Results 11 to 20 of about 37,089 (225)
Regional and Compartmental Changes Drive Progressive Patterns of Striatal Degeneration in X-Linked Dystonia Parkinsonism. [PDF]
Ann NeurolObjective Initially described in 1976, X‐linked dystonia parkinsonism (XDP) is a neurodegenerative disease that can be characterized by the presentation of dystonia and parkinsonism symptoms. Although this disease bears some resemblance to other neurodegenerative diseases in terms of symptomatology, the pathological signature of XDP is still unclear ...
Tan AYS +19 more
europepmc +2 more sources
Endogenous Opioids in Crohn’s Disease
Biomedicines, 2023 Caring for patients with Crohn’s disease (CD) is a serious challenge in modern medicine. The increasing incidence of CD among adolescents and the severe course of the disease create the need for new methods of diagnosis and therapy.
Adrian Martyniak +2 more
doaj +1 more source
Increased Serum Met-enkephalin Level in Patients with Intrahepatic Cholestasis of Pregnancy
Bagcilar Medical Bulletin, 2022 Objective:To evaluate met-enkephalin levels in women with intrahepatic cholestasis of pregnancy (ICP) by comparison to healthy controls and to compare the pregnancy outcomes.Method:This cross-sectional study was conducted in 43 pregnant women with ICP ...
Sema Süzen Çaypınar, Murat Ekin
doaj +1 more source
Viruses, 2021 Psychostimulant use is a major comorbidity in people living with HIV, which was initially explained by them adopting risky behaviors that facilitate HIV transmission.
María Amparo Assis +2 more
doaj +1 more source
Actions of D-Ala2-D-Leu5-enkephalin and dynorphin A (1–17) on neocortical neurons in vitro [PDF]
, 1984 Intracellular recordings were made from neocortical neurons in vitro. Application of D-Ala2-D-Leu5-enkephalin (DADL) by different methods produced a decrease in EPSP amplitude and in the amplitude of L-glutamate-induced depolarizations without changes in
Zieglgänsberger, Walter, Sutor, Bernd
core +1 more source
Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-laboring myometrium [PDF]
, 2013 The existence of opioid receptors in mammalian myometrial tissue is now widely accepted. Previously enkephalin degrading enzymes have been shown to be elevated in pregnant rat uterus and a met-enkephalin analogue has been shown to alter spontaneous ...
McMorrow, Jason P. +10 more
core +1 more source
Frontiers in Molecular Neuroscience, 2018 Epilepsies are a group of common neurological diseases exerting a strong burden on patients and society, often lacking clear etiology and effective therapeutical strategies.
Johannes Burtscher +10 more
doaj +1 more source
Journal of Pharmacological Sciences, 2007 Previous in vitro studies have shown that the degradation of [Met5]enkephalin-Arg6-Phe7 during incubation with cerebral membrane preparations is largely prevented by a mixture of three peptidase inhibitors: amastatin, captopril, and phosphoramidon.
Shigeru Takahashi +5 more
doaj +1 more source
Biomedicine & Pharmacotherapy, 1997 Recent data support the view that neuropeptide mediators, in particular opioid peptides, participate in the control of hematopoiesis. The main arguments are: neuropeptides modulate the functions of lymphoid cells, macrophages and mature granulocytes; they control cell proliferation and differentiation in many tissues, particularly during embryogenesis;
Gabrilovac, Jelka +4 more
openaire +4 more sources
Annals of Hepatology, 2008 Endogenous opioids participate in growth regulation. Liver regeneration relates to growth. Thus, we explored the expression of methionine enkephalin and of the delta opioid receptor 1 immunoreactivities with a polyclonal rabbit antibody in deparaffinized
Vijaya D. Boyella +2 more
doaj +1 more source