Results 81 to 90 of about 33,668 (227)

Isolation and structure of pro-methionine-enkephalin: Potential enkephalin precursor from porcine hypothalamus [PDF]

open access: yes, 1979
A hexapeptide that we have named pro-methionine-enkephalin has been isolated from acid extracts of porcine hypothalami and found to have the amino acid sequence H-Tyr-Gly-Gly-Phe-Met(O)-Arg-OH.
Coy, David H   +4 more
core   +1 more source

Episodic Ethanol Exposure in Adolescent Rats Causes Residual Alterations in Endogenous Opioid Peptides

open access: yesFrontiers in Psychiatry, 2018
Adolescent binge drinking is associated with an increased risk of substance use disorder, but how ethanol affects the central levels of endogenous opioid peptides is still not thoroughly investigated.
Linnea Granholm   +2 more
doaj   +1 more source

Can Acupuncture Be Effective in Treating Insufficiently Dilated Cervix Following Intrapartum Uterine Torsion in Cows?

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study evaluates the clinical efficacy of acupuncture as an adjunct therapy in the management of intrapartum bovine uterine torsion. In a randomised field trial involving 93 cows, the effects of acupuncture on cervical status and delivery outcomes were assessed.
Eva Maria Erteld   +3 more
wiley   +1 more source

BmK-YA, an Enkephalin-Like Peptide in Scorpion Venom [PDF]

open access: yes, 2012
By screening extracts of venom from the Asian scorpion Buthus martensii Karsch (BmK) for their abilities to activate opioid receptors, we have identified BmK-YA, an amidated peptide containing an enkephalin-like sequence. BmK-YA is encoded by a precursor
Liang, Xinmiao   +7 more
core   +1 more source

Structural basis of regioselective double halogenation of the β‐carboline tryptoline by the single‐component halogenase AetF

open access: yesActa Crystallographica Section D, Volume 82, Issue 7, Page 836-844, July 2026.
A structure of the flavin‐dependent single‐component tryptophan halogenase AetF bound to the non‐native tricyclic substrate tryptoline reveals a binding pose analogous to l‐tryptophan that directs C6‐first halogenation. Product analysis identifies 6,8‐dibromotryptoline as the final product.Flavin‐dependent halogenases (FDHs) offer a biocatalytic route ...
Simon Bork   +3 more
wiley   +1 more source

Modulation of cholinergic neurotransmission in airways by enkephalin [PDF]

open access: yes, 1985
We compared the effects of methionine enkephalin and leucine enkephalin on contractions of isolated canine tracheal smooth muscle strips induced by field electrical stimulation (ES) and exogenous acetylcholine (approximately 10(-5) M).
J. A. Russell, E. J. Simons
core   +1 more source

CIRCULATING CATECHOLAMINES, MELATONIN AND ENKEPHALIN IN MAN FOLLOWING ADMINISTRATION OF A MET-ENKEPHALIN ANALOG [PDF]

open access: yes, 1982
The met-enkephalin analogue, D-Ala2-MePhe4-met-enkephalin-(C)-ol (DAMME), was given i.v. to 6 normal subjects. Elevations in plasma prolactin and growth hormone (GH) occurred in association with significant falls in plasma epinephrine and norepinephrine.
Grossman, Ashley   +5 more
core   +2 more sources

The dopamine D1-D2 receptor heteromer in striatal medium spiny neurons: evidence for a third distinct neuronal pathway in basal ganglia

open access: yesFrontiers in Neuroanatomy, 2011
Dopaminergic signaling within the basal ganglia has classically been thought to occur within two distinct neuronal pathways; the direct striatonigral pathway which contains the dopamine D1 receptor and the neuropeptides dynorphin and substance P, and the
Melissa L. Perreault   +7 more
doaj   +1 more source

Liver‐ and Immune‐Enriched Molecular Signatures Associated With Mortality in Older Adults

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
Untargeted plasma proteomics and metabolomics identified molecular signatures associated with all‐cause mortality in older adults. A liver‐enriched proteomic profile was associated with mortality risk in the ILAS cohort and showed consistent associations in an independent validation cohort, supporting circulating proteomic profiles for mortality risk ...
Yi‐Long Huang   +5 more
wiley   +1 more source

Probing the Influence of Sulfur–Aromatic Interactions on the Electronic Structure of Gas‐Phase Peptides

open access: yesChemistry – A European Journal, Volume 32, Issue 23, 16 June 2026.
Just as fingerprints reveal identity, spectroscopic fingerprints reveal molecular secrets. In this article, we show parts of the unique fingerprint of the sulfur–aromatic interaction. By measuring how this force alters the electronic structure of gas‐phase peptides, we provide a fundamental understanding of interactions that give insights into the ...
Laura Pille   +12 more
wiley   +1 more source

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