Strangers in the night:a comparative study on the socio-legal difficulties of importing America’s Bayh-Dole legislation to South African universities [PDF]
In 2008, the South African parliament passed the Intellectual Property Rights from Publicly Financed Research and Development Act, which came into effect on 2 August 2010.
Kouletakis, Jade
core
Telbivudine versus entecavir in patients with undetectable hepatitis B virus DNA: a randomized trial. [PDF]
Background: Telbivudine has been suggested to induce hepatitis B surface antigen (HBsAg) decline to the similar degree as pegylated interferon. We aimed to investigate whether telbivudine could further decrease HBsAg titer in patients who maintain ...
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Chronic hepatitis B and hematological malignancies
The active usage of monoclonal antibodies in therapy for hematology malignancies made reactivation of hepatitis B virus (HBV) infection one of the major health problems. Monoclonal antibodies are also used in solid tumors, rheumatic, gastroenterological,
A. O. Buyeverov, P. O. Bogomolov
doaj +1 more source
De novo entecavir+adefovir dipivoxil+lamivudine triple-resistance mutations resulting from sequential therapy with adefovir dipivoxil, and lamivudine [PDF]
Additional file 4: Figure S3. Electropherogram of rtM204 V+rtL180 M+rtA181 V+rtI169 V clone in Patient 3 (GenBank accession number: KU751729)
Huichun Xing +5 more
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Baseline HBV DNA level is the most important factor associated with virologic breakthrough in chronic hepatitis B treated with lamivudine. [PDF]
Aim: To identify the factors associated with virologic breakthrough and to select a subgroup of patients who respond well to lamivudine without developing virologic breakthrough (VBT).
Chae, Hee Bok, Hann, Hie-Won
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HBV quasispecies composition in Lamivudine-failed chronic hepatitis B patients and its influence on virological response to Tenofovir-based rescue therapy [PDF]
The present study sought to evaluate the structure of HBV quasispecies in Lamivudine (LMV)-failed chronic hepatitis B (CHB) patients and its impact in defining the subsequent virological responses to Tenofovir (TDF)-based rescue-therapy. By analyzing HBV
A Ciancio +38 more
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Entecavir (ETV) is an antiviral used to treat chronic infection caused by the hepatitis B virus, which affects approximately 250 million people worldwide.
Cléssius Ribeiro de Souza +7 more
doaj +1 more source
Antivirais incorporados no Brasil para hepatite B cronica: analise de custo-efetividade
OBJETIVO Avaliar o custo-efetividade de diferentes tratamentos medicamentosos para hepatite B crônica entre pacientes adultos. MÉTODOS Utilizando modelo de Markov, construiu-se coorte hipotética de 40 anos para pacientes HBeAg-positivo ou HBeAg ...
Gustavo Laine Araujo de Oliveira +6 more
doaj +1 more source
Impacto de la utilización de hígados de donantes anti-HBc positivo en pacientes trasplantados por hepatitis B [PDF]
El nostre objectiu és avaluar l'impacte de la utilització de fetges de donants anti-HBc positius en pacients trasplantats per hepatitis B, els quals van ser revisats de manera retrospectiva.
García Eliz, Marcia +4 more
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Cost-effectiveness of non-invasive methods for assessment and monitoring of liver fibrosis and cirrhosis in patients with chronic liver disease: systematic review and economic evaluation [PDF]
BACKGROUND: Liver biopsy is the reference standard for diagnosing the extent of fibrosis in chronic liver disease; however, it is invasive, with the potential for serious complications.
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