Results 21 to 30 of about 82,857 (303)
Designing Biomaterial Platforms for Cardiac Tissue and Disease Modeling
Advanced NanoBiomed Research, 2021 Heart disease is one of the leading causes of death in the world. There is a growing demand for in vitro cardiac models that can recapitulate the complex physiology of the cardiac tissue.
Andrew House +3 more
doaj +1 more source
Overcoming the roadblocks to cardiac cell therapy using tissue engineering [PDF]
, 2017 Transplantations of various stem cells or their progeny have repeatedly improved cardiac performance in animal models of myocardial injury; however, the benefits observed in clinical trials have been generally less consistent.
Bolli, Roberto +12 more
core +2 more sources
Journal of the Serbian Chemical Society, 2005 We hypothesized that clinically sized (1-5 mm thick),compact cardiac constructs containing physiologically high density of viable cells (?108 cells/cm3) can be engineered in vitro by using biomimetic culture systems capable of providing oxygen transport and electrical stimulation, designed to mimic those in native heart.
Milica Radisic, Gordana Vunjak-Novakovic
openaire +4 more sources
Inflammation and Regeneration, 2018 Stem cell-based cardiac regenerative therapy is expected to be a promising strategy for the treatment of severe heart diseases. Pluripotent stem cells enabled us to reconstruct regenerated myocardium in injured hearts as an engineered tissue aiming for ...
Hidetoshi Masumoto, Jun K. Yamashita
doaj +1 more source
Heartbreak hotel: a convergence in cardiac regeneration [PDF]
, 2016 In February 2016, the Company of Biologists hosted an intimate gathering of leading international researchers at the forefront of experimental cardiovascular regeneration, with its emphasis on ‘Transdifferentiation and Tissue Plasticity in Cardiovascular
Schneider, MD
core +1 more source
Nanomaterials for Cardiac Tissue Engineering [PDF]
Molecules, 2020 End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that ...
Devang R. Amin +5 more
openaire +3 more sources
Co-axial wet-spinning in 3D Bioprinting: state of the art and future perspective of microfluidic integration [PDF]
, 2019 Nowadays, 3D bioprinting technologies are rapidly emerging in the field of tissue engineering and regenerative medicine as effective tools enabling the fabrication of advanced tissue constructs that can recapitulate in vitro organ/tissue functions ...
Barbetta, Andrea +3 more
core +1 more source
Chronic optical pacing conditioning of h-iPSC engineered cardiac tissues
Journal of Tissue Engineering, 2019 The immaturity of human induced pluripotent stem cell derived engineered cardiac tissues limits their ability to regenerate damaged myocardium and to serve as robust in vitro models for human disease and drug toxicity studies.
Marc Dwenger +10 more
doaj +1 more source
Polymer- and Hybrid-Based Biomaterials for Interstitial, Connective, Vascular, Nerve, Visceral and Musculoskeletal Tissue Engineering [PDF]
, 2020 In this review, materials based on polymers and hybrids possessing both organic and inorganic contents for repairing or facilitating cell growth in tissue engineering are discussed.
Abalymov, Anatolii +2 more
core +1 more source
Guided Tissue Regeneration in Heart Valve Replacement: From Preclinical Research to First-in-Human Trials [PDF]
, 2015 Heart valve tissue-guided regeneration aims to offer a functional and viable alternative to current prosthetic replacements. Not requiring previous cell seeding and conditioning in bioreactors, such exceptional tissue engineering approach is a very ...
Gerosa, Gino, Iop, Laura
core +4 more sources