Results 31 to 40 of about 18,028 (272)

The organisation of spinoparabrachial neurons in the mouse [PDF]

open access: yes, 2015
The anterolateral tract (ALT), which originates from neurons in lamina I and the deep dorsal horn, represents a major ascending output through which nociceptive information is transmitted to brain areas involved in pain perception.
Cameron, Darren   +5 more
core   +1 more source

Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics

open access: yesFrontiers in Cellular Neuroscience, 2015
The endogenous opioid peptides dynorphins and enkephalins may be involved in brain-area specific synaptic adaptations relevant for different stages of an addiction cycle.
Daniil eSarkisyan   +11 more
doaj   +1 more source

Synthesis method of asymmetric gold particles. [PDF]

open access: yes, 2017
Asymmetric particles can exhibit unique properties. However, reported synthesis methods for asymmetric particles hinder their application because these methods have a limited scale and lack the ability to afford particles of varied shapes.
Hahm, Eunil   +3 more
core   +1 more source

Racecadotril for acute diarrhoea in children: systematic review and meta-analyses [PDF]

open access: yes, 2015
OBJECTIVE Racecadotril is an antisecretory agent that can prevent fluid/electrolyte depletion from the bowel as a result of acute diarrhoea, without affecting intestinal motility. An up-to-date systematic review is indicated to summarise the evidence on
Alam   +31 more
core   +1 more source

From morphine to endogenous opioid peptides, e.g., endorphins: the endless quest for the perfect painkiller

open access: yesSubstantia, 2018
Opium was known since the Neolithic era and in 5th century wild Papaver use was reported to induce sleep and relieving pain. First active component isolated from Opium was morphine, the paradigm of a natural product discovered 150 years before isolation ...
Anna Maria Papini
doaj   +1 more source

Crosslinking of membrane CD13 in human neutrophils mediates phagocytosis and production of reactive oxygen species, neutrophil extracellular traps and proinflammatory cytokines

open access: yesFrontiers in Immunology, 2022
Aminopeptidase N, or CD13, is a cell membrane ectopeptidase highly expressed in myeloid cells. Through its enzymatic activity, CD13 regulates the activity of several bioactive peptides, such as endorphins and enkephalins, chemotactic peptides like MCP-1 ...
Erandi Pérez-Figueroa   +2 more
doaj   +1 more source

Neuronal pathways in tendon healing and tendinopathy : update [PDF]

open access: yes, 2016
The regulatory mechanisms involved in tendon homeostasis and repair are not fully understood. Accumulating data, however, demonstrate that the nervous system, in addition to afferent (sensory) functions, through efferent neuronal pathways plays an active
Ackermann, Paul   +5 more
core   +1 more source

Acetaldehyde‐enkephalins: pronounced changes in the opiate activity of methionine‐enkephalin and leucine‐enkephalin on reaction with acetaldehyde [PDF]

open access: yesFEBS Letters, 1980
We have shown that the two major endogenous opioid peptides, methionine-enkephalin and leucineenkephalin [ 1,2] (enkephalin [Met’] and enkephalin[Leu’]) rapidly react with acetaldehyde in aqueous buffers to give a stable ‘acetaldehyde-enkephalin’ adduct, referred to as ‘acetaldehyde-enkephalin[Met’]’ and ‘acetaldehyde-enkephalin [Leu’]‘, respectively ...
Summers, Michael C., Hayes, Roger J.
openaire   +2 more sources

The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential

open access: yesFrontiers in Molecular Neuroscience, 2017
Temporal lobe epilepsy is considered to be one of the most common and severe forms of focal epilepsies. Patients often develop cognitive deficits and emotional blunting along the progression of the disease.
Johannes Burtscher, Christoph Schwarzer
doaj   +1 more source

Neuropharmacological targets for drug action in vestibular sensory pathways [PDF]

open access: yes, 2017
The use of pharmacological agents is often the preferred approach to the management of vestibular dysfunction. In the vestibular sensory pathways, the sensory neuroepithelia are thought to be influenced by a diverse number of neuroactive substances that ...
Jones, Timothy A, Lee, Choongheon
core   +3 more sources

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