Results 231 to 240 of about 2,230,930 (359)

Enhanced Cerebral Expression of MCT1 and MCT2 in a Rat Ischemia Model Occurs in Activated Microglial Cells [PDF]

, 2009
Tiago Moreira, Karin Pierre, Fumihiko Maekawa, Cendrine Repond, Aleta Cebere, Sture Liljequist, Luc Pellerin   +6 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Prediction of Enhancer RNAs in Chicken Genome. [PDF]

Int J Mol Sci
Grushina VA, Gagarina VS, Prasolov DE, Kolpakov FA, Gusev OA, Pintus SS.   +5 more
europepmc   +1 more source

Durability Enhancement of Concrete with Recycled Concrete Aggregate: The Role of Nano-ZnO [PDF]

Mazen J. Al‐Kheetan, Yazeed S. Jweihan, Musab Rabi, Seyed Hamidreza Ghaffar   +3 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

enhancer3D: 3D chromatin structures and enhancer-promoter distance profiles for archaic and modern human genomes. [PDF]

Nucleic Acids Res
Wlasnowolski M, Kozlov N, Wojcik M, Jacobs GS, Plewczynski D.   +4 more
europepmc   +1 more source

Tailored Regulation of Graphite Microcrystals via Tandem Catalytic Carbonization for Enhanced Electrochemical Performance of Hard Carbon in the Low‐Voltage Plateau [PDF]

Limin Zhou, Gaoyue Zhang, Chenchen Xu, Junxiao Li, Yanyan Liu, Baojun Li, Ao Wang, Kang Sun   +7 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Transcriptional pause release at enhancers mediates cell identity. [PDF]

NAR Cancer
Ekstrom TL, Johnsen SA.
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source