Results 91 to 100 of about 33,668 (227)

Immunocytochemical evidence for the presence of Met-enkephalin and Leu-enkephalin in distinct neurons in the brain of the elasmobranch fish Scyliorhinus canicula. [PDF]

, 1994
Immunohistochemical methods have been used to investigate the distribution of various opioid peptides derived from mammalian proenkephalin in the central nervous system of Scyliorhinus canicula.
H. Vaudry, M. Vallarino, C. Bucharles, Hubert Vaudry, Mauro Vallarino, FACCHINETTI, Fabio, Fabio Facchinetti, Christine Bucharles   +7 more
core   +1 more source

CNS Active O-Linked Glycopeptides that Penetrate the BBB

Frontiers in Chemistry, 2015
Naturally occurring glycopeptides and glycoproteins play important roles in biological processes. Glycosylation is one of the most common post-translational modifications in vivo.
Evan M Jones, Robin ePolt
doaj   +1 more source

Mapping the Substrate Specificity Landscape of PAD2 and PAD4 Enzymes

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Protein citrullination, driven by peptidyl arginine deiminases (PAD2, PAD4), is linked to multiple diseases. Using a combinatorial peptide library and advanced mass spectrometry, we reveal distinct substrate selectivity profiles of PAD2 and PAD4. While PAD2 broadly citrullinates arginine‐containing peptides, PAD4 is highly sequence‐restricted, with ...
Adina Borbély, Arnold Steckel, Dávid Papp, Domonkos Pál, Katalin Uray, Viktória Goldschmidt Gőz, Gitta Schlosser   +6 more
wiley   +1 more source

Interaction of enkephalin and caerulein on guinea pig small intestine [PDF]

, 1983
This is a report on the effect of caerulein and methionine-enkephalin interaction on mechanical contraction and acetylcholine release in vitro. The ability of enkephalin to relax caerulein-induced contractions and the manner in which the caerulein dose ...
M. L. Youther, W. M. Yau, P. F. Lingle
core   +1 more source

UHPLC–MS based metabolomics study of the ErZhi formula on skeletal muscle against osteosarcopenia focusing on energy metabolism

Animal Models and Experimental Medicine, Volume 9, Issue 6, Page 1235-1247, June 2026.
ErZhi formula (EZF) is composed of Ligustri Lucidi Fructus (LLF) and Ecliptae herba (EH). Ovariectomized (OVX) and sham rats received 12‐week intragastric treatment with EZF, alendronate, and vehicle saline. Gastrocnemius tissues were harvested to systematically evaluate pharmacodynamic changes in skeletal muscle morphology, mitochondrial ...
Yuqing Pang, Ningning Li, Yujie Ding, Shuzhen Hou, Jing Liu, Xiuxue Liu, Erwei Liu, Xiaopeng Chen   +7 more
wiley   +1 more source

Cardiac synthesis, processing, and coronary release of enkephalin-related peptides [PDF]

, 2000
Although preproenkephalin mRNA is abundant in the heart, the myocardial synthesis and processing of proenkephalin is largely undefined. Isolated working rat hearts were perfused to determine the rate of myocardial proenkephalin synthesis, its processing ...
Edward G. Lakatta, Harold A. Spurgeon, James L. Caffrey, Salvatore Pepe, Antoine Younès, Barbara A. Barron   +5 more
core   +1 more source

Sentience in cephalopod molluscs: an updated assessment

Biological Reviews, Volume 101, Issue 3, Page 1311-1333, June 2026.
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell, Heather Browning, Andrew Crump, Charlotte C. Burn, Jonathan Birch   +4 more
wiley   +1 more source

Advantages of Alkali Metal Adduct Formation in Cyclic Ion Mobility‐Mass Spectrometry of O‐Methylated Cyclodextrin Isomers—Separation and Crossring Fragmentation

Chemistry–Methods, Volume 6, Issue 6, June 2026.
Cyclic ion mobility–tandem mass spectrometry (cIM‐MS/MS) enables rapid differentiation of O‐methylated cyclodextrin (MeCD) regioisomers. The method separates 2,3‐ and 2,6‐DIMEB (heptakis‐2,3‐ and ‐2,6‐di‐O‐methyl‐β‐cyclodextrins) and identifies them via characteristic crossring fragmentation.
Péter Soma Szakály, Arnold Steckel, Dávid Papp, Erzsébet Varga, Gitta Schlosser   +4 more
wiley   +1 more source

In the African Lungfish Met-Enkephalin and Leu-Enkephalin Are Derived from Separate Genes: Cloning of a Proenkephalin cDNA [PDF]

, 2000
International audienceA full-length proenkephalin cDNA (accession number: AF232670) was cloned from an African lungfish (Protopterus annectens) brain cDNA library.
Sollars, Cristina, Lihrmann, Isabelle, Danielson, Phillip, Vaudry, Hubert, Vallarino, Mauro, Dores, Robert, Lee, Jenny   +6 more
core   +1 more source

The lipolytic activity of met-enkephalin, leu-enkephalin, morphine, methadone and naloxone in human adipose tissue [PDF]

, 1981
Met-enkephalin and Leu-enkephalin lipolytic activity in human omental adipose tissue is compared with that of morphine, methadone and naloxone. Met- and leu-enkephalin exhibited lipolytic action similar to that of morphine but unlike that of methadone ...
NENCINI, Paolo, PAROLI, Eugenio
core