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Enhancing Gender [PDF]

open access: yesJournal of Bioethical Inquiry, 2022
AbstractTransgender healthcare faces a dilemma. On the one hand, access to certain medical interventions, including hormone treatments or surgeries, where desired, may be beneficial or even vital for some gender dysphoric trans people. But on the other hand, access to medical interventions typically requires a diagnosis, which, in turn, seems to imply ...
Hazem Zohny   +2 more
openaire   +3 more sources

Transcription Factor ELF1 Activates MEIS1 Transcription and Then Regulates the GFI1/FBW7 Axis to Promote the Development of Glioma

open access: yesMolecular Therapy: Nucleic Acids, 2021
Glioma is the most common malignancy in the central nervous system with no immediate prospect of a cure. Comprehensive understanding on the pathogenesis of the disorder contributes to a better outcome.
Meixiong Cheng   +5 more
doaj   +1 more source

Enhancing Photorealism Enhancement

open access: yesIEEE Transactions on Pattern Analysis and Machine Intelligence, 2023
Code and data available at https://github.com/intel-isl/PhotorealismEnhancement Video available at https://youtu.be ...
Stephan R. Richter   +2 more
openaire   +3 more sources

Enhancer Talk [PDF]

open access: yesEpigenomics, 2018
Enhancers are short noncoding segments of DNA (100-1000 bp) that control the temporal and spatial activity of genes in an orientation-independent manner. They can be separated from their target genes by large distances and are thus known as distal regulatory elements.
Snetkova, Valentina, Skok, Jane A
openaire   +4 more sources

Psychopharmaceutical Enhancers: Enhancing Identity? [PDF]

open access: yesNeuroethics, 2009
The use of psychopharmaceuticals to enhance human mental functioning such as cognition and mood has raised a debate on questions regarding identity and authenticity. While some hold that psychopharmaceutical substances can help users to ‘become who they really are’ and thus strengthen their identity and authenticity, others believe that the substances ...
Bolt, Ineke, Schermer, Maartje
openaire   +4 more sources

Diversity and Emerging Roles of Enhancer RNA in Regulation of Gene Expression and Cell Fate

open access: yesFrontiers in Cell and Developmental Biology, 2020
Enhancers are cis-regulatory elements in the genome that cooperate with promoters to control target gene transcription. Unlike promoters, enhancers are not necessarily adjacent to target genes and can exert their functions regardless of enhancer ...
Preston R. Arnold   +3 more
doaj   +1 more source

Interleukin-7 receptor signaling is crucial for enhancer-dependent TCRδ germline transcription mediated through STAT5 recruitment

open access: yesFrontiers in Immunology, 2022
γδ T cells play important roles in immune responses by rapidly producing large quantities of cytokines. Recently, γδ T cells have been found to be involved in tissue homeostatic regulation, playing roles in thermogenesis, bone regeneration and synaptic ...
Alonso Rodríguez-Caparrós   +6 more
doaj   +1 more source

Global Analysis of Transcription Start Sites in the New Ovine Reference Genome (Oar rambouillet v1.0)

open access: yesFrontiers in Genetics, 2020
The overall aim of the Ovine FAANG project is to provide a comprehensive annotation of the new highly contiguous sheep reference genome sequence (Oar rambouillet v1.0).
Mazdak Salavati   +14 more
doaj   +1 more source

Pterostilbene Changes Epigenetic Marks at Enhancer Regions of Oncogenes in Breast Cancer Cells

open access: yesAntioxidants, 2021
Epigenetic aberrations are linked to sporadic breast cancer. Interestingly, certain dietary polyphenols with anti-cancer effects, such as pterostilbene (PTS), have been shown to regulate gene expression by altering epigenetic patterns.
Sadaf Harandi-Zadeh   +11 more
doaj   +1 more source

iEnhancer-EBLSTM: Identifying Enhancers and Strengths by Ensembles of Bidirectional Long Short-Term Memory

open access: yesFrontiers in Genetics, 2021
Enhancers are regulatory DNA sequences that could be bound by specific proteins named transcription factors (TFs). The interactions between enhancers and TFs regulate specific genes by increasing the target gene expression.
Kun Niu   +5 more
doaj   +1 more source

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