Results 101 to 110 of about 47,172 (213)

Generalized-ensemble simulations of spin systems and protein systems

open access: yes, 2001
In complex systems such as spin systems and protein systems, conventional simulations in the canonical ensemble will get trapped in states of energy local minima.
Ayori Mitsutake   +32 more
core   +1 more source

Multi-physics Extension of OpenFMO Framework

open access: yes, 2007
OpenFMO framework, an open-source software (OSS) platform for Fragment Molecular Orbital (FMO) method, is extended to multi-physics simulations (MPS). After reviewing the several FMO implementations on distributed computer environments, the subsequent ...
George Maroulis   +11 more
core   +1 more source

Enkephalin-inactivating enzymes.

open access: yesFolia Pharmacologica Japonica, 1993
The inhibitory effects of opioid peptides such as [Met5]-enkephalin and [Met5]-enkephalin-Arg6 on the electrically-evoked contractions of guinea-pig ileum, mouse vas deferens and rat vas deferens were enhanced by aminopeptidase inhibitors such as amastatin and bestatin, a peptidyl dipeptidase A inhibitor like captopril, and endopeptidase-24.11 ...
T, Oka   +5 more
openaire   +3 more sources

Molecular Aspect of Annelid Neuroendocrine system

open access: yes, 2007
Hormonal processes along with enzymatic processing similar to that found in vertebrates occur in annelids. Amino acid sequence determination of annelids precursor gene products reveals the presence of the respective peptides that exhibit high sequence ...
Salzet, M.
core   +1 more source

Enteric neuromodulators and mucus discharge in a fish infected with the intestinal helminth Pomphorhynchus laevis

open access: yesParasites & Vectors, 2015
Background In vertebrates, the presence of enteric worms can induce structural changes to the alimentary canal impacting on the neuroendocrine system, altering the proper functioning of the gastrointestinal tract and affecting the occurrence and relative
Giampaolo Bosi   +3 more
doaj   +1 more source

Strategies to deliver peptide drugs to the brain [PDF]

open access: yes, 2014
Lalatsa, Katerina   +2 more
core   +1 more source

Enkephalins and Pain Modulation: Mechanisms of Action and Therapeutic Perspectives

open access: yesBiomolecules
Enkephalins, a subclass of endogenous opioid peptides, play a pivotal role in pain modulation. Enkephalins primarily exert their effects through opioid receptors located widely throughout both the central and peripheral nervous systems.
Mario García-Domínguez
doaj   +1 more source

Central δ/κ opioid receptor signaling pathways mediate chronic and/or acute suckling-induced LH suppression in rats during late lactation

open access: yesThe Journal of Reproduction and Development
In mammals, secretion of tonic (pulsatile) gonadotropin-releasing hormone (GnRH)/luteinizing hormone (LH) is often suppressed during lactation. Suppression of GnRH/LH pulses in lactating dams is assumed to be caused by suckling stimuli and a chronic ...
Yoshihisa UENOYAMA   +6 more
doaj   +1 more source

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