Results 91 to 100 of about 36,339 (224)
CNS Active O-Linked Glycopeptides that Penetrate the BBB
Frontiers in Chemistry, 2015 Naturally occurring glycopeptides and glycoproteins play important roles in biological processes. Glycosylation is one of the most common post-translational modifications in vivo.
Evan M Jones, Robin ePolt
doaj +1 more source
On the History of Hepatic Vein Catheterization
Liver International, Volume 46, Issue 9, September 2026.ABSTRACT Hepatic vein catheterization (HVC) in man was first performed 80 years ago in the wake of right‐sided heart catheterization. Several new methods, recognitions and concepts followed, especially the indirect Fick‐method for determination of splanchnic blood flow. Five years passed before pressure measurements were performed and routine HVCs were
Jens Henrik Henriksen +2 more
wiley +1 more source
Venom‐Derived Bioactive Peptides: From Toxins to Therapeutics
Advanced Therapeutics, Volume 9, Issue 8, August 2026.Venomics → Target Identification → Peptide Optimization → Therapeutic Translation Bioactive venom peptides targeting ion channels, enzymes, and receptors drive the development of next‐generation precision therapeutics. ABSTRACT Venoms are complex biochemical mixtures composed of diverse bioactive components, including proteins, enzymes, small molecules,
Eldho Sabu, Othman Al Musaimi
wiley +1 more source
Autism Research, Volume 19, Issue 8, August 2026.ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction, restricted interests, and repetitive behaviors. In addition to these core behavioral symptoms, gastrointestinal (GI) disorders are frequently reported, ranging from severe constipation to diarrhea.
Baptiste Ganachaud +9 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.A hydroalcoholic extract from the renewable periderm of Pinus pinea is characterized through integrated phytochemical, biological and elemental analyses. The extract exhibits a phenolic‐rich composition, significant antioxidant activity and preliminary protection against oxidative stress in SH‐SY5Y cells, while elemental profiling indicates low levels ...
Vlad Sebastian Popescu +6 more
wiley +1 more source
, 1998 In this study, the stability in and transport across a cell culture model of the blood-brain barrier (BBB) is investigated for leucine-enkephalin (Leu-enkephalin) and four 4-imidazolidinone prodrugs of Leu-enkephalin. The results show that Leu-enkephalin
G.J Friis +9 more
core +1 more source
Met-enkephalin immunoreactivity in blood platelets
, 1982 Picogram amounts (50-150 pg/mg protein) of immunoreactive met-enkephalin material (met-enkephalin in IR) were detected by radioimmunoassay in human, rat and rabbit platelets.
A. M. Cesura +4 more
core +1 more source
AnimalsThis study examined the effects of acute restraint stress in the presence or absence of naltrexone on the circulating concentrations of insulin, glucose, Met-enkephalin and corticosterone in 14-week-old chickens [design: 2 sex × 2 stress/non-stress × 2 +/
Colin G. Scanes +2 more
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The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential
Frontiers in Molecular Neuroscience, 2017 Temporal lobe epilepsy is considered to be one of the most common and severe forms of focal epilepsies. Patients often develop cognitive deficits and emotional blunting along the progression of the disease.
Johannes Burtscher, Christoph Schwarzer
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Neuropharmacological actions of enkephalin after systemic administration
, 1976 A pentapeptide, methionine-enkephalin, which interacts with opiate receptors in the brain, was found to markedly potentiate the behavioral effects of DOPA when administered intraperitoneally into mice.
Coy, David H +5 more
core +1 more source