Results 81 to 90 of about 33,668 (227)
Isolation and structure of pro-methionine-enkephalin: Potential enkephalin precursor from porcine hypothalamus [PDF]
A hexapeptide that we have named pro-methionine-enkephalin has been isolated from acid extracts of porcine hypothalami and found to have the amino acid sequence H-Tyr-Gly-Gly-Phe-Met(O)-Arg-OH.
Coy, David H +4 more
core +1 more source
Adolescent binge drinking is associated with an increased risk of substance use disorder, but how ethanol affects the central levels of endogenous opioid peptides is still not thoroughly investigated.
Linnea Granholm +2 more
doaj +1 more source
This study evaluates the clinical efficacy of acupuncture as an adjunct therapy in the management of intrapartum bovine uterine torsion. In a randomised field trial involving 93 cows, the effects of acupuncture on cervical status and delivery outcomes were assessed.
Eva Maria Erteld +3 more
wiley +1 more source
BmK-YA, an Enkephalin-Like Peptide in Scorpion Venom [PDF]
By screening extracts of venom from the Asian scorpion Buthus martensii Karsch (BmK) for their abilities to activate opioid receptors, we have identified BmK-YA, an amidated peptide containing an enkephalin-like sequence. BmK-YA is encoded by a precursor
Liang, Xinmiao +7 more
core +1 more source
A structure of the flavin‐dependent single‐component tryptophan halogenase AetF bound to the non‐native tricyclic substrate tryptoline reveals a binding pose analogous to l‐tryptophan that directs C6‐first halogenation. Product analysis identifies 6,8‐dibromotryptoline as the final product.Flavin‐dependent halogenases (FDHs) offer a biocatalytic route ...
Simon Bork +3 more
wiley +1 more source
Modulation of cholinergic neurotransmission in airways by enkephalin [PDF]
We compared the effects of methionine enkephalin and leucine enkephalin on contractions of isolated canine tracheal smooth muscle strips induced by field electrical stimulation (ES) and exogenous acetylcholine (approximately 10(-5) M).
J. A. Russell, E. J. Simons
core +1 more source
CIRCULATING CATECHOLAMINES, MELATONIN AND ENKEPHALIN IN MAN FOLLOWING ADMINISTRATION OF A MET-ENKEPHALIN ANALOG [PDF]
The met-enkephalin analogue, D-Ala2-MePhe4-met-enkephalin-(C)-ol (DAMME), was given i.v. to 6 normal subjects. Elevations in plasma prolactin and growth hormone (GH) occurred in association with significant falls in plasma epinephrine and norepinephrine.
Grossman, Ashley +5 more
core +2 more sources
Dopaminergic signaling within the basal ganglia has classically been thought to occur within two distinct neuronal pathways; the direct striatonigral pathway which contains the dopamine D1 receptor and the neuropeptides dynorphin and substance P, and the
Melissa L. Perreault +7 more
doaj +1 more source
Liver‐ and Immune‐Enriched Molecular Signatures Associated With Mortality in Older Adults
Untargeted plasma proteomics and metabolomics identified molecular signatures associated with all‐cause mortality in older adults. A liver‐enriched proteomic profile was associated with mortality risk in the ILAS cohort and showed consistent associations in an independent validation cohort, supporting circulating proteomic profiles for mortality risk ...
Yi‐Long Huang +5 more
wiley +1 more source
Just as fingerprints reveal identity, spectroscopic fingerprints reveal molecular secrets. In this article, we show parts of the unique fingerprint of the sulfur–aromatic interaction. By measuring how this force alters the electronic structure of gas‐phase peptides, we provide a fundamental understanding of interactions that give insights into the ...
Laura Pille +12 more
wiley +1 more source

