Results 31 to 40 of about 34,698 (281)
Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.
Proceedings of the National Academy of Sciences of the United States of America, 1983 The conformationally restricted, cyclic, disulfide-containing, enkephalin analogs [2-D-penicillamine, 5-L-penicillamine]enkephalin [(D-Pen2,L-Pen5]enkephalin) and [2-D-penicillamine, 5-D-penicillamine]enkephalin [(D-Pen2,D-Pen5]enkephalin) were ...
H. Mosberg +6 more
semanticscholar +1 more source
Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics
Frontiers in Cellular Neuroscience, 2015 The endogenous opioid peptides dynorphins and enkephalins may be involved in brain-area specific synaptic adaptations relevant for different stages of an addiction cycle.
Daniil eSarkisyan +11 more
doaj +1 more source
Neuropharmacological targets for drug action in vestibular sensory pathways [PDF]
, 2017 The use of pharmacological agents is often the preferred approach to the management of vestibular dysfunction. In the vestibular sensory pathways, the sensory neuroepithelia are thought to be influenced by a diverse number of neuroactive substances that ...
Jones, Timothy A, Lee, Choongheon
core +3 more sources
Racecadotril for acute diarrhoea in children: systematic review and meta-analyses [PDF]
, 2015 OBJECTIVE Racecadotril is an antisecretory agent that can prevent fluid/electrolyte depletion from the bowel as a result of acute diarrhoea, without affecting intestinal motility. An up-to-date systematic review is indicated to summarise the evidence on
Alam +31 more
core +1 more source
THE DISTRIBUTION OF METHIONINE‐ENKEPHALIN AND LEUCINE‐ENKEPHALIN IN THE BRAIN AND PERIPHERAL TISSUES [PDF]
British Journal of Pharmacology, 1977 A method is described for the rapid extraction of opioid peptides from the brain and other tissues. The method is based on acid extraction of tissues followed by adsorption of the extract onto Amberlite XAD‐2 resin. Elution with methanol separates the enkephalins and α‐endorphin from β‐endorphin.Over 90% of the opioid peptide activity isolated from ...
Jeffery Hughes +2 more
openaire +5 more sources
Frontiers in Immunology, 2022 Aminopeptidase N, or CD13, is a cell membrane ectopeptidase highly expressed in myeloid cells. Through its enzymatic activity, CD13 regulates the activity of several bioactive peptides, such as endorphins and enkephalins, chemotactic peptides like MCP-1 ...
Erandi Pérez-Figueroa +2 more
doaj +1 more source
The effect of hand H7 acupressure on the non-reactive pattern of fetal non stress test: A randomized clinical trial [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2022 Introduction: Non-stress test is the most widely used primary method for assessing fetal health. The mother's mental state affects the fetal heart rate pattern.
Nahid Barati +5 more
doaj +1 more source
Biochemical Journal, 1984 Endopeptidase-24.11 (EC 3.4.24.11), purified to homogeneity from pig kidney, was shown to hydrolyse a wide range of neuropeptides, including enkephalins, tachykinins, bradykinin, neurotensin, luliberin and cholecystokinin.
R. Matsas, A. Kenny, A. Turner
semanticscholar +1 more source
Three-dimensional structure of monoanionic methionine-enkephalin: X-ray structure of tert-butyloxycarbonyl-Tyr-Gly-Gly-(4-bromo)Phe-Met-OH [PDF]
, 1984 The conformation of tert-butyloxycarbonyl-Tyr-Gly-Gly-(4-bromo)Phe-Met-OH, as a monoanionic derivative of Met-enkephalin, was elucidated by X-ray crystal analysis. The molecule took an extended conformation which was bended at the Phe residue.
Doi, Mitsunobu +6 more
core +1 more source
Substantia, 2018 Opium was known since the Neolithic era and in 5th century wild Papaver use was reported to induce sleep and relieving pain. First active component isolated from Opium was morphine, the paradigm of a natural product discovered 150 years before isolation ...
Anna Maria Papini
doaj +1 more source