Results 71 to 80 of about 37,089 (225)
RELEASE OF VASOPRESSIN BY ENKEPHALIN [PDF]
Leu‐enkephalin, its stable analogue [D‐Ala2‐D‐Leu5]‐enkephalin and the C‐fragment of lipotropin (β endorphin) injected intravenously in the rat produced anti‐diuretic responses which were inhibited reversibly by naloxone. It was shown for Leu‐enkephalin that injection into the cerebral ventricles was at least ten times more effective than intravenous ...
G W, Bisset, H S, Chowdrey, W, Feldberg
openaire +2 more sources
A Comparative Study of MALDI MSI Versus DESI MSI Applied to Questioned Document Examination
ABSTRACT Rationale In forensic investigations, questioned document examination (QDE) provides critical information for document authentication and the detection of forgeries. Conventional QDE approaches often require separate analyses of inks and of any potential fingerprints.
Veronika Tibljas +4 more
wiley +1 more source
Glia of () naïve animals or () vehicle-treated animals fed the alcohol and high-fat diet. Note the presence of staining for human HSV-1 protein in DRG of animals given the () HSV-β-gal and () HSV-ENK vector treatments.
Yong Ren (86476) +7 more
core +1 more source
Functionalization of Peptides via Radical Arylation
Radical chemistry has only rarely been applied to peptide functionalization. This short review highlights radical arylation as an attractive approach to access functionalized peptides under mild, biocompatible conditions without protecting groups.
Daniel R. Troeger, Markus R. Heinrich
wiley +1 more source
Enkephalin-dopamine interactions in behavioral arousal
1. 1. Central injection of a long lasting enkephalin analog (D-Ala2-leuo-enkephalin-amide) produced a syndrome of stereotyped motor activity.2. 2. This activation syndrome was significantly reduced by two dopamine (DA) blockers (pimozide, fluspirilene ...
Katz, Richard J., Carroll, Bernard J.
core +1 more source
Dopaminergic signaling within the basal ganglia has classically been thought to occur within two distinct neuronal pathways; the direct striatonigral pathway which contains the dopamine D1 receptor and the neuropeptides dynorphin and substance P, and the
Melissa L. Perreault +7 more
doaj +1 more source
Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao +10 more
wiley +1 more source
At pancreas. . Diet-induced pancreatitis and application of vehicle. . Diet-induced pancreatitis and application of HSV-β-gal as HSV vector control. . Pancreas from animals given diet and application of HSV-ENK. There was no significant positive staining
Yong Ren (86476) +7 more
core +1 more source
Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source
CNS Active O-Linked Glycopeptides that Penetrate the BBB
Naturally occurring glycopeptides and glycoproteins play important roles in biological processes. Glycosylation is one of the most common post-translational modifications in vivo.
Evan M Jones, Robin ePolt
doaj +1 more source

