Results 81 to 90 of about 12,769 (228)

A comprehensive review of the pharmacodynamics, pharmacokinetics and clinical effects of the neutral endopeptidase inhibitor racecadotril

Frontiers in Pharmacology, 2012
Racecadotril, via its active metabolite thiorphan, is an inhibitor of the enzyme neutral endopeptidase (NEP, EC 3.4.24.11), thereby increasing exposure to NEP including enkephalins and atrial natriuretic peptide.
Marion eEberlin, Thomas eMück, Martin C Michel   +2 more
doaj   +1 more source

The role of enkephalins in the perioperative period in patients with oropharyngeal cancer

Сибирский онкологический журнал
Postoperative metabolic disorder, namely the development of protein-energy deficiency is one of the challenges in cancer surgery, especially in head and neck surgeries, which are considered the most traumatic. The development of protein-energy deficiency
D. N. Vasiliev, D. E. Kulbakin, E. L. Choynzonov, S. V. Avdeev, A. A. Lee, I. P. Puteev, A. V. Pak, A. V. Kushner   +7 more
doaj   +1 more source

NEUROTROPHIC EFFECTS OF ETIFOXINE

Неврология, нейропсихиатрия, психосоматика, 2016
Higher anxiety results in the decreased levels of various neurotrophic factors and enkephalins and in impaired production of proinflammatory cytokines. The anxiolytic etifoxine is used to treat anxiety states and adjustment disorders. Etifoxine modulates
I. Yu. Torshin, O. A. Gromova, V. A. Semenov, O. A. Limanova, I. V. Gogoleva   +4 more
doaj   +1 more source

Nicotine Effects and the Endogenous Opioid System

Journal of Pharmacological Sciences, 2014
.: Nicotine (NIC) is an exogenous ligand of the nicotinic acetylcholine receptor (nAChR), and it influences various functions in the central nervous system. Systemic administration of NIC elicits the release of endogenous opioids (endorphins, enkephalins,
Shiroh Kishioka, Norikazu Kiguchi, Yuka Kobayashi, Fumihiro Saika   +3 more
doaj   +1 more source

THE EFFECT OF INTRACEREBROVENTRICULAR ADMINISTRATION OF METHIONINE‐ENKEPHALIN ON THE STRESS‐INDUCED SECRETION OF CORTICOSTERONE IN MICE [PDF]

, 1979
A Gibson, M. Ginsburg, M Hall, Stephen L. Hart   +3 more
openalex   +1 more source

Enkephalin- and somatostatin-like immunoreactivities in human adrenal medulla and pheochromocytoma. [PDF]

, 1979
Jan M. Lundberg, Bertil Hamberger, Marianne Schultzberg, T Hökfelt, P. O. Granberg, Suad Efendić, Lars Terenius, Menek Goldstein, Roger L. Luft   +8 more
openalex   +1 more source

Asthma and enkephalin. [PDF]

BMJ, 1980
R J Butland, J. Pang, D Geddes
openaire   +3 more sources

Nuclear‐Magnetic‐Resonance Study on Met‐enkephalin and Met‐enkephalin [PDF]

, 1979
Tsutomu Higashijima, Jun’ichi Kobayashi, Ukon Nagai, Tatsuo Miyazawa   +3 more
openalex   +1 more source

Comprehensive review on neprilysin (NEP) inhibitors: design, structure-activity relationships, and clinical applications

Frontiers in Pharmacology
Neprilysin (NEP), a zinc-dependent membrane-bound metallopeptidase, regulates various bioactive peptides, particularly in kidneys, vascular endothelium, and the central nervous system.
Xinyue Zhang, Chun Hu, Erkang Tian, Yanxin Shen, Wei Liu, Juan Li   +5 more
doaj   +1 more source

PHARMACOLOGICAL AND ELECTROPHYSIOLOGICAL STUDIES OF MORPHINE AND ENKEPHALIN ON RAT SUPRASPINAL NEURONES AND CAT SPINAL NEURONES [PDF]

, 1978
J. Davies, A. Dray
openalex   +1 more source