Results 81 to 90 of about 37,089 (225)

Met-enkephalin immunoreactivity in blood platelets

, 1982
Picogram amounts (50-150 pg/mg protein) of immunoreactive met-enkephalin material (met-enkephalin in IR) were detected by radioimmunoassay in human, rat and rabbit platelets.
A. M. Cesura, G. B. Picotti, A.E. Panerai, P. Mantegazza, A.M. Di Giulio   +4 more
core   +1 more source

Reversal of Chronic Stress‐Induced Inflammaging by Bazi Bushen Formula Through AMPK‐Sirtuins Axis Activation and Myeloid Reset

Exploration, Volume 6, Issue 5, October 2026.
Chronic stressors trigger systemic immune remodeling marked by myeloid expansion and lymphoid suppression, and this immune imbalance subsequently drives tissue pathology through proinflammatory signaling and senescence amplification, with the lung and kidney confirmed as the most vulnerable target organs.
Mengnan Li, Zheming Chen, Lu Wang, Zixuan Wang, Shixiong Zhang, Kunxu Niu, Xiaogang Shen, Xuan Lu, Runtao Zhang, Yuning Jiang, Yawen Li, Yi Dai, Xiyang Tang, Bin Hou, Min Shi, Xiaoya Wang, Zhifang Guo, Xingyu Xing, Ning Kang, Hongrong Li, Tianyu Kang, Evelyne Bischof, Yunlong Hou, Zhenhua Jia   +23 more
wiley   +1 more source

Cardiac synthesis, processing, and coronary release of enkephalin-related peptides

, 2000
Although preproenkephalin mRNA is abundant in the heart, the myocardial synthesis and processing of proenkephalin is largely undefined. Isolated working rat hearts were perfused to determine the rate of myocardial proenkephalin synthesis, its processing ...
Edward G. Lakatta, Harold A. Spurgeon, James L. Caffrey, Salvatore Pepe, Antoine Younès, Barbara A. Barron   +5 more
core   +1 more source

The Role of Ultra‐Low‐Dose Naloxone as an Additive in Anesthesia and Nerve Block: A Systematic Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims In anesthesia and analgesia, opioids alone or in combination with local anesthetics (bupivacaine, lidocaine, and ropivacaine) have been investigated to prolong peripheral nerve blocks. Ultra‐low‐dose naloxone administration in local anesthetic solutions could lengthen sensory and motor blocks through enhanced opioid effects
Mohammadjavad Mehrabanian, Behrang Nooralishahi, Mehdi Dehghani Firoozabadi, Mohammad Sahebjam, Yekta Ghane, Homayoun Pishraft‐Sabet, Nazila Heidari, Akbar Shafiee   +7 more
wiley   +1 more source

Amino Acids and Peptides. XXIII. Leu-Enkephalin Analogs Containing a Fluorinated Amino Acid at Position 2, 4 or 5. [PDF]

, 1994
Fluorinated analogs of Leu-enkephalin were synthesized by the solution method and the solid-phase method. The synthetic peptides were examined for opioid activities on mouse vas deferens and guinea pig ileum. Among the synthetic peptides, [D-Ala2, Leu(F3)
YAMAMOTO, Yoshihiro, Kaoru NAKAO, KOBAYASHI, Yoshiro, Takeo TAGUCHI, TAGUCHI, Takeo, NAKAO, Kaoru, Yoshihiro YAMAMOTO, KANETO, Hiroshi, MAEDA, Mitsuko, KAWASAKI, Koichi, SHIMOKAWA, Kazuhiro, Hiroshi KANETO, Kazuhiro SHIMOKAWA, Yoshiro KOBAYASHI, TAKAHASHI, Masakatsu, Koichi KAWASAKI, Masakatsu TAKAHASHI, Mitsuko MAEDA   +17 more
core   +2 more sources

Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress in mice

eLife
Enkephalins are opioid peptides that modulate analgesia, reward, and stress. In vivo detection of enkephalins remains difficult due to transient and low endogenous concentrations and inherent sequence similarity.
Marwa O Mikati, Petra Erdmann-Gilmore, Rose Connors, Sineadh M Conway, Jim Malone, Justin Woods, Robert W Sprung, Reid R Townsend, Ream Al-Hasani   +8 more
doaj   +1 more source

The lipolytic activity of met-enkephalin, leu-enkephalin, morphine, methadone and naloxone in human adipose tissue

, 1981
Met-enkephalin and Leu-enkephalin lipolytic activity in human omental adipose tissue is compared with that of morphine, methadone and naloxone. Met- and leu-enkephalin exhibited lipolytic action similar to that of morphine but unlike that of methadone ...
NENCINI, Paolo, PAROLI, Eugenio
core  

Effects of Restraint Stress on Circulating Corticosterone and Met Enkephalin in Chickens: Induction of Shifts in Insulin Secretion and Carbohydrate Metabolism

Animals
This study examined the effects of acute restraint stress in the presence or absence of naltrexone on the circulating concentrations of insulin, glucose, Met-enkephalin and corticosterone in 14-week-old chickens [design: 2 sex × 2 stress/non-stress × 2 +/
Colin G. Scanes, Krystyna Pierzchała-Koziec, Alina Gajewska   +2 more
doaj   +1 more source

The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential

Frontiers in Molecular Neuroscience, 2017
Temporal lobe epilepsy is considered to be one of the most common and severe forms of focal epilepsies. Patients often develop cognitive deficits and emotional blunting along the progression of the disease.
Johannes Burtscher, Christoph Schwarzer
doaj   +1 more source

Induction of differentiation increases Met5-enkephalin and Leu5- enkephalin content in NG108-15 hybrid cells: an immunocytochemical and biochemical analysis

, 1983
Regulation of cellular content of the endogenous opioid peptides Met5- enkephalin and Leu5-enkephalin was investigated in neuroblastoma X glioma hybrid cells NG108-15 grown in both serum-supplemented and serum- free defined media.
SR Childers, DC U'Prichard, KM Braas
core   +1 more source