Results 71 to 80 of about 37,089 (225)

RELEASE OF VASOPRESSIN BY ENKEPHALIN [PDF]

open access: yesBritish Journal of Pharmacology, 1978
Leu‐enkephalin, its stable analogue [D‐Ala2‐D‐Leu5]‐enkephalin and the C‐fragment of lipotropin (β endorphin) injected intravenously in the rat produced anti‐diuretic responses which were inhibited reversibly by naloxone. It was shown for Leu‐enkephalin that injection into the cerebral ventricles was at least ten times more effective than intravenous ...
G W, Bisset, H S, Chowdrey, W, Feldberg
openaire   +2 more sources

A Comparative Study of MALDI MSI Versus DESI MSI Applied to Questioned Document Examination

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 19, 15 October 2026.
ABSTRACT Rationale In forensic investigations, questioned document examination (QDE) provides critical information for document authentication and the detection of forgeries. Conventional QDE approaches often require separate analyses of inks and of any potential fingerprints.
Veronika Tibljas   +4 more
wiley   +1 more source

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model-5

open access: yes, 2011
Glia of () naïve animals or () vehicle-treated animals fed the alcohol and high-fat diet. Note the presence of staining for human HSV-1 protein in DRG of animals given the () HSV-β-gal and () HSV-ENK vector treatments.
Yong Ren (86476)   +7 more
core   +1 more source

Functionalization of Peptides via Radical Arylation

open access: yesChemBioChem, Volume 27, Issue 19, 14 October 2026.
Radical chemistry has only rarely been applied to peptide functionalization. This short review highlights radical arylation as an attractive approach to access functionalized peptides under mild, biocompatible conditions without protecting groups.
Daniel R. Troeger, Markus R. Heinrich
wiley   +1 more source

Enkephalin-dopamine interactions in behavioral arousal

open access: yes, 1979
1. 1. Central injection of a long lasting enkephalin analog (D-Ala2-leuo-enkephalin-amide) produced a syndrome of stereotyped motor activity.2. 2. This activation syndrome was significantly reduced by two dopamine (DA) blockers (pimozide, fluspirilene ...
Katz, Richard J., Carroll, Bernard J.
core   +1 more source

The dopamine D1-D2 receptor heteromer in striatal medium spiny neurons: evidence for a third distinct neuronal pathway in basal ganglia

open access: yesFrontiers in Neuroanatomy, 2011
Dopaminergic signaling within the basal ganglia has classically been thought to occur within two distinct neuronal pathways; the direct striatonigral pathway which contains the dopamine D1 receptor and the neuropeptides dynorphin and substance P, and the
Melissa L. Perreault   +7 more
doaj   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao   +10 more
wiley   +1 more source

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model-9

open access: yes, 2011
At pancreas. . Diet-induced pancreatitis and application of vehicle. . Diet-induced pancreatitis and application of HSV-β-gal as HSV vector control. . Pancreas from animals given diet and application of HSV-ENK. There was no significant positive staining
Yong Ren (86476)   +7 more
core   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

open access: yesAdvanced Science, Volume 13, Issue 57, 14 October 2026.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer   +9 more
wiley   +1 more source

CNS Active O-Linked Glycopeptides that Penetrate the BBB

open access: yesFrontiers in Chemistry, 2015
Naturally occurring glycopeptides and glycoproteins play important roles in biological processes. Glycosylation is one of the most common post-translational modifications in vivo.
Evan M Jones, Robin ePolt
doaj   +1 more source

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