Methionine enkephalin(MENK) upregulated memory T cells in anti-influenza response [PDF]
BMC Immunology, 2023 Novel prophylactic drugs and vaccination strategies for protection against influenza virus should induce specific effector T-cell immune responses in pulmonary airways and peripheral lymphoid organs.
Jing Tian +6 more
doaj +2 more sources
Proteomics analysis of methionine enkephalin upregulated macrophages against infection by the influenza-A virus [PDF]
Proteome Science, 2023 Macrophages have a vital role in phagocytosis and antiviral effect against invading influenza viruses. Previously, we found that methionine enkephalin (MENK) inhibited influenza virus infection by upregulating the “antiviral state” of macrophages.
Wenrui Fu +5 more
doaj +2 more sources
Stabilization and Reactions of Sulfur Radical Cations: Relevance to One-Electron Oxidation of Methionine in Peptides and Proteins [PDF]
CHIMIA, 2008 Methionine is a key amino acid that has numerous roles in essential vital processes. Moreover, methionine oxidation is biologically important during conditions of oxidative stress and represents an important step in the development of some ...
Krzysztof Bobrowski +2 more
doaj +3 more sources
Cancer Management and Research, 2018 Xiaonan Wang,1 Jing Tian,1 Xue Jiao,2 Jin Geng,3 Reizhe Wang,4 Ning Liu,5 Xinghua Gao,6 Noreen Griffin,7 Yuan Gao,8 Fengping Shan1 1Department of Immunology, College of Basic Medical Science, China Medical University, Shenyang, China; 2Department of ...
Wang X +9 more
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Methionine enkephalin (MENK) protected macrophages from ferroptosis by downregulating HMOX1 and ferritin [PDF]
Proteome ScienceObjective The aim of this work was to investigate the immunological effect of MENK by analyzing the protein spectrum and bioinformatics of macrophage RAW264.7, and to explore the relationship between macrophage and ferroptosis.
Jing Tian +5 more
doaj +2 more sources
Biased Metropolis Sampling for Rugged Free Energy Landscapes [PDF]
AIP Conference Proceedings Vol.690, 63-73 (2003), 2003 Metropolis simulations of all-atom models of peptides (i.e. small proteins) are considered. Inspired by the funnel picture of Bryngelson and Wolyness, a transformation of the updating probabilities of the dihedral angles is defined, which uses probability densities from a higher temperature to improve the algorithmic performance at a lower temperature.
Berg, Bernd A.
arxiv +5 more sources
Electroless Ionization Mass Spectrometry Using a Compact Electrokinetic Ionization Source. [PDF]
Anal ChemWe introduce a new ionization technique for compact, portable mass spectrometers. It consists of a syringe with sample liquid capped by a self-ionizing spray nozzle containing a microfabricated nozzle chip.
Kooij S +4 more
europepmc +3 more sources
Exposure to exogenous enkephalins disrupts reproductive development in the Eastern lubber grasshopper, Romalea microptera (Insecta: Orthoptera). [PDF]
PLoS ONE, 2012 Enkephalins play a major role in reproductive physiology in crustaceans; however their role in reproductive development in insects is largely unknown. We investigated the effect of exposure to exogenous leucine-enkephalin (Leu-Enk), methionine-enkephalin
Sandeep Kumar +4 more
doaj +1 more source
Iraqi Journal of Pharmaceutical Sciences, 2017 A small number of researches were done in the design and synthesis of enkephalin analogues that are able to resist degradation effect of proteolytic enzymes with good bioavailability and half-lives.Through studying structure activity relationships we ...
Muthanna S. Al-Ttaee +2 more
doaj +3 more sources
THE DISTRIBUTION OF METHIONINE‐ENKEPHALIN AND LEUCINE‐ENKEPHALIN IN THE BRAIN AND PERIPHERAL TISSUES [PDF]
British Journal of Pharmacology, 1977 A method is described for the rapid extraction of opioid peptides from the brain and other tissues. The method is based on acid extraction of tissues followed by adsorption of the extract onto Amberlite XAD‐2 resin. Elution with methanol separates the enkephalins and α‐endorphin from β‐endorphin.
Jeffery Hughes +2 more
openaire +5 more sources