Results 131 to 140 of about 1,048 (177)

The structure of enniatins and related antibiotics

Tetrahedron, 1963
Abstract The synthesis of cyclotetradepsipeptides the structure of which has previously been assigned to antibiotics of the enniatin group is described. It was found that these antibiotics cannot be represented by the formulas (I)–(VI).
M M, Shemyakin, Y A, Ovchinnkov, V T, Ivanov, A A, Kiryushkin   +3 more
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Enniatin A1, enniatin B1 and beauvericin on HepG2: Evaluation of toxic effects

Food and Chemical Toxicology, 2015
Hepatotoxicity of three Fusarium mycotoxins, beauvericin (BEA) and two enniatins (ENNs) ENN A1 and ENN B1, in hepatocarcinoma cells (HepG2) were evaluated and compared. Concentrations used were 1.5 and 3 μM at 24, 48 and 72 h for each mycotoxin. Flow cytometry was used to examine enniatins effects on cell proliferation, to characterize the cell cycle ...
Ana, Juan-García, María-José, Ruiz, Guillermina, Font, Lara, Manyes   +3 more
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Investigation of the electrophysiological properties of enniatins

Archives of Biochemistry and Biophysics, 2004
Enniatins are cyclohexadepsipeptides produced by various species of the genus Fusarium, and are known to have ionophoric, antibiotic, and in vitro hypolipidaemic properties. With the patch clamp technique in the inside-out mode it could be shown that enniatin easily incorporates into the cell membrane in which it forms cation-selective pores.
Kamyar, Majid-Reza, Rawnduzi, Pakiza, Studenik, Christian, Kouri, Katerina, Lemmens, Rosa   +4 more
openaire   +3 more sources

Synthesis of enniatin B

Experientia, 1963
Die Struktur von Enniatin B, eines antimikrobiellen Wirkstoffes aus Fusarienstammen (ETH, Zurich), wird durch Synthese als die eines Cyclohexapeptolids bewiesen (vgl. X).
Pl. A. Plattner, K. Vogler, R. O. Studer, P. Quitt, W. Keller-Schierlein   +4 more
openaire   +1 more source

Study of locomotion response and development in zebrafish (Danio rerio) embryos and larvae exposed to enniatin A, enniatin B, and beauvericin

Science of The Total Environment, 2021
Mycotoxins are secondary metabolites produced by a variety of fungi that contaminate food and feed resources, and are capable of inducing a wide range of toxicity. Here, we studied the developmental and behavioral toxicity in zebrafish (Danio rerio) embryos and larvae exposed to three mycotoxins: beauvericin (BEA), Enniatin A (ENN A), and Ennitain B ...
Ana, Juan-García, Cristina, Juan, Marie-Abèle, Bind, Florian, Engert   +3 more
openaire   +2 more sources

Beauvericin and enniatin: emerging toxins and/or remedies?

World Mycotoxin Journal, 2010
Beauvericin (BEA) and enniatins (ENN) are emerging Fusarium mycotoxins that are known to contaminate food and feed. BEA- and ENN-mediated cytotoxicity towards various mammalian and cancer cell lines is only partly understood yet and engages several cellular targets and molecular mechanisms.
Tedjiotsop Feudjio, Flora, Dornetshuber-Fleiss, Rita, Lemmens, Marc, Hoffmann, Oskar, Lemmens, Rosa, Berger, Walter   +5 more
openaire   +1 more source

The Crystal Structure of Enniatin B

Helvetica Chimica Acta, 1985
AbstractThe X‐ray crystal structure of enniatin B (trigonal (hexagonal axes), a = 14.626 Å, c = 16.309 Å, space group R3) is described and the conformation compared to results of other investigations.
Christoph Kratky, Max Dobler
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Mechanism of depsipeptide formation catalyzed by enniatin synthetase

Biochemical and Biophysical Research Communications, 1983
Covalently bound intermediates of enniatin B synthesis could be isolated from enniatin synthetase by treatment with performic acid. By comparison with products of mild alkaline cleavage of authentic enniatin B they could be identified as the dipeptide D-2-hydroxyisovaleryl-N-methylvaline and the corresponding tetrapeptide.
R, Zocher, U, Keller, H, Kleinkauf
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A molecular orbital study on the conformation of enniatin B

Biochemical and Biophysical Research Communications, 1973
Abstract Molecular orbital calculations using the PCILO method are performed on the conformation of the symmetrical form of enniatin B. The values of the Φ and ψ angles found for the preferred conformation agree closely with the results of X-ray study of the K + complex of enniatin B.
B, Maigret, B, Pullman
openaire   +2 more sources

THE ENNIATIN IONOPHORES. CONFORMATION AND ION BINDING PROPERTIES

International Journal of Peptide and Protein Research, 1974
The ability of enniatins to bind alkali metal, alkaline earth metal and certain transition metal ions in solution has been investigated. The complexes have been shown to form in 1:1, 2:1 and 3:2 macrocycle:cation ratios; their stability constants have been determined, and the conditions favoring their formation have been established. The enniatins were
Y A, Ovchinnikov, V T, Ivanov, A V, Evstratov, I I, Mikhaleva, V F, Bystrov, S L, Portnova, T A, Balashova, E N, Meshcheryakova, V M, Tulchinsky   +8 more
openaire   +2 more sources