Results 161 to 170 of about 9,145 (201)

Methionine enkephalin regulates microglia polarization and function

International Immunopharmacology, 2016
Methionine enkephalin (MENK), an opioid peptide, is known to function as a regulator in the immune system. As microglia are considered the most important immune cells in the central nervous system (CNS), we aimed to assess the function of MENK on microglia polarization and tumoricidal responses.
Xuxu, Xu, Yan, Gao, Lulu, Wen, Zhiyong, Zhai, Shuo, Zhang, Fengping, Shan, Juan, Feng   +6 more
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Influence of Ethanol Dependence and Methionine Enkephalin Antisense on Serum Endomorphin‐1 and Methionine Enkephalin Levels

Alcoholism: Clinical and Experimental Research, 2004
Abstract: Background: Opiate peptides are involved in the physical dependence on ethanol. Levels of methionine enkephalin (MEnk), for example, are affected by ethanol. No study on the effect of ethanol on endomorphin, the endogenous ligand for the μ‐opiate receptor, has yet been conducted.Methods: We examined the effect of ethanol ingestion on serum
William A, Banks, Vijaya B, Kumar, John E, Morley   +2 more
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Phencyclidine decreases methionine-enkephalin content in rat striatum

Neuroscience Letters, 1983
The acute administration of phencyclidine induced a decrease in methionine-enkephalin levels in rat striatum, as measured by specific radioimmunoassay. The maximum decrease (about 40% with respect to controls) was obtained at a dose of 20 mg/kg, 30 min after intraperitoneal injection.
FRATTA, WALTER, ZIVKOVIC B, GESSA G.
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Methionine enkephalin and isosteric analogues. Part II.: Receptor conformation of methionine enkephalin.

International journal of peptide and protein research, 1980
Biological activities are reported for two different types of analogues of methionine enkephalin. Cyclic analogues, bridged between the amino- and carboxy- terminals of the parent peptide, are inactive. In contrast, significant levels of activity are displayed by linear isosterically modified analogues in which the Tyr1-Gly2 peptide bond is replaced by
D, Hudson, R, Sharpe, M, Szelke
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Eine vereinfachte Synthese von Methionin‐Enkephalin

Journal für Praktische Chemie, 1978
A Convenient Synthesis of Methionin‐EnkephalinAn efficient synthesis of methionin‐enkephalin has been developed by prolongation of the C‐terminal amino acid methylester using Boc‐Phe‐OHNomenklatur und Abkürzungen nach den Regeln der IUPAC‐IUB‐Commission on Bichemical Nomenclature: Hoppe‐Seyler's Z. physiol. Chem. 348, 256 (1967), J. Biol. Chem.
Günter Losse, Klaus‐Dieter Wehrstedt
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Effect of methionine-enkephalin on xanthophore aggregation

Peptides, 1980
The intracranial injection of an opioid antagonist (naloxone) caused aggregation of xanthophores in goldfish scales. This aggregating effect produced by naloxone was inhibited by an injection of methionine-enkephalin (M-ENK). M-ENK, when injected together with melatonin which normally produces aggregation of xanthophores, interfered with the effect of ...
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Methionine enkephalin metabolism by murine macrophage ectopeptidase(s)

Regulatory Peptides, 1994
Ectopeptidases which hydrolyze opioid and other neuropeptides have been identified in brain, kidney and intestine. In this study, identification of the enzymes metabolizing the opioid peptide methionine enkephalin (YGGFM) in murine macrophages was undertaken.
B C, Miller, A, Ackroyd, L B, Hersh, G L, Cottam   +3 more
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Biosynthetic origin and receptor conformation of methionine enkephalin

Nature, 1976
RECENT reports have shown that the brain contains an endogenous peptide with opiate-like activity1–3 and similar peptides have been found in the pituitary4,5,13. One of the brain peptides, known as methionine enkephalin, was identified as a pentapeptide Tyr–Gly–Gly–Phe–Met6, and evidence was presented that a minor component may have leucine in place of
A F, Bradbury, D G, Smyth, C R, Snell
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Plasma methionine-enkephalin in PTSD

Biological Psychiatry, 1991
M E, Wolf, A D, Mosnaim, J, Puente, R, Ignacio   +3 more
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Total Synthesis of Methionine‐Enkephalin

Angewandte Chemie International Edition in English, 1976
W, Voelter, C, Bürvenich, H, Horn, H, Kalbacher, E, Pietrzik   +4 more
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