Results 21 to 30 of about 9,189 (204)

Methionine-enkephalin-treatment suppresses the pituitary-ovary axis in the cichlid fish Oreochromis mossambicus

Aquaculture Reports, 2020
The involvement of endogenous opioid peptides in regulation of reproductive activity is implicated in a majority of vertebrates. Methionine-enkephalin (M-ENK) is an endogenous opioid peptide neurotransmitter produced in the central nervous system ...
C.B. Ganesh, Vijayalaxmi
doaj   +1 more source

Stabilization and Reactions of Sulfur Radical Cations: Relevance to One-Electron Oxidation of Methionine in Peptides and Proteins

CHIMIA, 2008
Methionine is a key amino acid that has numerous roles in essential vital processes. Moreover, methionine oxidation is biologically important during conditions of oxidative stress and represents an important step in the development of some ...
Krzysztof Bobrowski, Chantal Houée-Levin, Bronislaw Marciniak   +2 more
doaj   +1 more source

New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]

, 1984
The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Berlit, Peter, Kessler, C., Krause, Klaus-Henning, Reuther, R.   +3 more
core   +1 more source

Actions of D-Ala2-D-Leu5-enkephalin and dynorphin A (1–17) on neocortical neurons in vitro [PDF]

, 1984
Intracellular recordings were made from neocortical neurons in vitro. Application of D-Ala2-D-Leu5-enkephalin (DADL) by different methods produced a decrease in EPSP amplitude and in the amplitude of L-glutamate-induced depolarizations without changes in
B Sutor, Khachaturian, Lewis, Quirion, Satoh, W Zieglgänsberger, Weber, Williams, Williams, Yoshimura, Zieglgänsberger, Zieglgänsberger   +11 more
core   +1 more source

Maturation of Circulatory Responses to Methionine-Enkephalin [PDF]

Pediatric Research, 1983
The cardiovascular and respiratory effects of the naturally occurring endogenous opiate, methionine-enkephalin, were studied in 23 fetal sheep, five newborn lambs, 15 pregnant sheep, and four nonpregnant ewes. The opiate peptide produced dose-dependent decreases in heart rate and blood pressure in fetal and neonatal lambs but increased heart rate and ...
E F, Lagamma, J, Itskovitz, A M, Rudolph
openaire   +2 more sources

Biased Metropolis Sampling for Rugged Free Energy Landscapes [PDF]

, 2003
Metropolis simulations of all-atom models of peptides (i.e. small proteins) are considered. Inspired by the funnel picture of Bryngelson and Wolyness, a transformation of the updating probabilities of the dihedral angles is defined, which uses ...
Berg, Bernd A.
core   +3 more sources

Methionine Enkephalin Suppresses Osteocyte Apoptosis Induced by Compressive Force through Regulation of Nuclear Translocation of NFATc1

JBMR Plus, 2020
Mechanical stress stimulates bone remodeling, which occurs through bone formation and resorption, resulting in bone adaptation in response to the mechanical stress. Osteocytes perceive mechanical stress loaded to bones and promote bone remodeling through
Chisumi Sogi, Nobuo Takeshita, Wei Jiang, Siyoung Kim, Toshihiro Maeda, Michiko Yoshida, Toshihito Oyanagi, Arata Ito, Seiji Kimura, Daisuke Seki, Ikuko Takano, Yuichi Sakai, Ikuma Fujiwara, Shigeo Kure, Teruko Takano‐Yamamoto   +14 more
doaj   +1 more source

Cerebrospinal fluid levels of opioid peptides in fibromyalgia and chronic low back pain [PDF]

, 2004
Background The mechanism(s) of nociceptive dysfunction and potential roles of opioid neurotransmitters are unresolved in the chronic pain syndromes of fibromyalgia and chronic low back pain.
James N Baraniuk, Gail Whalen, Jill Cunningham, Daniel J Clauw, F Wolfe, F Wolfe, RC Coghill, RH Gracely, LA Bradley, K Fukuda, E Lapossy, T Yoshimasa, A Rosen, M Spetea, JN Baraniuk, JE Ware, S Lyrenaes, H Vaeroy, L Terenius, T Giesecke, MB Yunus, HA Smythe, Z Liu, DX Lui, H Brooks   +24 more
core   +2 more sources

Targeted Cell Reprogramming Produces Analgesic Chromaffin-Like Cells from Human Mesenchymal Stem Cells

Cell Transplantation, 2013
Transplantation of allogeneic adrenal chromaffin cells demonstrated the promise of favorable outcomes for pain relief in patients. However, there is a very limited availability of suitable human adrenal gland tissues, genetically well-matched donors in ...
T. Qu M.D., Ph.D., G. Shi, K. Ma, H. N. Yang, W. M. Duan, G. D. Pappas   +5 more
doaj   +1 more source

Genetically Engineered Human Mesenchymal Stem Cells Produce Met-Enkephalin at Augmented Higher Levels in Vitro

Cell Transplantation, 2006
We have reported that transplantation of adrenal medullary chromaffin cells that release endogenous opioid peptides into pain modulatory regions in the CNS produce significant antinociceptive effects in patients with terminal cancer pain.
Ikuko Sugaya, Tingyu Qu, Kiminobu Sugaya, George D. Pappas   +3 more
doaj   +1 more source