Results 181 to 190 of about 35,580 (228)
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Acetylcholinesterase converts Met5-enkephalin-containing peptides to Met5-enkephalin
Neuroscience Letters, 1988Acetylcholinesterase (AChE; E.C. 3.1.1.7) was incubated with a number of enkephalin-containing neuropeptides found in the bovine adrenal medulla. Met5-enkephalin and Leu5-enkephalin were the most stable of the peptides studied, while precursors of Met5-enkephalin were converted to Met5-enkephalin. AChE is therefore capable of limited peptidase activity
M, Dowton, M, Boelen
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Life Sciences, 1983
Studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin A from adrenal medulla and human pheochromocytoma have revealed that this precursor contains 4 copies of methionine-enkephalin(Met-Enk) and one copy each of leu-enkephalin (Leu-Enk), methionine-enkephalin-Arg6-Gly7-Leu8(Met-Enk-Arg6-Gly7-Leu8) and methionine ...
M, Sakamoto +6 more
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Studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin A from adrenal medulla and human pheochromocytoma have revealed that this precursor contains 4 copies of methionine-enkephalin(Met-Enk) and one copy each of leu-enkephalin (Leu-Enk), methionine-enkephalin-Arg6-Gly7-Leu8(Met-Enk-Arg6-Gly7-Leu8) and methionine ...
M, Sakamoto +6 more
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2000
Enkephalin analogs for multivalent ligand systems, bivalent enkephalins, multivalent enkephalins on polymers, multivalent ligands on vesicles, simultaneous activation of two different receptor systems, and cell interactions of enkephalin/polypeptide conjugates are described.
S, Kimura, Y, Imanishi
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Enkephalin analogs for multivalent ligand systems, bivalent enkephalins, multivalent enkephalins on polymers, multivalent ligands on vesicles, simultaneous activation of two different receptor systems, and cell interactions of enkephalin/polypeptide conjugates are described.
S, Kimura, Y, Imanishi
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International Journal of Peptide and Protein Research, 1982
The Gly3residue in Gly2‐ and D‐Ala2‐enkephalins has been replaced by ΔAla3and Ser3in order to examine the effect on binding to the Δ and μ opiate receptors. [D‐Ala2, ΔAla3, Leu5]‐enkephalin maintains most of its receptor binding affinities for both sites.
Yasuyuki Shimohigashi +1 more
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The Gly3residue in Gly2‐ and D‐Ala2‐enkephalins has been replaced by ΔAla3and Ser3in order to examine the effect on binding to the Δ and μ opiate receptors. [D‐Ala2, ΔAla3, Leu5]‐enkephalin maintains most of its receptor binding affinities for both sites.
Yasuyuki Shimohigashi +1 more
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Enkephalins: immunomodulators.
Federation proceedings, 1985Our original studies of the enkephalins were centered on behavioral stress and brain dopaminergic interactions. More recently we discovered the enkephalins to be immunomodulators as evidenced by their enhancement effects on lymphocyte blastogenesis in mice, increases in the sizes of the thymus or spleen in rodents, and prolongation of survival of BDF1 ...
N P, Plotnikoff +4 more
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Polish journal of pharmacology and pharmacy, 1983
Basing on the conclusions drawn from the biological activities of previously synthesized enkephalin analogues, a new class of enkephalin analogues named double-enkephalins have been proposed, in which C-terminal amino acid residue is replaced by a second active fragment of enkephalin analogue connected by diamine bridge.
A W, Lipkowski +2 more
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Basing on the conclusions drawn from the biological activities of previously synthesized enkephalin analogues, a new class of enkephalin analogues named double-enkephalins have been proposed, in which C-terminal amino acid residue is replaced by a second active fragment of enkephalin analogue connected by diamine bridge.
A W, Lipkowski +2 more
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Dehydro-enkephalins. VIII. Attempted synthesis of dehydrotyrosine-enkephalins.
International journal of peptide and protein research, 1983Two kinds of dehydropeptide analogs of enkephalin containing a delta Tyr unit at the N-terminus have been synthesized by coupling Boc-delta Tyr-(Cl2 Bzl)-OH with amino acid amides and tetrapeptide esters using the water soluble carbodiimide-HOBt method. Pentapeptides consisting of delta Tyr1, and delta Phe4 or delta Leu5 were also prepared. Ultraviolet
Y, Shimohigashi +3 more
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