Results 51 to 60 of about 47,172 (213)
Opioid Receptors in Immune and Glial Cells-Implications for Pain Control [PDF]
Opioid receptors comprise μ (MOP), δ (DOP), κ (KOP), and nociceptin/orphanin FQ (NOP) receptors. Opioids are agonists of MOP, DOP, and KOP receptors, whereas nociceptin/orphanin FQ (N/OFQ) is an agonist of NOP receptors.
Celik, Melih Ö., Machelska, Halina
core +1 more source
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
wiley +1 more source
: The effects of the administration of the opioid agonist, morphine, on plasma and tissue concentrations of Met-enkephalin were determined in 14 wk old female chickens.
Colin G. Scanes +1 more
doaj +1 more source
The noradrenergic nucleus locus coeruleus is a key component of the stress circuitry of the brain. During stress, the neuropeptide corticotropin-releasing factor (CRF) is secreted onto LC, increasing LC output and norepinephrine concentration in the ...
John A. Tkaczynski +2 more
doaj +1 more source
Effective Sampling in the Configurational Space by the Multicanonical-Multioverlap Algorithm
We propose a new generalized-ensemble algorithm, which we refer to as the multicanonical-multioverlap algorithm. By utilizing a non-Boltzmann weight factor, this method realizes a random walk in the multi-dimensional, energy-overlap space and explores ...
B. A. Berg +5 more
core +1 more source
The competitive interplay of 12‐oxophytodienoic acid (OPDA), protein thiols, and glutathione
12‐Oxophytodienoic acid (OPDA) is a phytohormone involved in plant growth and stress defense. Due to its cyclopentenone moiety, OPDA can form Michael adducts with thiol‐containing compounds such as glutathione and cysteine residues of proteins, resulting in alterations of the cellular redox regulatory network.
Madita Knieper +8 more
wiley +1 more source
Objective. The aim of the present study was to demonstrate the spatial relationship between the c-Fos immunoreactive cells elicited by an acute treatment with neuroleptics including amisulpride (AMI), olanzapine (OLA), quetiapine (QUE), and aripiprazole (
Kiss Alexander, Osacka Jana
doaj +1 more source
Neuropeptides, a diverse class of signaling molecules in the nervous system, modulate various biological effects including membrane excitability, synaptic transmission and synaptogenesis, gene expression, and glial cell architecture and function. To date,
Sanne M. Casello +9 more
doaj +1 more source
5-HT6R Viral Vector-Mediated Indirect Pathway Activation in the Dorsolateral Striatum: A Discussion on Basal Ganglia Habitual and Goal-Directed Circuits [PDF]
Altering maladaptive behavioral tendencies is relevant for clinical interventions, making research on underlying mechanisms of habit essential. Mechanisms of habit are explored here with differential activation of the indirect pathway in the basal ...
Winn, Caleb S
core +1 more source
Structure of the Energy Landscape of Short Peptides
We have simulated, as a showcase, the pentapeptide Met-enkephalin (Tyr-Gly-Gly-Phe-Met) to visualize the energy landscape and investigate the conformational coverage by the multicanonical method.
Berg B. A. +5 more
core +1 more source

