Results 11 to 20 of about 4,215 (171)

Characterizing circadian rest-activity rhythm patterns across Alzheimer's disease continuum in Down syndrome. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Sleep and circadian rest–activity rhythm (RAR) disruption may bidirectionally relate to Alzheimer's disease (AD). Down syndrome (DS), the most common genetic cause of AD, presents sleep disorders, yet RAR patterns across the DS‐associated AD continuum remain uncharacterized. METHODS We analyzed 7‐day wrist actigraphy in 140 adults
Giménez S, Vaqué-Alcázar L, Clos S, Benejam B, Carmona-Iragui M, Maure-Blesa L, Videla L, Zhu N, Altuna M, Arranz J, Barroeta I, Rodríguez-Baz Í, Bejanin A, Bueno A, Fernandez S, Del Hoyo Soriano L, Pertierra L, Alcolea D, Miller B, Grinberg LT, Ruiz J, Lisgaras CP, Wu HT, Lleó A, Osorio RS, Blessing EM, Fortea J.   +26 more
europepmc   +2 more sources

Peak width of skeletonized mean diffusivity reveals early and multifactorial white matter injury across sporadic and Down syndrome-associated Alzheimer's disease. [PDF]

Alzheimers Dement
Abstract INTRODUCTION This study investigates the evolution with disease progression and pathological correlates of peak width of skeletonized mean diffusivity (PSMD), a sensitive diffusion magnetic resonance imaging (MRI) marker of microvascular white matter (WM) injury, in sporadic Alzheimer's disease (sAD) and Down syndrome (DS)–associated AD (DSAD).
Morcillo-Nieto AO, Franquesa-Mullerat M, Zsadanyi SE, Arriola-Infante JE, Vaqué-Alcázar L, Rozalem-Aranha M, Parra JA, Zhao Z, Arranz J, Rodríguez-Baz Í, Maure-Blesa L, Videla L, Barroeta I, Del Hoyo Soriano L, Benejam B, Fernández S, Sanjuan Hernandez A, Pertierra L, Giménez S, Santos-Santos M, Dols-Icardo O, Illán-Gala I, Alcolea D, Belbin O, Lleó A, Carmona-Iragui M, Fortea J, Bejanin A.   +27 more
europepmc   +2 more sources

Trastornos circadianos del sueño y enfermedades neurodegenerativas

Kranion, 2022
El envejecimiento conlleva una serie de cambios moleculares en el núcleo supraquiasmático (NSQ) que reducen la amplitud del ritmo circadiano. Esto, sumado a la reducción de la exposición a los sincronizadores externos, reduce la sincronía del ritmo ...
Laura Lillo Triguero
doaj   +1 more source

Reply #1 to: Glycemic Choreoballism

Tremor and Other Hyperkinetic Movements, 2016
This Author Reply Letter was written in response to a Letter to the Editor:Lee D, Ahn T. Glycemic choreoballism. Tremor Other Hyperkinet Mov. 2016; 6. doi: 10.7916/D8QJ7HNFThe Letter to the Editor, above, was written in response to these two Case ...
Carlos Cosentino, Luis Torres, Yesenia Nuñez, Rafael Suarez, Miriam Velez, Martha Flores   +5 more
doaj   +1 more source

Bilateral Hypertrophic Olivary Degeneration and Holmes Tremor without Palatal Tremor: An Unusual Association

Tremor and Other Hyperkinetic Movements, 2016
Background: Lesions in the Guillain–Mollaret triangle or dentate-rubro-olivary pathway may lead to hypertrophic olivary degeneration (HOD), a secondary trans-synaptic degeneration of the inferior olivary nucleus.
Carlos Cosentino, Miriam Velez, Yesenia Nuñez, Henry Palomino, Darko Quispe, Martha Flores, Luis Torres   +6 more
doaj   +1 more source

Absence of CX3CR1 impairs the internalization of Tau by microglia

Molecular Neurodegeneration, 2017
Background Extracellular Tau is toxic for neighboring cells, and it contributes to the progression of AD. The CX3CL1/CX3CR1 axis is an important neuron/microglia communication mechanism.
Marta Bolós, María Llorens-Martín, Juan Ramón Perea, Jerónimo Jurado-Arjona, Alberto Rábano, Félix Hernández, Jesús Avila   +6 more
doaj   +1 more source

Relevancia del metabolismo del folato en el contexto de enfermedades neurodegenerativas

Revista Habanera de Ciencias Médicas, 2021
Introducción: Varias enfermedades neurodegenerativas están asociadas a alteraciones en el metabolismo del folato, lo que tiene sustanciales implicaciones fisiopatológicas, clínicas y terapéuticas potenciales.
Yasnay Jorge Saínz, Dany Cuello Almarales, Luis Enrique Almaguer Mederos   +2 more
doaj  

ENFERMEDADES NEURODEGENERATIVAS; ASPECTOS NUTRICIONALES

NUTRICION HOSPITALARIA, 2015
Introduction: neurodegenerative diseases cause changes in the level of consciousness or swallowing mechanisms that often necessitate a specialized nutritional support. Objective: review the risk of malnutrition and its treatment in patients with cerebral vascular disease, Parkinson’s disease, dementia and amyotrophic lateral sclerosis ...
Luis, Daniel A. de, Izaola, Olatz, Fuente, Beatriz de la, Muñoz-Calero, Paloma, Franco-Lopez, Angeles   +4 more
openaire   +4 more sources

Relationship between the type and side of motor symptoms with the prevalence of non-motor symptoms in Parkinson's disease

Neurología (English Edition), 2011
Introduction: The relationship between laterality and asymmetry of Parkinson's disease and non-motor dysfunction has been studied mainly from the perspective of cognitive functions, and the few studies that have included other symptoms have mixed reports.
M. Rodríguez-Violante, A. Cervantes-Arriaga, A. Villar-Velarde, T. Corona   +3 more
doaj   +1 more source

Relación entre el tipo y lado de inicio de la sintomatología motora con la frecuencia de síntomas no motores en la enfermedad de Parkinson

Neurología, 2011
Resumen: Introducción: la relación de la lateralidad y asimetría de la enfermedad de Parkinson con la sintomatología de disfunción no motora ha sido abordada principalmente desde el punto de vista de las funciones cognitivas, y los escasos estudios que ...
M. Rodríguez-Violante, A. Cervantes-Arriaga, A. Villar-Velarde, T. Corona   +3 more
doaj   +1 more source