Distinct forms of synaptic inhibition and neuromodulation regulate calretinin positive neuron excitability in the spinal cord dorsal horn [PDF]
, 2016 The dorsal horn (DH) of the spinal cord contains a heterogenous population of neurons that process incoming sensory signals before information ascends to the brain.
Boyle, K.A. +6 more
core +1 more source
Acetaldehyde‐enkephalins: pronounced changes in the opiate activity of methionine‐enkephalin and leucine‐enkephalin on reaction with acetaldehyde [PDF]
FEBS Letters, 1980 We have shown that the two major endogenous opioid peptides, methionine-enkephalin and leucineenkephalin [ 1,2] (enkephalin [Met’] and enkephalin[Leu’]) rapidly react with acetaldehyde in aqueous buffers to give a stable ‘acetaldehyde-enkephalin’ adduct, referred to as ‘acetaldehyde-enkephalin[Met’]’ and ‘acetaldehyde-enkephalin [Leu’]‘, respectively ...
Roger J. Hayes, Michael C. Summers
openaire +3 more sources
Neuropeptidases, Stress, and Memory—A Promising Perspective
AIMS Neuroscience, 2016 Stress has been demonstrated to be a key modulator in learning and memory processes, in which the hippocampus plays a central role. A great number of neuropeptides have been reported to modulate learning and memory under stressful conditions ...
I. Prieto +3 more
doaj +1 more source
Proenkephalin A 119-159 (Penkid) Is an Early Biomarker of Septic Acute Kidney Injury: The Kidney in Sepsis and Septic Shock (Kid-SSS) Study [PDF]
, 2018 Introduction: Sepsis is the leading cause of acute kidney injury (AKI) in critically ill patients. The Kidney in Sepsis and Septic Shock (Kid-SSS) study evaluated the value of proenkephalin A 119-159 (penkid)—a sensitive biomarker of glomerular function,
Antonelli, M. +25 more
core +2 more sources
Endogenous analgesia mediated by CD4+ T lymphocytes is dependent on enkephalins in mice
Journal of Neuroinflammation, 2016 BackgroundT cell-derived opioids play a key role in the control of inflammatory pain. However, the nature of opioids produced by T cells is still matter of debate in mice.
L. Basso +7 more
semanticscholar +1 more source
A MATERIAL FULL OF PROMISES:Hg1−XCdXTe - MERCURY CADMIUM TELLURID
Journal of Engineering Science (Chişinău), 2023 In recent decades’ doctors and scientists have intensively researched the effect of infrared applications. The rays of infrared devices penetrate the body to a depth of about 5 cm and provide a pleasant warmth, stimulating blood circulation and
BĂJENESCU, Titu-Marius I.
doaj +1 more source
Endocrine Regulations, 2019 Objective. Enkephalins are neuropeptides involved in functions such as pain modulation and/ or cognitive processes. It has been reported that dietary fat modifies enkephalins in the brain.
Segarra Ana B. +8 more
doaj +1 more source
Protein Folding Simulations in a Deformed Energy Landscape [PDF]
Eur. Phys. J. B 12 (1999) 607-612, 2000 A modified version of stochastic tunneling, a recently introduced global optimization technique, is introduced as a new generalized-ensemble technique and tested for a benchmark peptide, Met-enkephalin.
arxiv +1 more source
Involvement of the Opioid Peptide Family in Cancer Progression
Biomedicines, 2023 Peptides mediate cancer progression favoring the mitogenesis, migration, and invasion of tumor cells, promoting metastasis and anti-apoptotic mechanisms, and facilitating angiogenesis/lymphangiogenesis.
Manuel Lisardo Sánchez +2 more
doaj +1 more source
Metropolis simulations of Met-Enkephalin with solvent-accessible area parameterizations [PDF]
Phys. Rev. E 69, 026703 (2004), 2003 We investigate the solvent-accessible area method by means of Metropolis simulations of the brain peptide Met-Enkephalin at 300$ K$. For the energy function ECEPP/2 nine atomic solvation parameter (ASP) sets are studied. The simulations are compared with one another, with simulations with a distance dependent electrostatic permittivity $\epsilon (r ...
arxiv +1 more source