Results 11 to 20 of about 9,189 (204)
The role of immune responses and microbiota in adipose tissue homeostasis. [PDF]
Abstract figure legend Gut microbiota regulate white and brown adipose tissue homeostasis via modulation of gut hormone secretion, activation of pathogen‐associated pattern receptors and production of bioactive molecules and metabolites such as short‐chain fatty acids, endocannabinoids, amino acid derivates and bile acids, all of which affect ...
Azar S, Rehermann B.
europepmc +2 more sources
Computational Approach for Protein Structure Prediction [PDF]
ObjectivesTo predict the structure of protein, which dictates the function it performs, a newly designed algorithm is developed which blends the concept of self-organization and the genetic algorithm.MethodsAmong many other approaches, genetic algorithm ...
Amouda Venkatesan +4 more
doaj +1 more source
Endogenous opioids participate in growth regulation. Liver regeneration relates to growth. Thus, we explored the expression of methionine enkephalin and of the delta opioid receptor 1 immunoreactivities with a polyclonal rabbit antibody in deparaffinized
Vijaya D. Boyella +2 more
doaj +1 more source
Proenkephalin (PENK), as the precursor of endogenous opioid enkephalin (ENK), is widely present in the nervous system and plays an important role in animal food addiction and rewarding behavior.
Yingcen Li +3 more
doaj +1 more source
Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease. [PDF]
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Farag M +15 more
europepmc +2 more sources
Three protected tetrapeptides [PDF]
The structures of three protected tetrapeptides, containing the Boc-Gly-Gly-Phe-X-OMe chain, tert-butoxycarbonyl-glycy-glycl-phenylalanine-leucine methyl ester dihydrate, Boc-Gly-Gly-L-Phe-D-Leu-OMe, C25H38N4O7·2H2O, tert-butoxycarbonyl-glycy-glycl ...
Casalone, Gianluigi, Fenude, Emma
core +1 more source
Opioid Receptors in Immune and Glial Cells-Implications for Pain Control [PDF]
Opioid receptors comprise μ (MOP), δ (DOP), κ (KOP), and nociceptin/orphanin FQ (NOP) receptors. Opioids are agonists of MOP, DOP, and KOP receptors, whereas nociceptin/orphanin FQ (N/OFQ) is an agonist of NOP receptors.
Celik, Melih Ö., Machelska, Halina
core +1 more source
Methionine-Enkephalin in Bone and Joint Tissues [PDF]
Abstract Methionine-enkephalin (met-enk), an endogenous opiate, mimics many of the effects of morphine by binding to opiate receptors, thereby eliciting similar cellular and behavioral effects. Using biochemical and immunohistochemical techniques, several peptides have been identified in bone and joint tissues.
A M, Elhassan +4 more
openaire +2 more sources
Methionine enkephalin: immunomodulator in normal volunteers, cancer and AIDS patients
Clinical studies of the immunological effects of methionine enkephalin in normal volunteers, cancer, and AIDS patients are summarized. The major immunology changes seen were increases in T cell subsets, natural killer activity, as well as mitogen ...
Nicholas P. Plotnikoff +3 more
doaj +1 more source
INTRODUCTION: In the alpaca diencephalon, the distribution of immunoreactive cell bodies and fibers containing methionine-enkephalin (MET) or substance P (SP) has been studied. MATERIAL AND METHODS: The immunohistochemical study was performed by standard
Pablo Sánchez +4 more
doaj +1 more source

