Results 61 to 70 of about 37,089 (225)

Improved Serotonin Measurement With Fast‐Scan Cyclic Voltammetry: Analysis of Electrode Fouling by Fluoxetine in Live Brain Tissue

open access: yesAnalysis &Sensing, Volume 6, Issue 6, November 2026.
Fluoxetine (Prozac) is a drug that is useful for treating depression and for studying serotonin system function in live brain tissue. Unfortunately, the use of fluoxetine tends to foul electrodes when using fast‐scan cyclic voltammetry. In this work, we evaluated an extended serotonin waveform as a useful approach for mitigating fouling by fluoxetine ...
Chase Stucky   +7 more
wiley   +1 more source

Neuropharmacological actions of enkephalin after systemic administration

open access: yes, 1976
A pentapeptide, methionine-enkephalin, which interacts with opiate receptors in the brain, was found to markedly potentiate the behavioral effects of DOPA when administered intraperitoneally into mice.
Coy, David H   +5 more
core   +1 more source

Microbial deamination of peptides and proteins as a source of persistent marine dissolved organic matter

open access: yesLimnology and Oceanography Letters, Volume 11, Issue 6, November 2026.
Abstract Refractory dissolved organic nitrogen is a major component of the ocean's nitrogen pool, yet the mechanisms producing and preserving it remain poorly understood. Here, we show that deaminated peptides (DAPs), derived from microbial processing of proteinaceous material, are ubiquitous across oxygenated marine environments—from productive ...
Pauline L. Martinot   +3 more
wiley   +1 more source

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model-3

open access: yes, 2011
Inimal or no staining is seen in pancreas of () naïve and () control animals with alcohol and high-fat diet induced pancreatitis. . Met-ENK expression was significantly increased in the pancreas of HSV-ENK-treated animals fed the same diet compared to ...
Yong Ren (86476)   +7 more
core   +1 more source

Spatial relationship between the c-Fos distribution and enkephalinergic, substance P, and tyrosine hydroxylase innervation fields after acute treatment with neuroleptics olanzapine, amisulpride, quetiapine, and aripiprazole in the rat septum

open access: yesEndocrine Regulations, 2019
Objective. The aim of the present study was to demonstrate the spatial relationship between the c-Fos immunoreactive cells elicited by an acute treatment with neuroleptics including amisulpride (AMI), olanzapine (OLA), quetiapine (QUE), and aripiprazole (
Kiss Alexander, Osacka Jana
doaj   +1 more source

Gastric Cancer: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, Diagnosis, and Management

open access: yesMedComm, Volume 7, Issue 11, November 2026.
This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin   +6 more
wiley   +1 more source

Hepatoprotective Effects of Met-enkephalin on Acetaminophen-Induced Liver Lesions in Male CBA Mice

open access: yesMolecules, 2014
Recent histopathological investigations in patients with hepatitis suggested possible involvement of Met-enkephalin and its receptors in the pathophysiology of hepatitis.
Roko Martinić   +9 more
doaj   +1 more source

Opioid Modulation of Major Neurotransmitter Systems: Acute, Chronic, and Withdrawal Effects

open access: yesEuropean Journal of Neuroscience, Volume 64, Issue 9, November 2026.
Opioids are widely used but also frequently misused drugs that affect multiple neurotransmitter systems, including dopaminergic, glutamatergic, GABAergic, serotonergic, and cholinergic pathways. Opioid‐induced neuroadaptations depend on the duration of drug exposure, with distinct changes also emerging following drug discontinuation.
Daniela Novakova   +2 more
wiley   +1 more source

Enkephalin suppresses afferent cochlear neurotransmission.

open access: yes, 1993
The effects of enkephalin and naloxone, applied iontophoretically, were tested on induced firing activity of the afferent dendrites on inner hair cells in the guinea pig. Enkephalin strongly depresses the depolarizing effect of N-methyl-D-aspartate (NMDA)
Bürki C, Felix D, Ehrenberger K
core   +1 more source

Episodic Ethanol Exposure in Adolescent Rats Causes Residual Alterations in Endogenous Opioid Peptides

open access: yesFrontiers in Psychiatry, 2018
Adolescent binge drinking is associated with an increased risk of substance use disorder, but how ethanol affects the central levels of endogenous opioid peptides is still not thoroughly investigated.
Linnea Granholm   +2 more
doaj   +1 more source

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