Results 11 to 20 of about 110,810 (218)

p-Cresol and p-Cresyl Sulphate Boost Oxidative Stress: A Systematic Review of Recent Evidence. [PDF]

Basic Clin Pharmacol Toxicol
ABSTRACT Recent studies have emphasized the significant role of p‐cresol and its conjugated form, p‐cresyl sulphate (PCS), in enhancing oxidative stress, leading to potential detrimental effects on various biological systems. Both p‐cresol and PCS contribute to increased production of reactive oxygen species (ROS), which can result in tissue damage ...
Renaldi R, Wiguna T, Persico AM, Tanra AJ.   +3 more
europepmc   +2 more sources

Actions of D-Ala2-D-Leu5-enkephalin and dynorphin A (1–17) on neocortical neurons in vitro [PDF]

, 1984
Intracellular recordings were made from neocortical neurons in vitro. Application of D-Ala2-D-Leu5-enkephalin (DADL) by different methods produced a decrease in EPSP amplitude and in the amplitude of L-glutamate-induced depolarizations without changes in
B Sutor, Khachaturian, Lewis, Quirion, Satoh, W Zieglgänsberger, Weber, Williams, Williams, Yoshimura, Zieglgänsberger, Zieglgänsberger   +11 more
core   +1 more source

Methionine enkephalin: immunomodulator in normal volunteers, cancer and AIDS patients

Memorias do Instituto Oswaldo Cruz, 1987
Clinical studies of the immunological effects of methionine enkephalin in normal volunteers, cancer, and AIDS patients are summarized. The major immunology changes seen were increases in T cell subsets, natural killer activity, as well as mitogen ...
Nicholas P. Plotnikoff, Gerald C. Miller, Nadim F. Nimeh, Joseph Wybran   +3 more
doaj   +1 more source

Three protected tetrapeptides [PDF]

, 1996
The structures of three protected tetrapeptides, containing the Boc-Gly-Gly-Phe-X-OMe chain, tert-butoxycarbonyl-glycy-glycl-phenylalanine-leucine methyl ester dihydrate, Boc-Gly-Gly-L-Phe-D-Leu-OMe, C25H38N4O7·2H2O, tert-butoxycarbonyl-glycy-glycl ...
Casalone, Gianluigi, Fenude, Emma
core   +1 more source

Stabilization and Reactions of Sulfur Radical Cations: Relevance to One-Electron Oxidation of Methionine in Peptides and Proteins

CHIMIA, 2008
Methionine is a key amino acid that has numerous roles in essential vital processes. Moreover, methionine oxidation is biologically important during conditions of oxidative stress and represents an important step in the development of some ...
Krzysztof Bobrowski, Chantal Houée-Levin, Bronislaw Marciniak   +2 more
doaj   +1 more source

Methionine-Enkephalin in Bone and Joint Tissues [PDF]

Journal of Bone and Mineral Research, 1998
Abstract Methionine-enkephalin (met-enk), an endogenous opiate, mimics many of the effects of morphine by binding to opiate receptors, thereby eliciting similar cellular and behavioral effects. Using biochemical and immunohistochemical techniques, several peptides have been identified in bone and joint tissues.
Kjell Hultenby, J. Bergstrom, J. U. Lindgren, Abdu Adem, Adlan M. Elhassan   +4 more
openaire   +3 more sources

New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]

, 1984
The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Berlit, Peter, Kessler, C., Krause, Klaus-Henning, Reuther, R.   +3 more
core   +1 more source

Methionine Enkephalin Suppresses Osteocyte Apoptosis Induced by Compressive Force through Regulation of Nuclear Translocation of NFATc1

JBMR Plus, 2020
Mechanical stress stimulates bone remodeling, which occurs through bone formation and resorption, resulting in bone adaptation in response to the mechanical stress. Osteocytes perceive mechanical stress loaded to bones and promote bone remodeling through
Chisumi Sogi, Nobuo Takeshita, Wei Jiang, Siyoung Kim, Toshihiro Maeda, Michiko Yoshida, Toshihito Oyanagi, Arata Ito, Seiji Kimura, Daisuke Seki, Ikuko Takano, Yuichi Sakai, Ikuma Fujiwara, Shigeo Kure, Teruko Takano‐Yamamoto   +14 more
doaj   +1 more source

Maturation of Circulatory Responses to Methionine-Enkephalin [PDF]

Pediatric Research, 1983
The cardiovascular and respiratory effects of the naturally occurring endogenous opiate, methionine-enkephalin, were studied in 23 fetal sheep, five newborn lambs, 15 pregnant sheep, and four nonpregnant ewes. The opiate peptide produced dose-dependent decreases in heart rate and blood pressure in fetal and neonatal lambs but increased heart rate and ...
Abraham M. Rudolph, Edmund F. LaGamma, Joseph Itskovitz   +2 more
openaire   +3 more sources

Methionine-enkephalin and leucine-enkephalin in human sympathoadrenal system and pheochromocytoma. [PDF]

Journal of Clinical Investigation, 1982
To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with ...
Hiroo Imura, Shozo Li, Kazuwa Nakao, Hitoshi Ohtsuki, Takaaki Yoshimasa   +4 more
openaire   +2 more sources