Results 71 to 80 of about 56,688 (228)

Congenital heart defects in the Valencian Region 2007–2014: The population-based registry of congenital anomalies

open access: yesAnales de Pediatría (English Edition), 2020
Introduction: Congenital heart defects (CHDs) are the most prevalent and severe type of major congenital anomalies (CAs). The objective of this study was to determine the frequency and distribution of CHDs in the Valencian Region from 2007 to 2014 ...
María Pastor-García   +4 more
doaj   +1 more source

Screening of Synergic Interactions of Anti-Angiogenic and Anti-Tumor Compounds [PDF]

open access: yes, 2015
Solid cancers have several common characteristics that Hanahan & Weinberg named as the hallmarks of cancer. Angiogenesis is an essential hallmark of cancer because tumor cells need oxygen and nutrients delivered by the vascular system.
García-Vilas García, Javier Alejandro   +2 more
core  

Fraternidad política y enfermedades raras

open access: yesAraucaria, 2021
sumen Las enfermedades raras reciben, en general, menos financiación para su investigación y tratamientos médicos que el resto de enfermedades. Al margen de explicaciones científicas y económicas conocidas, existen dos grandes posiciones éticas respecto a este hecho, la que lo aprueba por razones de ética utilitarista, y la que lo condena insistiendo ...
openaire   +5 more sources

Age‐specific melanoma risk associated with nevi: a pooled analysis from the M‐SKIP project

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Objective This study investigates the association of melanoma risk with total‐body nevus count and the presence of atypical nevi in younger (< 40 years) and older (> 60 years) individuals. Methods A pooled analysis was conducted within the M‐SKIP project, based on multiple melanoma case‐control studies.
Giulia Doi   +20 more
wiley   +1 more source

Evaluation of metabolism and biosignaling in the angiogenic microenvironment as potential targets for therapeutic intervention [PDF]

open access: yes, 2017
The "re-discovery" of Warburg effect at the turn of the present millennium has been a key determinant of the current renewed interest on cancer metabolism. In fact, metabolic reprogramming has been identified as one of the hallmarks of cancer.
Carrillo, Paloma   +7 more
core  

Edge Effect on the Distribution of the Green Shield Bug Palomena prasina in Hazelnut Orchards, and the Role of Adjacent Habitats in Crop Colonization

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
Spring–Summer spatial dynamics of Palomena prasina (L.) and potential IPM strategies. ABSTRACT Palomena prasina (L.) (Hemiptera: Pentatomidae), the green shield bug (GSB), is an important hazelnut pest in Southern Europe. Currently, its control focuses on insecticide spraying during the crop season. We hypothesized that, as for other pentatomid species,
Laetitia Driss   +4 more
wiley   +1 more source

Clinical and genetic characterization of patients with eye diseases included in the Spanish Rare Diseases Patient Registry

open access: yesOrphanet Journal of Rare Diseases
Background The low prevalence of rare diseases poses a significant challenge in advancing their understanding. This study aims to delineate the clinical and genetic characteristics of patients with rare eye diseases (RED) enrolled in the Spanish Rare ...
Alberto Lopez-de la Rosa   +6 more
doaj   +1 more source

Gene expression analysis method integration and co-expression module detection applied to rare glucide metabolism disorders using ExpHunterSuite

open access: yesScientific Reports, 2021
High-throughput gene expression analysis is widely used. However, analysis is not straightforward. Multiple approaches should be applied and methods to combine their results implemented and investigated.
Fernando M. Jabato   +9 more
doaj   +1 more source

Interplay between glucose and palmitate uptake in breast carcinoma in vitro [PDF]

open access: yes, 2018
One of the most studied tumor cells lines in vitro is the breast carcinoma MDA-MB-231 cell line. Several studies have proved its glycolytic profile, namely known as the Warburg effect.
Carrillo, Paloma   +4 more
core  

AI‐assisted basal cell carcinoma diagnosis with LC‐OCT: A multicentric retrospective study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Real‐time AI assistance significantly improves dermatologists' performance in diagnosing basal cell carcinoma with LC‐OCT, outperforming traditional imaging methods. AI‐assisted novices reached expert‐level performance, bridging a 2‐year expertise gap, thus supporting a broader clinical adoption of non‐invasive technologies, reducing the need for ...
Sébastien Fischman   +64 more
wiley   +1 more source

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