Results 41 to 50 of about 19,000 (208)

Acortamiento de telómeros en enfermedades neurodegenerativas: implicaciones terapéuticas

Revista Habanera de Ciencias Médicas, 2020
Introducción: Varias enfermedades neurodegenerativas están asociadas a la ocurrencia de acortamiento de los telómeros, convirtiéndolos en biomarcadores y dianas terapéuticas potenciales. Objetivo: Reflejar la relevancia del acortamiento de los telómeros
Geanny Sánchez Ochoa, Danny Cuello Almarales, Luis Enrique Almaguer Mederos   +2 more
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Síntomas no motores y motores en la enfermedad de Parkinson y su relación con la calidad de vida y los distintos subgrupos clínicos

Neurología, 2016
Resumen: Objetivos: El objetivo del presente trabajo es contrastar la influencia que presentan los síntomas motores y no motores en la calidad de vida de los pacientes con enfermedad de Parkinson (EP), y observar la asociación entre ambos tipos de ...
K. Berganzo, B. Tijero, A. González-Eizaguirre, J. Somme, E. Lezcano, I. Gabilondo, M. Fernandez, J.J. Zarranz, J.C. Gómez-Esteban   +8 more
doaj   +1 more source

Estudio sobre las enfermedades neurodegenerativas en España y su impacto económico y social [PDF]

, 2016
Depto. de Sociología: Metodología y TeoríaFac.
Arroyo Menéndez, Millán, Crespo Puras, María del Carmen, Finkel Morgenstern, Lucila, Garcés, Mario   +3 more
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Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

British Journal of Pharmacology, EarlyView.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda, Marcos M. Villegas‐Rojas, Isaac Pérez‐Segura, Maricela Espino‐Cambrón, Daniel Martinez‐Fong, Luis O. Soto‐Rojas   +5 more
wiley   +1 more source

Medicamentos quirales empleados en enfermedades neurodegenerativas: Alzheimer y Parkinson [PDF]

, 2011
66 p.La demencia es una patología que corresponde a un trastorno de las capacidades cognitivas, que se acompaña de alteraciones conductuales y de disminución de la autonomía, Es por esto la importancia de conocer y entender dos importantes enfermedades ...
Aravena Sepúlveda, Cristofer, Silva Santos, Leonardo (Prof. Guía)   +1 more
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Motor and non-motor symptoms of Parkinson's disease and their impact on quality of life and on different clinical subgroups

Neurología (English Edition), 2016
Introduction: The aim of the present study is to analyse the influence that motor and non-motor symptoms have on the quality of life (QoL) of patients with Parkinson's disease (PD), and to study the relationship between the two types of symptoms ...
K. Berganzo, B. Tijero, A. González-Eizaguirre, J. Somme, E. Lezcano, I. Gabilondo, M. Fernandez, J.J. Zarranz, J.C. Gómez-Esteban   +8 more
doaj   +1 more source

Clinical Outcome Assessments in Parkinson's Disease: A Scoping Review of Current Rating Scales and Future Needs

Movement Disorders Clinical Practice, Volume 13, Issue 5, Page 1124-1146, May 2026.
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma, Panagiota Tsitsi, Nirosen Vijiaratnam, Camila Aquino, Stephen R. Duma, Norbert Kovacs, Kigocha Lameck Okeng'o, Aparna Wagle Shukla, Roongroj Bhidayasiri, Tiago A. Mestre, Alvaro Sanchez Ferro, Alberto J. Espay, Michelle H.S. Tosin, Matej Skorvanek, Ioanna Markaki   +14 more
wiley   +1 more source

GSK-3 mouse models to study neuronal apoptosis

Frontiers in Molecular Neuroscience, 2011
Increased GSK-3 activity is believed to contribute to the etiology of chronic disorders like Alzheimer’s disease, schizophrenia, diabetes and some types of cancer, thus supporting therapeutic potential of GSK-3 inhibitors.
Raquel eGomez-Sintes, Raquel eGomez-Sintes, Felix eHernandez, Felix eHernandez, Jose J Lucas, Jose J Lucas, Jesus eAvila, Jesus eAvila   +7 more
doaj   +1 more source

Complementary and Integrative Medicine for the Treatment of Tourette's Syndrome

Movement Disorders Clinical Practice, Volume 13, Issue 5, Page 1166-1179, May 2026.
Abstract Background There is widespread interest in complementary and integrative medicine (CIM) among people with Tourette's syndrome (TS). Objective To perform a systematic review of evidence on the use of CIM to reduce tics and improve tic‐related quality of life.
Tamara Pringsheim, Catherine Deans, Saar Anis, Poonam Bhatia, Kevin Black, Yildiz Degirmenci, Donald Gilbert, Andreas Hartmann, Mariam Hull, Irene Malaty, Davide Martino, Alex Medina Escobar, Pablo Mir, Christelle Nilles, Marianna Sarchioto, Jibrin Sammani Usman, Harini Sarva, Katarzyna Smilowksa, Natalia Szejko, Kinga Tomczak, Daniel van Wamelen, Yulia Worbe   +21 more
wiley   +1 more source

Neurobanco del grupo de Neurociencias de Antioquia

Iatreia, 2005
El material biológico procedente de personas afectadas por enfermedades neurodegenerativas y el de controles sanos, es una necesidad para la investigación de las enfermedades neurodegenerativas.
Francisco Javier Lopera Restrepo, Amanda Saldarriaga, Diego Sepúlveda, Carlos A. Villegas, Gloria García   +4 more
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