Results 101 to 110 of about 37,089 (225)

The regional distribution of thyrotropin releasing hormone, LEU-enkephalin, MET-enkephalin, substance P, somatostatin and cholecystokinin in the rat brain and pituitary

open access: yes, 1991
There was no apparent difference in the regional distribution of neuropeptides in the brain of male and female rats. The highest levels of immunoreactive leu-enkephalin, TRH, substance P and somatostatin were found in the hypothalamus, while the striatum
Tang, F, Man, WSY
core   +1 more source

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model-6

open access: yes, 2011
D (T9–10) are shown for week 10. Spinal cord dorsal horn is shown in . Spinal cord lamina X is shown in . Naïve rats have almost no nuclei staining for c-Fos (, ).
Yong Ren (86476)   +7 more
core   +1 more source

Tyr1‑ψ[(Z)CFCH]-Gly2 Fluorinated Peptidomimetic Improves Distribution and Metabolism Properties of Leu-Enkephalin

open access: yes, 2018
Opioid peptides are key regulators in cellular and intercellular physiological responses, and could be therapeutically useful for modulating several pathological conditions.
Ryan A. Altman (1328814)   +6 more
core   +1 more source

Inhibition of peptidases potentiates enkephalin-stimulated contraction of gastric muscle cells

open access: yes, 1991
Cell surface peptidases degrade enkephalins and thereby restrict the number of molecules available to activate receptors. The effects of peptidase inhibitors on degradation of enkephalins and on enkephalin-stimulated contraction of gastric smooth muscle
N. W. Bunnett   +3 more
core   +1 more source

Plasma met-enkephalin, beta-endorphin and leu-enkephalin levels in human hepatic encephalopathy

open access: yes, 2007
257-265To address the role of the opioid system in the pathogenesis of hepatic encephalopathy [HE] we measured plasma met- enkephalin, beta -endorphin and leu- enkephalin in patients with different grades of HE compared to control subjects and patients ...
El Khayat, H.   +4 more
core  

Delivery of Neuropeptides from the Periphery to the Brain: Studies with Enkephalin

open access: yes, 2016
Many peptides with the potential of therapeutic action for brain disorders are not in clinical use because they are unable to cross the blood−brain barrier (BBB) following peripheral administration.
Yoram Shechter (2298067)   +5 more
core   +1 more source

Synthesis and opioid activities of stereoisomers and other D-amino acid analogs of methionine-enkephalin

open access: yes, 1976
A series of D-amino acid-substituted analogs of the opiate peptide, methionine 5-enkephalin, were synthesized by solid-phase methods and tested for their abilities to inhibit electrically-evoked contractions of mouse vasa deferentia and to compete with ...
Fertel, R   +9 more
core   +1 more source

Enkephalin reduces calcium action potentials in Rohon-Beard neurons in vivo

open access: yes, 1983
Rohon-Beard neurons of the Xenopus spinal cord develop somatic Ca++- dependent action potentials at early embryonic stages. Because many Ca++-dependent events are blocked or reduced by enkephalin in other neuronal systems, we tested the effect of met ...
JL Bixby   +3 more
core   +1 more source

Co‐Expression of Tardive Dyskinesia and Drug‐Induced Parkinsonism in Rats Chronically Treated With Haloperidol

open access: yesNeuropsychopharmacology Reports
Aim We aimed to create a rat model of drug‐induced parkinsonism and tardive dyskinesia by chronic administration of haloperidol and examine the expression of direct and indirect pathway markers in the striatum of the model rats.
Iku Kinoshita   +7 more
doaj   +1 more source

CIRCULATING CATECHOLAMINES, MELATONIN AND ENKEPHALIN IN MAN FOLLOWING ADMINISTRATION OF A MET-ENKEPHALIN ANALOG

open access: yes, 2016
The met-enkephalin analogue, D-Ala2-MePhe4-met-enkephalin-(C)-ol (DAMME), was given i.v. to 6 normal subjects. Elevations in plasma prolactin and growth hormone (GH) occurred in association with significant falls in plasma epinephrine and norepinephrine.

core  

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