Results 51 to 60 of about 9,145 (201)

Oral naltrexone treatment for cholestatic pruritus: A double-blind, placebo-controlled study [PDF]

, 1997
Background and Aims: The efficacy of currently available therapeutic agents for cholestatic pruritus is often disappointing. The aim of this study was to assess the antipruritic effect of naltrexone, an oral opiate receptor antagonist.
Bertolotti, M. (M.), Buuren, H.R. (Henk) van, Hop, W.C.J. (Wim), Sternieri, E. (E.), Vitale, G. (G.), Wolfhagen, F.H.J. (Franciscus)   +5 more
core   +4 more sources

‘Acetaldehyde‐enkephalins’: elucidation of the structure of the acetaldehyde adducts of methionine‐enkephalin and leucine‐enkephalin [PDF]

FEBS Letters, 1980
The two major endogenous opioid pentapeptides, methionine-enkephalin and leucine-enkephalin [ 1,2] rapidly react with acetaldehyde, under very mild conditions, to give an ‘acetaldehyde-enkephalin’ adduct, referred to as ‘acetaldehyde-enkephalin [Met’] and ‘acetaldehyde-enkephalin [Leu”], respectively 231.
Summers, Michael C., Gidley, Michael J., Sanders, Jeremy K.   +2 more
openaire   +3 more sources

Metabolic signatures of the integrated profile of cardiovascular autonomic modulation and cardiorespiratory fitness in apparently healthy individuals

Physiological Reports, Volume 14, Issue 2, January 2026.
Abstract Cardiovascular autonomic modulation (CAM) and cardiorespiratory fitness (CRF) are well‐established predictors of health. Identifying metabolites associated with integrated CAM‐CRF profiles may help characterize healthy physiological states.
Étore De Favari Signini, Alex Castro, Patrícia Rehder‐Santos, Juliana Cristina Milan‐Mattos, Juliana Magalhães de Oliveira, Alberto Porta, Renato Lajarim Carneiro, Antônio Gilberto Ferreira, Regina Vincenzi Oliveira, Aparecida Maria Catai   +9 more
wiley   +1 more source

Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]

, 2004
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core  

Pro-opiomelanocortin co-localizes with corticotropin-releasing factor in axon terminals of the noradrenergic nucleus locus coeruleus [PDF]

, 2006
We previously demonstrated that the opioid peptide, enkephalin, and corticotropin-releasing factor (CRF) are occasionally co-localized in individual axon terminals but more frequently converge on common dendrites in the locus coeruleus (LC).
Glaser, Julia D., Magtoto, Ronaldo, Reyes, Beverly A.S., van Bockstaele, Elisabeth K.   +3 more
core   +2 more sources

Characterization and Identification of Potential Antioxidant, Antidiabetic, and Antihypertensive Peptides From Hydrolysates of Tenebrio molitor Flour and Its Protein Concentrate

Journal of Food Science, Volume 90, Issue 10, October 2025.
ABSTRACT Insects are recognized as a potential alternative source of proteins and have been studied in recent years as a substrate for enzymatic hydrolysis to obtain bioactive peptides. This study aimed to evaluate the production of hydrolysates with antioxidant, antidiabetic, and antihypertensive properties from mealworm (Tenebrio molitor) flour and ...
Francielle Miranda de Matos, Ruann Janser Soares de Castro   +1 more
wiley   +1 more source

Serotoninergic, peptidergic and GABAergic innervation of the ventrolateral and dorsolateral motor nuclei in the cat S1/S2 segments: An immunofluorescence study [PDF]

, 1994
Indirect single- and double-staining immunofluorescence techniques were used to study the serotoninergic, peptidergic and GABAergic innervation of the ventrolateral (Onuf's nucleus) and dorsolateral (innervating intrinsic foot sole muscles) nuclei ...
Arvidsson, U. (U.), Hökfelt, T. (T.), Ramírez-León, V. (V.), Ulfhake, B. (B.), Verhofstad, A.A. (Albert), Visser, T.J. (Theo)   +5 more
core   +1 more source

Lentil Flours as Sustainable Source of Proteins for the Food Industry

Sustainable Food Proteins, Volume 3, Issue 3, September 2025.
Lentils, due to their accessibility, sustainability, and high nutritional value, emerge as a promising option as protein flour for food development. This study evaluated different functional and nutritional properties of lentil flours. ABSTRACT The growing transition toward a plant‐based diet, coupled with the need for sustainable dietary protein ...
S. M. Pontoni, A.G. Garzón, G. D. Heinen, S.R. Drago   +3 more
wiley   +1 more source

Chronic Intermittent Ethanol and Withdrawal Suppress Evoked and Spontaneous GABA Release Onto Distinct Populations of Basolateral Amygdala Principal Neurons

Addiction Biology, Volume 30, Issue 9, September 2025.
Rat basolateral amygdala principal neurons projecting to the nucleus accumbens (BLANAc) and bed nucleus of the stria terminalis (BLABNST) represent independent cell populations. In male BLANAc neurons only (left), CIE/WD decreases feedforward GABA release from lateral paracapsular interneurons.
Michaela E. Price, Hailey X. Egido‐Betancourt, Sarah E. Sizer, Brian P. Parrish, Nancy J. Alexander, Kimberly F. Raab‐Graham, Brian A. McCool   +6 more
wiley   +1 more source

How Far Does a Receptor Influence Vibrational Properties of an Odorant? [PDF]

, 2016
The biophysical mechanism of the sense of smell, or olfaction, is still highly debated. The mainstream explanation argues for a shape-based recognition of odorant molecules by olfactory receptors, while recent investigations suggest the primary olfactory
Kongsted, Jacob, List, Nanna Holmgaard, Reese, Anna, Solov'yov, Ilia A   +3 more
core   +3 more sources