Results 71 to 80 of about 47,172 (213)
High‐Throughput N‐Glycan Analysis by IR‐MALDESI With a 1.5‐kHz Pulsed Mid‐IR Laser
Journal of Mass Spectrometry, Volume 61, Issue 5, May 2026.ABSTRACT Infrared matrix‐assisted laser desorption electrospray ionization (IR‐MALDESI) is a laser‐based, hybrid ionization source for mass spectrometry, enabling both mass spectrometry imaging (MSI) and high‐throughput screening (HTS). In this work, a 2.2‐ns, 2.72‐μm laser, operating at 1.5 kHz, was integrated into the IR‐MALDESI platform to evaluate ...
Seth M. Eisenberg +5 more
wiley +1 more source
New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]
, 1984 The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Berlit, Peter +3 more
core +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
MedComm, Volume 7, Issue 5, May 2026.Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source
Frontiers in Psychiatry, 2018 Adolescent binge drinking is associated with an increased risk of substance use disorder, but how ethanol affects the central levels of endogenous opioid peptides is still not thoroughly investigated.
Linnea Granholm +2 more
doaj +1 more source
Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management
MedComm, Volume 7, Issue 5, May 2026.The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang +12 more
wiley +1 more source
Generalized-ensemble Monte carlo method for systems with rough energy landscape
, 1997 We present a novel Monte Carlo algorithm which enhances equilibrization of low-temperature simulations and allows sampling of configurations over a large range of energies.
A. M. Ferrenberg +20 more
core +1 more source
A Stepwise Approach to 1,4,10,13‐Tetraaza‐18‐Crown‐6 Ether
ChemistryOpen, Volume 15, Issue 5, May 2026.A two‐step synthetic strategy to tetraaza‐18‐crown‐6 was developed to overcome the low yield of the conventional one‐step method. Optimized conditions significantly suppressed formation of the undesired nine‐membered ring. A three‐fold increase in yield of the macrocyclization step was obtained, or two‐fold when column chromatography was avoided. A two‐
Pieter Troosters +3 more
wiley +1 more source
Frontiers in Neuroanatomy, 2011 Dopaminergic signaling within the basal ganglia has classically been thought to occur within two distinct neuronal pathways; the direct striatonigral pathway which contains the dopamine D1 receptor and the neuropeptides dynorphin and substance P, and the
Melissa L. Perreault +7 more
doaj +1 more source
Opioids in breast cancer: Between analgesia and modulation of tumour progression
British Journal of Pharmacology, Volume 183, Issue 9, Page 1727-1746, May 2026.Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun +2 more
wiley +1 more source
Multi-Overlap Simulations for Transitions between Reference Configurations
, 2003 We introduce a new procedure to construct weight factors, which flatten the probability density of the overlap with respect to some pre-defined reference configuration.
A. Mitsutake +28 more
core +1 more source