Results 191 to 200 of about 46,429 (222)

Immunohistochemical localization of Met-enkephalin, Met-enkephalin-Arg6-Gly7-Leu8, Met-enkephalin-Arg6-Phe7 and Leu-enkephalin in human adrenal medulla and pheochromocytomas

Peptides, 1984
Immunohistochemical localization of Met-enkephalin, Met-enkephalin-Arg6-Gly7-Leu8, Met-enkephalin-Arg6-Phe7 and Leu-enkephalin was studied in human adrenal medulla and pheochromocytomas at the light and electron microscopic levels. Both adrenal medulla and pheochromocytomas (4 adrenal, 1 extra-adrenal) showed scattered or clustered cells which ...
Keiichi Watanabe, Takaaki Yoshimasa, R. Yoshiyuki Osamura, Hiroo Imura, Kazuwa Nakao   +4 more
openaire   +3 more sources

Cerebral application of enkephalins

Experientia, 1977
Implantation of enkephalins A or B into the ventral thalamus or injection into the lateral ventricle of rats evoked only weak signs of stereotyped behavior, but did not cause gnawing.
Felix Bergmann, Felix Bergmann, D Roth, D Roth, R Altstetter, R Altstetter, M Wilchek, M Wilchek, M Oreg, M Oreg, M. Chaimovitz, M. Chaimovitz, C Hexter, C Hexter, V. Pasternak, V. Pasternak   +15 more
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Parallel distribution of methionine-enkephalin-arg6-gly7-leu8 with methionine-enkephalin, leucine-enkephalin and methionine-enkephalin-arg6-phe7 in human and bovine brains

Life Sciences, 1983
Using specific radioimmunoassays(RIAs) for methionine-enkephalin(Met-Enk), leucine-enkephalin(Leu-Enk), methionine-enkephalin-Arg6-Gly7-Leu8 (Met-Enk-Arg-Gly-Leu) and methionine-enkephalin-Arg6-Phe7 (Met-Enk-Arg-Phe), we studied the regional distribution of these opioid peptides in human and bovine brains.
Takaaki Yoshimasa, Noboru Yanaihara, Yoshio Ikeda, Makoto Sakamoto, Hiroo Imura, Mitsuaki Suda, Kazuwa Nakao   +6 more
openaire   +3 more sources

Demonstration and characterization of immunoreactive methionine-enkephalin, leucine-enkephalin, methionine-enkephalin-Arg6-Gly7-Leu8 and methionine-enkephalin-Arg6-Phe7 in human phaeochromocytoma

Acta Endocrinologica, 1984
Abstract. To elucidate whether or not human phaeochromocytoma contains methionine-enkephalin-Arg6-Gly7-Leu8 (Met-enkephalin-Arg-Gly-Leu) and methionine-enkephalin-Arg6-Phe7 (Met-enkephalin-Arg-Phe) together with methionine-enkephalin (Met-enkephalin) and leucine-enkephalin (Leu-enkephalin), all of which are known to exist in the same precursor molecule
Shinichiro Shimbo, Takashi Ishihara, Satoshi Hamada, Yoshio Ikeda, Hiroo Imura, Shigeru Matsukura, Kazuwa Nakao, Mitsuaki Suda, Masataka Manno, Narito Morii, Teruya Yoshimi, Takaaki Youshimasa, Makoto Sakamoto, Toru Mori   +13 more
openaire   +3 more sources

Met-enkephalin-arg6-gly7-leu8 exists together with met-enkephalin-arg6-phe7, met-enkephalin and leu-enkephalin in human stomach

Life Sciences, 1983
Studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin A from adrenal medulla and human pheochromocytoma have revealed that this precursor contains 4 copies of methionine-enkephalin(Met-Enk) and one copy each of leu-enkephalin (Leu-Enk), methionine-enkephalin-Arg6-Gly7-Leu8(Met-Enk-Arg6-Gly7-Leu8) and methionine ...
Noboru Yanaihara, Mitsuaki Suda, Hiroo Imura, Takaaki Yoshimasa, Kazumasa Nakao, Makoto Sakamoto, Yasutaka Ikeda   +6 more
openaire   +3 more sources

Plasma Met-Enkephalin and Leu-Enkephalin in Chronic Renal Failure

Nephrology Dialysis Transplantation, 1987
Plasma met-enkephalin and leu-enkephalin has been measured in a group of 28 patients with chronic renal failure, to discover whether these opioids are affected by standard haemodialysis and haemofiltration. Met-enkephalin was markedly higher (P less than 0.001) in uraemic patients than in a group of 13 normal subjects, and was directly related to ...
Carmine Zoccali, Francesca Mallamaci, M. Ciccarelli, M. Lotti, Quirino Maggiore, G. C. Zucchelli   +5 more
openaire   +3 more sources

Acetylcholinesterase converts Met5-enkephalin-containing peptides to Met5-enkephalin

Neuroscience Letters, 1988
Acetylcholinesterase (AChE; E.C. 3.1.1.7) was incubated with a number of enkephalin-containing neuropeptides found in the bovine adrenal medulla. Met5-enkephalin and Leu5-enkephalin were the most stable of the peptides studied, while precursors of Met5-enkephalin were converted to Met5-enkephalin. AChE is therefore capable of limited peptidase activity
Meeuwis K. Boelen, Mark Dowton
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Immunofluorescence with Met-enkephalin and Leu-enkephalin antibodies in the guinea pig cochlea

Hearing Research, 1984
We have applied an indirect immunofluorescence technique to cryostat sections of guinea pig cochleas using Met-enkephalin and Leu-enkephalin antisera. With both antisera, high immunofluorescence was seen in the inner spiral bundle, the tunnel spiral bundle and the intraganglionic spiral bundle. Immunoreactivity persisted to a dilution of 1/50 000.
Rémy Pujol, Michel Eybalin
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Methionine Enkephalin, But not Leucine Enkephalin, is Excreted in Bile [PDF]

Clinical Science, 1988
M S Losowsky, Judith Thornton
openaire   +1 more source

Enkephalin and Drug Dependence*

British Journal of Addiction to Alcohol & Other Drugs, 1976
SummaryThe author traces the development of the concept that led to the discovery of endogenous ligands for the morphine receptor – the Enkephalins. The pharmacological properties and possible physiological function of these ligands is discussed and a possible explanation of morphine dependence is presented.
openaire   +3 more sources