Results 51 to 60 of about 24,289 (229)
British Journal of Clinical Pharmacology, EarlyView.Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu +7 more
wiley +1 more source
Colistin Resistance in Enterobacterales Strains – A Current View [PDF]
Polish Journal of Microbiology, 2019 Abstract Colistin is a member of cationic polypeptide antibiotics known as polymyxins. It is widely used in animal husbandry, plant cultivation, animal and human medicine and is increasingly used as one of the last available treatment options for patients with severe infections with carbapenem-resistant Gram ...
Stefaniuk, Elżbieta, Stefan Tyski
openaire +3 more sources
The diversity and evolution of phenazine biosynthesis pathways in Enterobacterales [PDF]
, 2021 Enterobacterales is an order of Gram-negative bacteria that encompasses plant and animal pathogens and organisms of industrial importance. Some of these bacteria produce secondary metabolites classified as phenazines (Phz).
Leise, Christian
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Infection and Drug Resistance, 2022 Michael Pfaller,1,2 Dee Shortridge,1 Wei-Ting Chen,3 Helio Sader,1 Mariana Castanheira1 1JMI Laboratories, North Liberty, IA, USA; 2University of Iowa College of Medicine, Iowa City, IA, USA; 3Merck & Co., Inc, Kenilworth, NJ, USACorrespondence: Dee ...
Pfaller M +4 more
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Cefepime exposure in prolonged or intermittent infusion in critically ill children
British Journal of Clinical Pharmacology, EarlyView.Aims Cefepime is commonly used in critically ill children for whom there is a high between‐subject variability. To reach the therapeutic pharmacokinetic (PK) target in critically ill patients, prolonged infusion of beta‐lactams seems to be the most efficient.
Marc Hobeika +12 more
wiley +1 more source
iLABMED, EarlyView.ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley +1 more source
Biomedical and Biotechnology Research Journal, 2023 Rise in carbapenem-resistant Gram-negative bacterial infections, especially among immunocompromised patients in healthcare settings is an imminent threat as they are difficult to treat and result in a prolonged length of hospital stay, frequent treatment
Mohan Bilikallahalli Sannathimmappa
doaj +1 more source
Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance
Medicinal Research Reviews, EarlyView.ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi +4 more
wiley +1 more source
Activity of mecillinam against carbapenem-resistant Enterobacterales
Journal of Antimicrobial Chemotherapy, 2022 Abstract Background Despite the fact that carbapenem-resistant Enterobacterales (CRE) mostly cause urinary tract infections (UTIs), only few studies have focused on the efficacity of mecillinam against these CRE.
Emeraud, Cécile +9 more
openaire +3 more sources
Therapeutic Options for Metallo-β-Lactamase-Producing Enterobacterales [Corrigendum]
Infection and Drug Resistance, 2021 Tan X, Kim HS, Baugh K, et al. Infect Drug Resist.2021;14:125–142. Page 134, left column, second paragraph, fourth sentence from the bottom, the text “Generally, all four tetracyclines have higher tissue concentrations than ...
Tan X +8 more
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