Results 51 to 60 of about 27,397 (239)

Fosfomycin resistance mechanisms in Enterobacterales: an increasing threat

Frontiers in Cellular and Infection Microbiology, 2023
Antimicrobial resistance is well-known to be a global health and development threat. Due to the decrease of effective antimicrobials, re-evaluation in clinical practice of old antibiotics, as fosfomycin (FOS), have been necessary. FOS is a phosphonic acid derivate that regained interest in clinical practice for the treatment of complicated infection by
Vittoria Mattioni Marchetti, Vittoria Mattioni Marchetti, Vittoria Mattioni Marchetti, Jaroslav Hrabak, Jaroslav Hrabak, Ibrahim Bitar, Ibrahim Bitar   +6 more
openaire   +5 more sources

Evaluating Cefiderocol in the Treatment of Multidrug-Resistant Gram-Negative Bacilli: A Review of the Emerging Data

Infection and Drug Resistance, 2020
Daniele Roberto Giacobbe,1,2 Eugenio Ciacco,3 Corrado Girmenia,4 Federico Pea,5,6 Gian Maria Rossolini,7,8 Giovanni Sotgiu,9 Carlo Tascini,10 Mario Tumbarello,11,12 Pierluigi Viale,5,6 Matteo Bassetti1,2 On behalf of the ISGRI-SITA (Italian Study Group ...
Giacobbe DR, Ciacco E, Girmenia C, Pea F, Rossolini GM, Sotgiu G, Tascini C, Tumbarello M, Viale P, Bassetti M   +9 more
doaj  

Necrotizing skin and soft tissue infections in the intensive care unit

, 2020
BACKGROUND: Necrotizing skin and soft-tissue infections (NSTI) are rare but potentially life-threatening and disabling infections that often require intensive care unit admission.
de Prost, Nicolas, De Waele, Jan, Eckmann, Christian, Norrby-Teglund, Anna, Peetermans, Marijke, Skrede, Steinar   +5 more
core   +2 more sources

Perioperative Piperacillin/Tazobactam Reduces Early Onset SSI in Preirradiated Patients Undergoing Microvascular Head and Neck Reconstruction

Head &Neck, EarlyView.
ABSTRACT Background Preirradiated patients undergoing microvascular head and neck reconstruction for tumor recurrence or osteoradionecrosis (ORN) face surgical site infection (SSI) rates exceeding 30%. The impact of perioperative extended‐spectrum antibiotic coverage remains unclear. This study hypothesizes that calculated prophylaxis with piperacillin/
Johannes G. Schuderer, Florian Hoferer, Jonas Eichberger, Mathias Fiedler, André Gessner, Stilla Bauernfeind, Maximilian Gottsauner, Felix Nieberle, Michael Maurer, Johannes K. Meier, Torsten E. Reichert, Tobias Ettl   +11 more
wiley   +1 more source

Chloramphenicol activity against carbapenemase producing Enterobacterales

Journal of Global Antimicrobial Resistance
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Camarlinghi, Giulio, Parisio, Eva Maria, Antonelli, Alberto, Coppi, Marco, Niccolai, Claudia, Giani, Tommaso, Rossolini, Gian Maria   +6 more
openaire   +3 more sources

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

The world-wide spread of carbapenem-resistant Enterobacterales

One Health & Risk Management, 2020
Introduction. Gram-negative bacilli belonging to the order Enterobacterales are normal inhabitants of the human gut, which also are the most common causative agents of both nosocomial and community-acquired infections in patients of all ages.  Although not even a century has passed since Fleming's discovery of penicillin, the scientists have been ...
Tambic Andrasevic, A., Antal Antunovic, I.   +1 more
openaire   +4 more sources

Ceftolozane/Tazobactam Activity Against Drug-Resistant Pseudomonas aeruginosa and Enterobacterales Causing Healthcare-Associated Infections in Eight Asian Countries: Report from an Antimicrobial Surveillance Program (2016–2018)

Infection and Drug Resistance, 2022
Michael Pfaller,1,2 Dee Shortridge,1 Wei-Ting Chen,3 Helio Sader,1 Mariana Castanheira1 1JMI Laboratories, North Liberty, IA, USA; 2University of Iowa College of Medicine, Iowa City, IA, USA; 3Merck & Co., Inc, Kenilworth, NJ, USACorrespondence: Dee ...
Pfaller M, Shortridge D, Chen WT, Sader H, Castanheira M   +4 more
doaj  

Antimicrobial resistance in Enterobacterales bacilli isolated from bloodstream infection in surgical patients of Polish hospitals [PDF]

, 2021
Background and Aims. Bloodstream infections (BSIs) are one of the most frequently observed hospital-acquired infections (HAIs). We sought to describe the epidemiology and drug resistance secondary Enterobacterales BSIs in surgical patients and check for ...
Chmielarczyk, Agnieszka, Kłos, Marta, Pomorska-Wesołowska, Monika, Romaniszyn, Dorota, Wójkowska-Mach, Jadwiga   +4 more
core   +1 more source

Evaluation of FilmArray Multiplex PCR Test Results in Bloodstream Infections in Oncological Patients

Journal of Clinical Laboratory Analysis, EarlyView.
In this study conducted at an oncology hospital, BCID2 panel results for the rapid identification of microorganisms and resistance genes in positive blood culture samples were compared with conventional culture methods. The BCID2 panel provided faster results and showed a high correlation with traditional methods.
İpek Mumcuoğlu, Sevgi Şahin, Esra Tavukcu, Neşe İnan, Ayşe Semra Güreser, Serap Süzük Yıldız, Tuba Dal   +6 more
wiley   +1 more source