   +9 more
doaj   +1 more source

Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]

open access: yes, 2018
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz   +431 more
core   +2 more sources

Energy Metabolism Decline in the Aging Brain—Pathogenesis of Neurodegenerative Disorders

open access: yesMetabolites, 2020
There is a growing body of evidencethat indicates that the aging of the brain results from the decline of energy metabolism. In particular, the neuronal metabolism of glucose declines steadily, resulting in a growing deficit of adenosine triphosphate ...
Janusz W. Błaszczyk
semanticscholar   +1 more source

Activation of AMP-activated protein kinase by metformin induces protein acetylation in prostate and ovarian cancer cells [PDF]

open access: yes, 2016
AMP-activated protein kinase (AMPK) is an energy sensor and master regulator of metabolism. AMPK functions as a fuel gauge monitoring systemic and cellular energy status.
Galdieri, Luciano   +3 more
core   +2 more sources

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