Results 41 to 50 of about 12,744 (238)
Anesthetic Mechanism of Myeloacupuncture in Joints аnd Spine Pathology
Bolʹ, Sustavy, Pozvonočnik, 2015 The article presents a literature review on the application of such method of reflexotherapy acupuncture as myeloacupuncture used in the pathology of the peripheral joints and spine.
V.V. Yakovlenko +2 more
doaj +1 more source
A drug delivery strategy: binding enkephalin to asialoglycoprotein receptor by enzymatic galactosylation. [PDF]
PLoS ONE, 2014 Glycosylation of biopharmaceuticals can mediate cell specific delivery by targeting carbohydrate receptors. Additionally, glycosylation can improve the physico-chemical (drug-like) properties of peptide based drug candidates.
Michelle P Christie +8 more
doaj +1 more source
Chemistry &Biodiversity, EarlyView.Endophytic fungi of P. auritum were evaluated for their ability to produce inhibitors of formation of advanced glycation end products (AGEs). Neopestalotiopsis sp. H2 and Diaporthe sp. H5 extracts were the most active. So, we performed their chemical profiling by untargeted and phenolics‐targeted metabolomic approaches to identify the potential ...
Lory Sthephany Rochín‐Hernández +3 more
wiley +1 more source
Wellcome Open Research, 2018 Background: Functional deletion of the Scn9a (sodium voltage-gated channel alpha subunit 9) gene encoding sodium channel Nav1.7 makes humans and mice pain-free. Opioid signalling contributes to this analgesic state.
Vanessa Pereira +5 more
doaj +1 more source
Chemistry &Biodiversity, EarlyView.ABSTRACT Maize is an important crop worldwide with approximately 1200 million tons consumed and a market size worth $143 billion. Environmental stress influence production of crops and mitigating these ensures optimum production. Dicarboxylic acids are known as emulsifying agents that mitigate various stresses in plants.
Mhlonipheni Msomi +3 more
wiley +1 more source
Marine Drugs, 2022 Antimicrobial peptides (AMPs) are found widespread in nature and possess antimicrobial and immunomodulatory activities. Due to their multifunctional properties, these peptides are a focus of growing body of interest and have been characterized in several
Giacomo Zaccone +15 more
doaj +1 more source
Macromolecular Rapid Communications, EarlyView.Lyotropic Ion‐Specific Effects Drive the Synthesis of Ultra‐Small Protein Nanoparticles via Electrohydrodynamic Jetting. ABSTRACT Protein‐based nanoparticles offer tailored bioactivity and biodegradability that are distinct from their synthetic polymeric counterparts.
Muhammad Haseeb Iqbal +4 more
wiley +1 more source
Enkephalins: Endogenous Analgesics with an Emerging Role in Stress Resilience
Neural Plasticity, 2017 Psychological stress is a state of mental or emotional strain or tension that results from adverse or demanding circumstances. Chronic stress is well known to induce anxiety disorders and major depression; it is also considered a risk factor for ...
Mathilde S. Henry +3 more
doaj +1 more source
Neurobiology of Disease, 2020 Neuropeptides are important signalling molecules in the brain and alterations in their expression levels have been linked to neurological disorders such as Parkinson's disease. It is challenging to map neuropeptide changes across and within brain regions
Heather Hulme +10 more
doaj +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley +1 more source