Results 71 to 80 of about 33,942 (331)
, 1980 1 The activity pattern of analogues of the enkephalins was determined in four parallel assays, the inhibition of the electrically evoked contraction of the guinea‐pig ileum and mouse vas deferens at 36°C and the inhibition of [3H]‐naltrexone and [3H ...
H. Kosterlitz +3 more
semanticscholar +1 more source
Journal of Neuroscience, 2002 The endogenous opioid system is often assumed to play a role in vulnerability to drug abuse. However, controversial results have been reported regarding the levels of enkephalins or preproenkephalin in neurons of rodent brains after opiate administration.
M. Nieto +4 more
semanticscholar +1 more source
Chemistry – A European Journal, Accepted Article.The direct radical arylation of tyrosine residues in peptides has been achieved under highly attractive conditions, requiring only the peptide substrate, a 3,4,5‐trifluorophenyldiazonium salt and irradiation with visible light. Being well‐balanced in its reactivity to form strong charge transfer complexes with the phenolic side chain, which are ...
Markus Rolf Heinrich +5 more
wiley +1 more source
Wellcome Open Research, 2018 Background: Functional deletion of the Scn9a (sodium voltage-gated channel alpha subunit 9) gene encoding sodium channel Nav1.7 makes humans and mice pain-free. Opioid signalling contributes to this analgesic state.
Vanessa Pereira +5 more
doaj +1 more source
Marine Drugs, 2022 Antimicrobial peptides (AMPs) are found widespread in nature and possess antimicrobial and immunomodulatory activities. Due to their multifunctional properties, these peptides are a focus of growing body of interest and have been characterized in several
Giacomo Zaccone +15 more
doaj +1 more source
Comparative Study of Multicanonical and Simulated Annealing Algorithms in the Protein Folding Problem [PDF]
, 1994 We compare a few variants of the recently proposed multicanonical method with the well known simulated annealing for the effectiveness in search of the energy global minimum of a biomolecular system. For this we study in detail Met-enkephalin, one of the simplest peptides.
arxiv +1 more source
Rugged Metropolis Sampling with Simultaneous Updating of Two Dynamical Variables [PDF]
Phys. Rev. E 72, 016712 (2005), 2005 The Rugged Metropolis (RM) algorithm is a biased updating scheme, which aims at directly hitting the most likely configurations in a rugged free energy landscape. Details of the one-variable (RM$_1$) implementation of this algorithm are presented. This is followed by an extension to simultaneous updating of two dynamical variables (RM$_2$).
arxiv +1 more source
Bioanalytical applications of immobilized antibodies and enzymes [PDF]
, 2022 Dissertation (Ph.D.)--University of Kansas, Chemistry ...
Hendrickson, Tina L.
core
Enkephalins Are Transported by a Novel Eukaryotic Peptide Uptake System*
Journal of Biological Chemistry, 2000 We have identified an oligopeptide transporter in the yeast Saccharomyces cerevisiae which mediates the uptake of tetra- and pentapeptides, including the endogenous opioids leucine enkephalin (Tyr-Gly-Gly-Phe-Leu) and methionine enkephalin (Tyr-Gly-Gly ...
M. Hauser +4 more
semanticscholar +1 more source
Frontiers in Veterinary Science, 2022 Neuropeptides are secretory peptides characterized by small chains of amino acids linked by peptide bonds. They are majorly found in some mammalian neurons and glial cells, where they modulate a variety of physiological homeostasis.
Jamiu O. Omirinde, Idris A. Azeez
doaj +1 more source