Results 151 to 160 of about 110,810 (218)

Methionine-enkephalin, leucine-enkephalin, methionine-enkephalin-Arg6-Phe7 and methionine-enkephalin-Arg6-Gly7-Leu8 in human pheochromocytoma

Life Sciences, 1983
Methionine-enkephalin(met-enkephalin)-, leucine-enkephalin(leu-enkephalin)-, methionine-enkephalin-Arg6-Phe7(met-enkephalin-Arg-Phe)- and methionine-enkephalin-Arg6-Gly7-Leu8(met-enkephalin-Arg-Gly-Leu)-like immunoreactivities(-LI) were studied in 16 pheochromocytomas by radioimmunoassays (RIAs) for these four opioid peptides. Met-enkephalin-Arg-Phe-LI
Yoshio Ikeda, Takaaki Yoshimasa, Mitsuaki Suda, Kazuwa Nakao, Makoto Sakamoto, Hiroo Imura   +5 more
openaire   +4 more sources

Demonstration and characterization of immunoreactive methionine-enkephalin, leucine-enkephalin, methionine-enkephalin-Arg6-Gly7-Leu8 and methionine-enkephalin-Arg6-Phe7 in human phaeochromocytoma

Acta Endocrinologica, 1984
Abstract. To elucidate whether or not human phaeochromocytoma contains methionine-enkephalin-Arg6-Gly7-Leu8 (Met-enkephalin-Arg-Gly-Leu) and methionine-enkephalin-Arg6-Phe7 (Met-enkephalin-Arg-Phe) together with methionine-enkephalin (Met-enkephalin) and leucine-enkephalin (Leu-enkephalin), all of which are known to exist in the same precursor molecule
Shinichiro Shimbo, Takashi Ishihara, Satoshi Hamada, Yoshio Ikeda, Hiroo Imura, Shigeru Matsukura, Kazuwa Nakao, Mitsuaki Suda, Masataka Manno, Narito Morii, Teruya Yoshimi, Takaaki Youshimasa, Makoto Sakamoto, Toru Mori   +13 more
openaire   +4 more sources

Distribution of methionine-enkephalin in the minipig brainstem

Journal of Chemical Neuroanatomy, 2013
We have studied the distribution of immunoreactive cell bodies and axons are containing methionine-enkephalin in the minipig brainstem. Immunoreactive axons were widely distributed, whereas the distribution of perikarya was less widespread. A high or moderate density of axons containing methionine-enkephalin were found from rostral to caudal levels in ...
Rafael Coveñas, Elena Vecino, Manuel Lisardo Sánchez   +2 more
openaire   +4 more sources

The paradoxical role of methionine enkephalin in tumor responses

European Journal of Pharmacology, 2020
Methionine enkephalin (MENK) is an opioid peptide composed of five amino acids with multiple biological activities. Since its discovery, MENK has become prominent in neuroregulation and immunoregulation. Tumors have increasingly been a spotlight because of their terrible trends and refractory characteristic.
Cheng Tian, Ming Xiang, Yali Tuo, Lili Lu   +3 more
openaire   +4 more sources

Methionine‐enkephalin peptides in human teeth

International Journal of Peptide and Protein Research, 1988
The presence of the free opioid pentapeptide methionine enkephalin (ME) and of ME‐containing peptide(s) was established firmly in decalcified, depulped human teeth by using a combination of methods including RP‐HPLC, radioimmunoassay, radioreceptorassay, trypsin, carboxypeptidase B, fast atom bombardment mass spectrometry, and MS/MS methodology ...
Dominic M. Desiderio, Peter W. Tinsley, Francis S. Tanzer, Genevieve H. Fridland, John T. Killmar, Chhabil Dass, Emirgul Tolun   +6 more
openaire   +4 more sources

Methionine enkephalin regulates microglia polarization and function

International Immunopharmacology, 2016
Methionine enkephalin (MENK), an opioid peptide, is known to function as a regulator in the immune system. As microglia are considered the most important immune cells in the central nervous system (CNS), we aimed to assess the function of MENK on microglia polarization and tumoricidal responses.
Lulu Wen, Xuxu Xu, Juan Feng, Zhiyong Zhai, Fengping Shan, Shuo Zhang, Yan Gao   +6 more
openaire   +3 more sources

METHIONINE ENKEPHALIN AND ISOSTERIC ANALOGUES

International Journal of Peptide and Protein Research, 1980
Biological activities are reported for two different types of analogues of methionine enkephalin. Cyclic analogues, bridged between the amino‐ and carboxy‐ terminals of the parent peptide, are inactive. In contrast, significant levels of activity are displayed by linear isosterically modified analogues in which the Tyr1 ‐Gly2 peptide bond is replaced ...
Robert Sharpe, Derek Hudson, Michael Szelke   +2 more
openaire   +3 more sources

Parallel distribution of methionine-enkephalin-arg6-gly7-leu8 with methionine-enkephalin, leucine-enkephalin and methionine-enkephalin-arg6-phe7 in human and bovine brains

Life Sciences, 1983
Using specific radioimmunoassays(RIAs) for methionine-enkephalin(Met-Enk), leucine-enkephalin(Leu-Enk), methionine-enkephalin-Arg6-Gly7-Leu8 (Met-Enk-Arg-Gly-Leu) and methionine-enkephalin-Arg6-Phe7 (Met-Enk-Arg-Phe), we studied the regional distribution of these opioid peptides in human and bovine brains.
Takaaki Yoshimasa, Noboru Yanaihara, Yoshio Ikeda, Makoto Sakamoto, Hiroo Imura, Mitsuaki Suda, Kazuwa Nakao   +6 more
openaire   +3 more sources