Results 61 to 70 of about 19,000 (208)
Epilepsia Open, Volume 11, Issue 2, Page 577-591, April 2026.Abstract Objective Sialidosis type I (ST‐1) is an autosomal‐recessive, very rare, progressive lysosomal storage disorder caused by pathogenic variants in NEU1. It is clinically characterized by progressive ataxia, myoclonic seizures (MS), bilateral tonic–clonic seizures (BTCS), and distinctive ophthalmological findings.
Janina Gburek‐Augustat +15 more
wiley +1 more source
El Parkinson no me detiene campaña de concientización de la enfermedad de Parkinson [PDF]
, 2017 Parkinson's Disease, after Alzheimer’s, is the second most common neurodegenerative disorder to appear. This disease is commonly associated with people from 65 years or older, however, recent studies have revealed the existence of Juvenile Parkinson’s ...
Cedeño Estrella, Nicole Magaly +1 more
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Herpesvirus genome integration in whole‐genome sequences of dementia and control cohorts
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION The infectious hypothesis suggests that microbes like herpesviruses may play a role in the pathogenesis of Alzheimer's disease (AD) and other related dementias through methods that may include viral genome integration. The occurrence of herpesvirus genome integration in dementia patients has not been thoroughly characterized ...
Stacey L. Piotrowski +27 more
wiley +1 more source
Papel de la microglía en la patogenia de enfermedades neurodegenerativas [PDF]
, 2019 La microglía son las células del sistema nervioso central encargadas del mantenimiento de la inmunidad innata, las respuestas de defensa y la correcta conexión sináptica y, por lo tanto, su normal funcionamiento conduce a una ...
Hernández González, Sara
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In vivo mapping of cortical amyloid beta‐myelin coupling in preclinical Alzheimer's disease
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION Accumulating evidence suggests that amyloid‐β (Aβ) preferentially deposits in poorly myelinated cortical regions and may interfere with remyelination. We hypothesized that this vulnerability would manifest as altered Aβ–myelin coupling in preclinical Alzheimer's disease (AD).
Mercedes Atienza, Jose L. Cantero
wiley +1 more source
Molecular NeurodegenerationCytoplasmic alpha-synuclein (αSyn) aggregates are a typical feature of Parkinson’s disease (PD). Extracellular insoluble αSyn can induce pathology in healthy neurons suggesting that PD neurodegeneration may spread through cell-to-cell transfer of αSyn ...
Mª Salomé Sirerol-Piquer +13 more
doaj +1 more source
Neurología, 2015 Resumen: Introducción: La enfermedad de Parkinson impacta en la calidad de vida del sujeto que la presenta, pero también ocasiona una carga para el cuidador.
M. Rodríguez-Violante +4 more
doaj +1 more source
Terapia celular antiparkinsoniana con cuerpo carotídeo [PDF]
, 2015 Mini Workshop y mesa redondaLa terapia celular es una terapia avanzada en la que las células pueden ser usadas como auténticos medicamentos. Como elemento esencial de la medicina regenerativa, el objetivo principal de estas terapias es la sustitución de ...
Toledo, Juan José
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Wake‐promoting neuromodulators in Alzheimer's disease: Implications for sleep and brain clearance
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Neuromodulatory subcortical systems (NSS) regulate arousal, cognition, and sleep–wake transitions through widespread influence on cortical and subcortical networks. Increasing evidence links dysfunction of these systems to the pathogenesis of Alzheimer's disease (AD). Degeneration and dysregulation of NSS occurs during the preclinical phase of
Taylor J. Pedersen +7 more
wiley +1 more source
The landscape of dementia research, diagnosis, treatment, and care in Latin America
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Latin America is undergoing rapid population aging alongside a rising burden of dementia. While the region holds substantial potential for dementia risk reduction, challenges remain, such as delayed diagnoses, limited access to specialized care and biomarker testing, persistent stigma, and deep‐rooted structural inequities.
Claudia K. Suemoto +41 more
wiley +1 more source