Results 41 to 50 of about 33,668 (227)

Delta Opioid Receptor Signaling Promotes Resilience to Stress Under the Repeated Social Defeat Paradigm in Mice

Frontiers in Molecular Neuroscience, 2018
The adaptation to chronic stress is highly variable across individuals. Resilience to stress is a complex process recruiting various brain regions and neurotransmitter systems. The aim of this study was to investigate the involvement of endogenous opioid
Mathilde S. Henry, Kanchan Bisht, Nathalie Vernoux, Louis Gendron, Louis Gendron, Louis Gendron, Angélica Torres-Berrio, Guy Drolet, Guy Drolet, Marie-Ève Tremblay, Marie-Ève Tremblay   +10 more
doaj   +1 more source

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model-0 [PDF]

, 2011
to induce pancreatitis were given pancreatic injection of vehicle (DMEM) only. . Some animals with alcohol and high-fat diet induced pancreatitis were given pancreatic HSV-β-gal applications, serving as the vector control.
Yong Ren (86476), Hong Yang (37298), David C Yeomans (37009), Terry A McNearney (86474), Karin N Westlund (86477), Ying Lu (66401), Steven P Wilson (66410), Rong Chu (86475)   +7 more
core   +1 more source

Alterations in Cortical and Basal Ganglia Levels of Opioid Receptor Binding in a Rat Model of l-DOPA-Induced Dyskinesia

Neurobiology of Disease, 2001
Opioid receptor-binding autoradiography was used as a way to map sites of altered opioid transmission in a rat model of l-DOPA-induced dyskinesia. Rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathways sustained a 3-week treatment ...
P.A. Johansson, M. Andersson, K.E. Andersson, M.A. Cenci   +3 more
doaj   +1 more source

Cocaine Reduces the Neuronal Population While Upregulating Dopamine D2-Receptor-Expressing Neurons in Brain Reward Regions: Sex-Effects

Frontiers in Pharmacology, 2021
Addiction to cocaine is associated with dysfunction of the dopamine mesocortical system including impaired dopamine-2 receptor (D2r) signaling. However, the effects of chronic cocaine on neuronal adaptations in this system have not been systematically ...
Kevin Clare, Chelsea Pan, Gloria Kim, Kicheon Park, Juan Zhao, Nora D. Volkow, Zhicheng Lin, Congwu Du   +7 more
doaj   +1 more source

Enkephalin in bovine adrenal gland: Multiple molecular forms of [met5]-enkephalin immunoreactive peptides [PDF]

, 1980
The existence and heterogeneity of enkephalin-like substances in bovine adrenal glands has been demonstrated using enkephalin radioimmunoassays. Both [met5]- and [leu5]-enkephalins were found to be highly enriched in the medulla i.e.
E. Costa, A. M. Di Giulio, W. Fratta, H. Yang, J. Hong, E. A. Majane   +5 more
core   +1 more source

Striatal Neuropeptides Enhance Selection and Rejection of Sequential Actions

Frontiers in Computational Neuroscience, 2017
The striatum is the primary input nucleus for the basal ganglia, and receives glutamatergic afferents from the cortex. Under the hypothesis that basal ganglia perform action selection, these cortical afferents encode potential “action requests.” Previous
David Buxton, Enrico Bracci, Paul G. Overton, Kevin Gurney   +3 more
doaj   +1 more source

Avian opioid peptides: evolutionary considerations, functional roles and a challenge to address critical questions

Frontiers in Physiology, 2023
The present review considers the putative hormonal opioid peptides in birds. In birds and all other vertebrates, there are four opioid related genes encoding a series of peptides.
Krystyna Pierzchała-Koziec, Colin G. Scanes   +1 more
doaj   +1 more source

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model-10 [PDF]

, 2011
To induce pancreatitis were given pancreatic injection of vehicle (DMEM) only. . Some animals with alcohol and high-fat diet induced pancreatitis were given pancreatic HSV-β-gal applications, serving as the vector control.
Yong Ren (86476), Hong Yang (37298), David C Yeomans (37009), Terry A McNearney (86474), Karin N Westlund (86477), Ying Lu (66401), Steven P Wilson (66410), Rong Chu (86475)   +7 more
core   +1 more source

The role of BDNF/TrkB signaling in acute amphetamine-induced locomotor activity and opioid peptide gene expression in the rat dorsal striatum

Frontiers in Systems Neuroscience, 2011
Exposure to psychostimulants increases brain-derived neurotrophic factor (BDNF) mRNA and protein levels in the cerebral cortex and subcortical structures.
Jacqueline F McGinty, Alexandra J Bache, Nortorious T Coleman, Wei-Lun eSun   +3 more
doaj   +1 more source

Involvement of the Opioid Peptide Family in Cancer Progression

Biomedicines, 2023
Peptides mediate cancer progression favoring the mitogenesis, migration, and invasion of tumor cells, promoting metastasis and anti-apoptotic mechanisms, and facilitating angiogenesis/lymphangiogenesis.
Manuel Lisardo Sánchez, Francisco D. Rodríguez, Rafael Coveñas   +2 more
doaj   +1 more source