Results 81 to 90 of about 405 (144)

Resistance to antimicrobials [PDF]

La resistència als antimicrobians és una amenaça greu per a la salut pública, reconeguda com una emergència mundial. Tot i ser eclipsada per la pandèmia de la COVID-19, continua sent un problema crucial, amb milions de morts anuals per infeccions ...
González-López, Juan José, Larrosa, Nieves, Puigsech-Boixeda, Guillem   +2 more
core   +2 more sources

Beta-lactamase inhibitors - an effective way to combat antibiotic resistance [PDF]

Introducere. Creşterea rezistenţei microbilor la antibiotice constituie o problemă de sănătate publică. Una din cauzele majore ale rezistenţei la beta-lactamine s-a raportat a fi producerea de beta-lactamaze.
Lehevici, Ion
core  

Restricted Rotational Flexibility of the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase [PDF]

Carbapenem antibiotics are used as a last-resort treatment for infections caused by multidrug-resistant bacteria. The wide spread of carbapenemases in Gram-negative bacteria has severely compromised the utility of these drugs and represents a serious ...
Beer, Michael, Buynak, John, Quan, Pojun, Smith, Clyde, Stewart, Nichole, Toth, Marta, Vakulenko, Sergei   +6 more
core   +2 more sources

Emergence of eravacycline heteroresistance in carbapenem-resistant Acinetobacter baumannii isolates in China [PDF]

Carbapenem-resistant Acinetobacter baumannii (CRAB) is resistant to almost all antibiotics. Eravacycline, a newer treatment option, has the potential to treat CRAB infections, however, the mechanism by which CRAB isolates develop resistance to ...
Chao Zhuo, Guo-hua He, Jian-bo Xu, Ming-zhen Wang, Shan-wen Lin, Xi-xi Tan, Xian-di Chen, Xiao-hu Wang, Yi-tan Li, Ying-yi Guo, Zhi-wei Lin   +10 more
core   +1 more source

Infecção do trato urinário - uma revisão abrangente sobre as causas e agentes causadores, manifestações clínicas, diagnóstico, tratamento, complicações, prevenção e cuidados pós-tratamento [PDF]

A infecção do trato urinário (ITU) é uma condição comum que ocorre quando bactérias, principalmente a Escherichia coli, invadem o sistema urinário. Essas bactérias podem entrar no trato urinário devido a fatores como relações sexuais, uso de cateteres ou
Barbosa, Géssica, Coelho, Rafael de Melo, Lage, Ana Júlia Cândido, Lima, João Carlos Rios, Vianna, Guilherme Lopes Teixeira   +4 more
core   +1 more source

Activity of cefepime/enmetazobactam against highly multidrug-resistant bacterial isolates recovered from war-associated wounds in Ukraine. [PDF]

JAC Antimicrob Resist
Boral J, Toft N, Baybes AE, Tellapragada C, Nazarchuk O, Fernandez C, Giske C, Riesbeck K.   +7 more
europepmc   +1 more source

<i>In vitro</i> activity of cefepime/zidebactam against <i>Klebsiella pneumoniae</i> carrying <i>bla</i> _KPC variants conferring resistance to ceftazidime/avibactam. [PDF]

JAC Antimicrob Resist
Tascini C, Marshall SH, Bonomo RA, Gaibani P.   +3 more
europepmc   +1 more source

Antibacterial activity of enmetazobactam against <i>Acinetobacter</i> spp.: a molecular dissection of mechanism of action and resistance determinants. [PDF]

Antimicrob Agents Chemother
Báez-Barroso G-A, Rodríguez-Coello A, Vázquez-Ucha JC, López-Argüello S, Outeda-García M, González-Pinto L, García-Pose A, Guijarro-Sánchez P, Alonso-García I, Lence E, González-Bello C, Oliver A, Arca-Suárez J, Moya B, Bou G, Beceiro A, Spanish National Acinetobacter spp. 2020 Study Group.   +16 more
europepmc   +1 more source

Cefepime/enmetazobactam for Gram-negative periprosthetic joint infections? A randomized porcine study on target tissue pharmacokinetics. [PDF]

J Antimicrob Chemother
Nielsen MBD, Mikkelsen MKD, Rasmussen HC, Hvistendahl MA, Lützhøft CH, Slater J, Crocoll C, Poborsky M, Jørgensen NP, Soriano A, Stilling M, Bue M.   +11 more
europepmc   +1 more source

In vitro activity of cefepime/zidebactam against sulbactam/durlobactam-susceptible and -resistant Acinetobacter baumannii clinical isolates. [PDF]

J Antimicrob Chemother
Tascini C, Bianco G, Bonomo RA, Gaibani P.   +3 more
europepmc   +1 more source