Results 61 to 70 of about 10,678 (183)

Use of time-of-flight mass spectrometry for large screening of organic pollutants in surface waters and soils from a rice production area in Colombia [PDF]

open access: yes, 2012
The irrigate district of Usosaldaña, an important agricultural area in Colombia mainly devoted to rice crop production, is subjected to an intensive use of pesticides.
Botero-Coy, Ana Maria   +7 more
core   +2 more sources

MDAN-21: A Bivalent Opioid Ligand Containing mu-Agonist and Delta-Antagonist Pharmacophores and Its Effects in Rhesus Monkeys [PDF]

open access: yes, 2012
MDAN-21, , a bivalent opioid ligand containing a mu-opioid receptor agonist (derived from oxymorphone) linked to the delta-opioid receptor antagonist (related to naltrindole) by a spacer of 21 atoms, was reported to have potent analgesic properties in ...
Aceto, Mario D.   +6 more
core   +4 more sources

Response Surface Methodology Optimization on Ultrasonic‐Assisted Extraction of Chicory (Cichorium intybus L.) and Their UPLC‐ESI‐QTOF‐MS Analysis, Antioxidant and Hepatoprotective Activity

open access: yeseFood, Volume 6, Issue 4, August 2025.
Extraction optimization of antioxidant and hepatoprotective composition from Chicory. ABSTRACT Chicory (Cichorium intybus L.) roots are commonly roasted and ground to produce a coffee alternative, valued for its robust, nutty taste and absence of caffeine.
Aizhamal Baiseitova   +9 more
wiley   +1 more source

Importance of MS selectivity and chromatographic separation in LC-MS/MS-based methods when investigating pharmaceutical metabolites in water. Dipyrone as a case of study. [PDF]

open access: yes, 2012
Pharmaceuticals are emerging contaminants of increasing concern because of their presence in the aquatic environment and potential to reach drinking-water sources.
GRACIA LOR, EMMA   +3 more
core   +2 more sources

Changes in Liver Metabolome Induced by Pterostilbene and Resveratrol in a Rat Model of Liver Steatosis

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Resveratrol and pterostilbene reduced the steatotic status of animals fed a high‐fat, high‐sucrose diet, involving differential and specific mechanisms of action for each stilbene. Thus, changes in riboflavin metabolism, nicotinamide mononucleotide metabolism, or in the LysoPC(18:1)‐mediated effects contribute to the specific actions of pterostilbene ...
Alfredo Fernández‐Quintela   +5 more
wiley   +1 more source

Research of the analgesic effects and central nervous system impact of electroacupuncture therapy in rats with knee osteoarthritis

open access: yesHeliyon
It aimed to observe the effects of TongDu TiaoShen (TDTS) electroacupuncture (EA) on the analgesia and central system of knee osteoarthritis (KOA) rats and explore its mechanism. SD rats were rolled into the blank group, model group (KOA), control group (
Xiahai Zheng   +4 more
doaj   +1 more source

Evaluation Of Acupuncture Therapy For Chronic Prostatitis/Chronic Pelvic Pain Syndrome [PDF]

open access: yes, 2007
Penyakit prostatitis kronikl sindrom sakit pelvis kronik merupakan sejenis sindrom yang mengecewakan, mengelirukan dan kerap ditemui.
Wen Huey, Shaun Lee
core   +2 more sources

Updating the list of known opioids through identification and characterization of the new opioid derivative 3,4-dichloro-N- (2-(diethylamino)cyclohexyl)-N- methylbenzamide (U-49900) [PDF]

open access: yes, 2017
New psychoactive substances have been rapidly growing in popularity in the drug market as non-illegal drugs. In the last few years, an increment has been reported on the use of synthetic alternatives to heroin, the synthetic opioids.
Carbón, X.   +7 more
core   +1 more source

A Rapid Assessment Approach for Skin Stratum‐Targeted Drug Delivery Systems Using Mass Spectrometry Imaging and Spatial Clustering

open access: yesSmall Science, Volume 5, Issue 8, August 2025.
This study presents a novel method for rapidly evaluating dermal drug delivery systems (DDSs). Using mass spectrometry imaging and automated data analysis, it visualizes drug distribution within skin layers in under 10 min. Tested with three nanoscale DDSs for antifungal terbinafine, the approach reveals key differences in drug permeation depth and ...
Ravit Yakobi Arancibia   +9 more
wiley   +1 more source

Conformation-Specific Spectroscopy of Peptide Fragment Ions in a Low-Temperature Ion Trap [PDF]

open access: yes, 2018
We have applied conformer-selective infrared-ultraviolet (IR-UV) double-resonance photofragment spectroscopy at low temperatures in an ion trap mass spectrometer for the spectroscopic characterization of peptide fragment ions.
Boyarkin, Oleg   +3 more
core  

Home - About - Disclaimer - Privacy