Use of time-of-flight mass spectrometry for large screening of organic pollutants in surface waters and soils from a rice production area in Colombia [PDF]
The irrigate district of Usosaldaña, an important agricultural area in Colombia mainly devoted to rice crop production, is subjected to an intensive use of pesticides.
Botero-Coy, Ana Maria+7 more
core +2 more sources
MDAN-21: A Bivalent Opioid Ligand Containing mu-Agonist and Delta-Antagonist Pharmacophores and Its Effects in Rhesus Monkeys [PDF]
MDAN-21, , a bivalent opioid ligand containing a mu-opioid receptor agonist (derived from oxymorphone) linked to the delta-opioid receptor antagonist (related to naltrindole) by a spacer of 21 atoms, was reported to have potent analgesic properties in ...
Aceto, Mario D.+6 more
core +4 more sources
Extraction optimization of antioxidant and hepatoprotective composition from Chicory. ABSTRACT Chicory (Cichorium intybus L.) roots are commonly roasted and ground to produce a coffee alternative, valued for its robust, nutty taste and absence of caffeine.
Aizhamal Baiseitova+9 more
wiley +1 more source
Importance of MS selectivity and chromatographic separation in LC-MS/MS-based methods when investigating pharmaceutical metabolites in water. Dipyrone as a case of study. [PDF]
Pharmaceuticals are emerging contaminants of increasing concern because of their presence in the aquatic environment and potential to reach drinking-water sources.
GRACIA LOR, EMMA+3 more
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Resveratrol and pterostilbene reduced the steatotic status of animals fed a high‐fat, high‐sucrose diet, involving differential and specific mechanisms of action for each stilbene. Thus, changes in riboflavin metabolism, nicotinamide mononucleotide metabolism, or in the LysoPC(18:1)‐mediated effects contribute to the specific actions of pterostilbene ...
Alfredo Fernández‐Quintela+5 more
wiley +1 more source
It aimed to observe the effects of TongDu TiaoShen (TDTS) electroacupuncture (EA) on the analgesia and central system of knee osteoarthritis (KOA) rats and explore its mechanism. SD rats were rolled into the blank group, model group (KOA), control group (
Xiahai Zheng+4 more
doaj +1 more source
Evaluation Of Acupuncture Therapy For Chronic Prostatitis/Chronic Pelvic Pain Syndrome [PDF]
Penyakit prostatitis kronikl sindrom sakit pelvis kronik merupakan sejenis sindrom yang mengecewakan, mengelirukan dan kerap ditemui.
Wen Huey, Shaun Lee
core +2 more sources
Updating the list of known opioids through identification and characterization of the new opioid derivative 3,4-dichloro-N- (2-(diethylamino)cyclohexyl)-N- methylbenzamide (U-49900) [PDF]
New psychoactive substances have been rapidly growing in popularity in the drug market as non-illegal drugs. In the last few years, an increment has been reported on the use of synthetic alternatives to heroin, the synthetic opioids.
Carbón, X.+7 more
core +1 more source
This study presents a novel method for rapidly evaluating dermal drug delivery systems (DDSs). Using mass spectrometry imaging and automated data analysis, it visualizes drug distribution within skin layers in under 10 min. Tested with three nanoscale DDSs for antifungal terbinafine, the approach reveals key differences in drug permeation depth and ...
Ravit Yakobi Arancibia+9 more
wiley +1 more source
Conformation-Specific Spectroscopy of Peptide Fragment Ions in a Low-Temperature Ion Trap [PDF]
We have applied conformer-selective infrared-ultraviolet (IR-UV) double-resonance photofragment spectroscopy at low temperatures in an ion trap mass spectrometer for the spectroscopic characterization of peptide fragment ions.
Boyarkin, Oleg+3 more
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