Results 61 to 70 of about 110,810 (218)

Electromembrane extraction of peptides based on charge, hydrophobicity, and size – A large‐scale fundamental study of the extraction window

Journal of Separation Science, Volume 47, Issue 15, August 2024.
This study investigated the capability of electromembrane extraction (EME) as a general technique for peptides, by extracting complex pools of peptides comprising in total of 5953 different substances, varying in size from seven to 16 amino acids. Electromembrane extraction was conducted from a sample adjusted to pH 3.0 and utilized a liquid membrane ...
Torstein Kige Rye, Chien‐Yun Lee, Andreas Zellner, Sara Haglund Moen, Samira Dowlatshah, Trine Grønhaug Halvorsen, Stig Pedersen‐Bjergaard, Frederik André Hansen   +7 more
wiley   +1 more source

Carbon turnover in the water-soluble protein of the adult human lens. [PDF]

, 2013
PurposeHuman eye lenses contain cells that persist from embryonic development. These unique, highly specialized fiber cells located at the core (nucleus) of the lens undergo pseudo-apoptosis to become devoid of cell nuclei and most organelles. Ostensibly
Buchholz, Bruce A, Falso, Miranda JS, FitzGerald, Paul G, Hammock, Bruce D, Lango, Jozsef, Nambiar, Krishnan P, Rocke, David M, Stewart, Daniel N   +7 more
core   +1 more source

Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. [PDF]

, 2010
Despite abundant expression of DNA methyltransferases (Dnmts) in brain, the regulation and behavioral role of DNA methylation remain poorly understood. We found that Dnmt3a expression was regulated in mouse nucleus accumbens (NAc) by chronic cocaine use ...
Bolaños, Carlos A, Covington, Herbert E, Dietz, David M, Dumitriu, Dani, Eisch, Amelia J, Fan, Gouping, Feng, Jian, Hollis, Fiona, Hurd, Yasmin L, Iñiguez, Sergio D, Kabbaj, Mohamed, Koo, Ja Wook, LaPlant, Quincey, Maze, Ian, Morrison, John H, Mouzon, Ezekiell, Nestler, Eric J, Neve, Rachael L, Noonan, Michele A, Oosting, Ronald S, Ren, Yanhua, Renthal, William, Vialou, Vincent, Wang, Hui, Warren, Brandon L, Watts, Emily L, Xiao, Guanghua   +26 more
core   +3 more sources

Radiation‐Induced Molecular Processes in DNA: A Perspective on Gas‐Phase Interaction Studies

Chemistry – A European Journal, Volume 30, Issue 38, July 5, 2024.
This perspective explores the technical developments towards crossed‐beam studies of ionizing radiation with mass‐selected and conformationally pure beams of oligonucleotide ions. It reviews key developments in the field and highlights challenges.
Thomas Schlathölter, Jean‐Christophe Poully   +1 more
wiley   +1 more source

Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]

, 2004
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core  

Pro-opiomelanocortin co-localizes with corticotropin-releasing factor in axon terminals of the noradrenergic nucleus locus coeruleus [PDF]

, 2006
We previously demonstrated that the opioid peptide, enkephalin, and corticotropin-releasing factor (CRF) are occasionally co-localized in individual axon terminals but more frequently converge on common dendrites in the locus coeruleus (LC).
Glaser, Julia D., Magtoto, Ronaldo, Reyes, Beverly A.S., van Bockstaele, Elisabeth K.   +3 more
core   +2 more sources

Human epicardial fat has a beige profile and contains higher type 2 innate lymphoid cells than subcutaneous fat

Obesity, Volume 32, Issue 7, Page 1302-1314, July 2024.
Abstract Objective Epicardial adipose tissue (EAT) is a visceral fat that has been associated with coronary artery disease and atrial fibrillation. Previous work has revealed that EAT exhibits beige features. Methods First, a new pan‐genomic microarray analysis was performed on previously collected paired human EAT and thoracic subcutaneous AT (thSAT ...
Elisa Doukbi, Patricia Ancel, Anne Dutour, Astrid Soghomonian, Shaista Ahmed, Victoria Castejon, Christelle Piperoglou, Vlad Gariboldi, Marien Lenoir, Eric Lechevallier, Bastien Gondran‐Tellier, Romain Boissier, Mikael Ebbo, Frédéric Vély, Bénédicte Gaborit   +14 more
wiley   +1 more source

Mechanism of action of pseudopteroxazole and pseudopterosin G: Diterpenes from marine origin

PROTEOMICS, Volume 24, Issue 10, May 2024.
Abstract Pseudopteroxazole (Ptx) and the pseudopterosins are marine natural products with promising antibacterial potential. While Ptx has attracted interest for its antimycobacterial activity, pseudopterosins are active against several clinically relevant pathogens. Both compound classes exhibit low cytotoxicity and accessibility to targeted synthesis,
Niklas B. M. Janzing, Christoph H. R. Senges, Pascal Dietze, Bradley Haltli, Douglas H. Marchbank, Russell G. Kerr, Julia E. Bandow   +6 more
wiley   +1 more source

Comparative analysis of the effects of different purification methods on the yield and purity of cow milk extracellular vesicles

Journal of Extracellular Biology, Volume 3, Issue 4, April 2024.
Abstract Isolation of extracellular vesicles (EV) has been developing rapidly in parallel with the interest in EVs. However, commonly utilized protocols may not suit more challenging sample matrixes and could potentially yield suboptimal results. Knowing and assessing the pitfalls of isolation procedure to be used, should be involved to some extent for
Santeri Kankaanpää, Markus Nurmi, Markus Lampimäki, Heidi Leskinen, Anni Nieminen, Anatoliy Samoylenko, Seppo J. Vainio, Sari Mäkinen, Lauri Ahonen, Juha Kangasluoma, Tuukka Petäjä, Sirja Viitala   +11 more
wiley   +1 more source

Oral naltrexone treatment for cholestatic pruritus: A double-blind, placebo-controlled study [PDF]

, 1997
Background and Aims: The efficacy of currently available therapeutic agents for cholestatic pruritus is often disappointing. The aim of this study was to assess the antipruritic effect of naltrexone, an oral opiate receptor antagonist.
Bertolotti, M. (M.), Buuren, H.R. (Henk) van, Hop, W.C.J. (Wim), Sternieri, E. (E.), Vitale, G. (G.), Wolfhagen, F.H.J. (Franciscus)   +5 more
core   +3 more sources