Results 51 to 60 of about 4,215 (171)

Development and functional adaptation of intestinal macrophages across the lifespan

Clinical &Translational Immunology, Volume 15, Issue 6, 2026.
This article discusses intestinal macrophage development, including the influence of developmental origins and life stages; ontogeny and functional heterogeneity; preclinical and clinical evidence. Abstract Macrophages of the gastrointestinal system are central regulators of gut development, homeostasis and disease, yet their origin, functional ...
Baha Mustafa, Elisa L Hill‐Yardin, Sarah J Spencer   +2 more
wiley   +1 more source

Age-dependent progression from clearance to vulnerability in the early response of periventricular microglia to α-synuclein toxic species

Molecular Neurodegeneration
Cytoplasmic alpha-synuclein (αSyn) aggregates are a typical feature of Parkinson’s disease (PD). Extracellular insoluble αSyn can induce pathology in healthy neurons suggesting that PD neurodegeneration may spread through cell-to-cell transfer of αSyn ...
Mª Salomé Sirerol-Piquer, Ana Perez-Villalba, Pere Duart-Abadia, Germán Belenguer, Ulises Gómez-Pinedo, Laura Blasco-Chamarro, Pau Carrillo-Barberà, Azucena Pérez-Cañamás, Victoria Navarro-Garrido, Benjamin Dehay, Miquel Vila, Javier Vitorica, Francisco Pérez-Sánchez, Isabel Fariñas   +13 more
doaj   +1 more source

Factores asociados a la calidad de vida de sujetos con enfermedad de Parkinson y a la carga en el cuidador

Neurología, 2015
Resumen: Introducción: La enfermedad de Parkinson impacta en la calidad de vida del sujeto que la presenta, pero también ocasiona una carga para el cuidador.
M. Rodríguez-Violante, A. Camacho-Ordoñez, A. Cervantes-Arriaga, P. González-Latapí, S. Velázquez-Osuna   +4 more
doaj   +1 more source

Enfermedades neurodegenerativas: Alzehimer-Parquinson

, 2021
Antes de comenzar con la descripción del Síndrome de Alzheimer y la enfermedad de Parkinson,debemos mencionar algunas generalidades comunes a las enfermedades neurodegenerativas.Estas son un grupo de enfermedades que afectan al sistema nervioso central, siendo doscaracterísticas importantes la naturaleza degenerativa y el curso crónico de las mismas ...
openaire   +1 more source

Recommendations for genetic counseling for individuals at risk of autosomal dominant Alzheimer's disease in Latin America

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract Autosomal dominant Alzheimer's disease (ADAD) represents a small but impactful subset of Alzheimer's cases. Asymptomatic individuals at genetic risk face substantial personal and family implications when considering predictive testing for known familial variants.
Daniel A. Jiménez, Pablo M. Bagnati, Rosa Elena Flores‐Montes, María Laura Fernández, Angélica Zuno‐Reyes, David Aguillon, Carmen Alaez‐Verson, Luis E. Becerra‐Solano, María Isabel Behrens, Kelly Branda, Patricio Chrem, Nilton Custodio, Whitney Ducaine, Sofia Dumois‐Petersen, Luis Figuera, Marisol Londoño Castaño, Erika Mariana Longoria, Esmeralda Matute, Victor Sánchez, Andrea Slachevsky, Ana Luisa Sosa, Ezequiel Surace, Leonel Takada, Lauren Yaeger, Ellen Ziegemeier, Jorge J Llibre Guerra, for the Programa de asesoramiento genético en América Latina (PRAGA)   +26 more
wiley   +1 more source

Factors associated with the quality of life of subjects with Parkinson's disease and burden on their caregivers

Neurología (English Edition), 2015
Introduction: Parkinson's disease affects the quality of life of the individual with the disease in addition to creating a burden on the caregiver. Factors related to these effects include motor and non-motor aspects of the disease, as well as traits ...
M. Rodríguez-Violante, A. Camacho-Ordoñez, A. Cervantes-Arriaga, P. González-Latapí, S. Velázquez-Osuna   +4 more
doaj   +1 more source

Dieta mediterránea y dieta japonesa vs enfermedades neurodegenerativas

Journal of Negative and No Positive Results, 2020
Resumen Las enfermedades neurodegenerativas como la enfermedad de Alzheimer (EA) han cobrado gran importancia en los últimos años debido al aumento del número de casos a nivel mundial, convirtiéndose en un gran problema para la Salud Pública. Esto se ha debido a un incremento de la esperanza de vida, lo que se traduce en un mayor número de personas ...
Hu Yang, Yaxin, Iglesias López, María Teresa   +1 more
openaire   +3 more sources

Clinical Outcome Assessments in Parkinson's Disease: A Scoping Review of Current Rating Scales and Future Needs

Movement Disorders Clinical Practice, Volume 13, Issue 5, Page 1124-1146, May 2026.
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma, Panagiota Tsitsi, Nirosen Vijiaratnam, Camila Aquino, Stephen R. Duma, Norbert Kovacs, Kigocha Lameck Okeng'o, Aparna Wagle Shukla, Roongroj Bhidayasiri, Tiago A. Mestre, Alvaro Sanchez Ferro, Alberto J. Espay, Michelle H.S. Tosin, Matej Skorvanek, Ioanna Markaki   +14 more
wiley   +1 more source

Alzheimer’s disease as an inflammatory disease

Biomolecular Concepts, 2017
Alzheimer’s disease (AD) is a neurodegenerative condition characterized by the formation of amyloid-β plaques, aggregated and hyperphosphorylated tau protein, activated microglia and neuronal cell death, ultimately leading to progressive dementia.
Bolós Marta, Perea Juan Ramón, Avila Jesús   +2 more
doaj   +1 more source

Complementary and Integrative Medicine for the Treatment of Tourette's Syndrome

Movement Disorders Clinical Practice, Volume 13, Issue 5, Page 1166-1179, May 2026.
Abstract Background There is widespread interest in complementary and integrative medicine (CIM) among people with Tourette's syndrome (TS). Objective To perform a systematic review of evidence on the use of CIM to reduce tics and improve tic‐related quality of life.
Tamara Pringsheim, Catherine Deans, Saar Anis, Poonam Bhatia, Kevin Black, Yildiz Degirmenci, Donald Gilbert, Andreas Hartmann, Mariam Hull, Irene Malaty, Davide Martino, Alex Medina Escobar, Pablo Mir, Christelle Nilles, Marianna Sarchioto, Jibrin Sammani Usman, Harini Sarva, Katarzyna Smilowksa, Natalia Szejko, Kinga Tomczak, Daniel van Wamelen, Yulia Worbe   +21 more
wiley   +1 more source