Results 121 to 130 of about 10,037,177 (338)

Development of an interdisciplinary participatory design course with futures thinking for engineering students.

, 2016
In the future, engineers are expected to have innovative thinking and abilities of interdisciplinary and integration. Therefore, we combined three courses from Department of Civil Engineering, Graduate Institute of Building and Planning and Department of
Chen, M. D.;Lai, S. Y.;Song, M. M.;Hsieh, S. H.
core  

Exploring the roles of paradoxical tensions, paradoxical thinking, and team psychological capital on the creativity of engineering university students

BMC Psychology
Background The multifaceted challenges encountered by engineering university students generate paradoxical tensions, which serve as catalysts for fostering creativity.
Huifen Guo, Zhen Zhou, Fengqi Ma
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

A new direction in engineering mathematics: integrating mathematical thinking and engineering thinking

, 2013
This paper describes a proposal to enhance the teaching of Engineering Mathematics by integrating mathematical thinking and engineering thinking. In our previous research we had focused on the development and support of the mathematical thinking amongst ...
Ismail, Zaleha, Kashefi, Hamidreza, Firouzian, Soheila, Abdul Rahman, Roselainy, Mohammad Yusof, Yudariah   +4 more
core  

Systems Thinking Principles for Making Change

Systems
Traditionally, systems thinking support has relied on an ever-increasing plethora of systems tools, methods, and approaches. Arguably though, such support requires something different from, and more accessible than, detailed instruction on somewhat ...
Martin Reynolds
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Engineering Vanderbilt; Vol. 44 No. 01, 2003

, 2003
Engineering Vanderbilt (formerly Engineering News) is the newsletter of the Vanderbilt University School of EngineeringSchool of ...
Vanderbilt University. School of Engineering
core  

ROBOTICS IN PRIMARY SCHOOL: FROM PLAYFUL ACTIVITY TO CONSCIOUS STEM PROJECTING

Неперервна професійна освіта: теорія та практика
The article explores the role of educational robotics as a universal didactic tool within the context of Industry 4.0. The purpose of the study is to substantiate the mechanisms of a systematic transition from playful activity to conscious STEM ...
Marianna Shvardak , Oksana Popovych
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source