Results 31 to 40 of about 9,145 (201)

Biochemical and clinical impact of organic uremic retention solutes : a comprehensive update [PDF]

open access: yes, 2018
In this narrative review, the biological/biochemical impact (toxicity) of a large array of known individual uremic retention solutes and groups of solutes is summarized.
Abel   +45 more
core   +3 more sources

Biomimetic Chemistry on Tandem Protein/Lipid Damages under Reductive Radical Stress

open access: yesCHIMIA, 2008
The study of radical stress in the biological environment needs a comprehensive vision of all possible reactive species and their mechanisms. Among them, reductive stress is evaluated for its selective target of sulfur-containing compounds.
Sílvia Atrian   +8 more
doaj   +1 more source

Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. [PDF]

open access: yes, 2010
Despite abundant expression of DNA methyltransferases (Dnmts) in brain, the regulation and behavioral role of DNA methylation remain poorly understood. We found that Dnmt3a expression was regulated in mouse nucleus accumbens (NAc) by chronic cocaine use ...
Bolaños, Carlos A   +26 more
core   +3 more sources

Multi-physics Extension of OpenFMO Framework

open access: yes, 2007
OpenFMO framework, an open-source software (OSS) platform for Fragment Molecular Orbital (FMO) method, is extended to multi-physics simulations (MPS). After reviewing the several FMO implementations on distributed computer environments, the subsequent ...
George Maroulis   +11 more
core   +1 more source

Electron scattering from molecules and molecular aggregates of biological relevance [PDF]

open access: yes, 2017
In this Topical Review we survey the current state of the art in the study of low energy electron collisions with biologically relevant molecules and molecular clusters.
Allan M   +33 more
core   +1 more source

Complex Regional Pain Syndrome and Methionine-Enkephalin [PDF]

open access: yesClinical Chemistry, 2006
Complex regional pain syndrome (CRPS), or reflex sympathetic dystrophy, develops after trauma or surgery and is characterized by pain that is disproportionate to the initial injury and is not confined to the nerve or nerve root distribution (1)(2)(3)(4)(5). Symptoms involve the autonomic, somatosensory, and sympathetic nervous systems.
Olivier W V, van den Brink   +5 more
openaire   +2 more sources

Dynamic Metabolic Footprinting Reveals the Key Components of Metabolic Network in Yeast Saccharomyces cerevisiae [PDF]

open access: yes, 2014
Metabolic footprinting offers a relatively easy approach to exploit the potentials of metabolomics for phenotypic characterization of microbial cells.
Chumnanpuen, Pramote   +3 more
core   +3 more sources

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

open access: yesMed Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang   +12 more
wiley   +1 more source

Backbone Protecting Groups for Enhanced Peptide and Protein Synthesis

open access: yesAngewandte Chemie, Volume 137, Issue 33, August 11, 2025.
This review provides a comprehensive account of the use of backbone N‐protecting groups in peptide synthesis. It includes detailed synthetic methods relating to their introduction and removal and their application to “difficult” peptides and proteins of biological significance in both academic and industry contexts.
Samuel J. Paravizzini   +3 more
wiley   +2 more sources

Nicotine Effects and the Endogenous Opioid System

open access: yesJournal of Pharmacological Sciences, 2014
.: Nicotine (NIC) is an exogenous ligand of the nicotinic acetylcholine receptor (nAChR), and it influences various functions in the central nervous system. Systemic administration of NIC elicits the release of endogenous opioids (endorphins, enkephalins,
Shiroh Kishioka   +3 more
doaj   +1 more source

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