Results 51 to 60 of about 25,328 (236)

Incidence of hospital-acquired infections due to carbapenem-resistant Enterobacterales and Pseudomonas aeruginosa in critically ill patients in Italy: a multicentre prospective cohort study

Critical Care
Carbapenem-Resistant Gram-Negative Bacteria, including Carbapenem-Resistant Enterobacterales (CRE) and Carbapenem-Resistant Pseudomonas aeruginosa (CRPA), are common causes of infections in intensive care units (ICUs) in Italy.
G. De Pascale, A. Cortegiani, M. Rinaldi, Massimo Antonelli, S. Cattaneo, Maurizio Cecconi, Raffaele Cuffaro, L. Dalfino, Filomena Di Biase, A. Donati, Francesca Romana Fasano, T. Fasciana, G. Foti, A. Frattari, R. Fumagalli, M. Girardis, Leonardo Gottin, Alessia Mattei, M. Milazzo, G. Montrucchio, Daniela Pasero, F. Picciafuochi, E. Sensi, Giuseppe Servillo, Maria Alejandra Vidal Pereira, T. Spanu, P. Viale, Salvatore Lucio Eloisa Sofia Simone Luca Antonino Romina Erm Cutuli Tanzarella Carelli Montini Giarratano Aceto, S. Cutuli, E. Tanzarella, S. Carelli, L. Montini, A. Giarratano, R. Aceto, E. Casari, Luca Brazzi, A. Curtoni, L. Serio, Filippo Ferrari, V. Savini, Matteo Taiana, A. Mazzariol, S. Ambretti, Grazia Merola, Linda Degl’Innocenti, Renato Ricciardi, Giovanni Gherardi, F. Guerrero, C. Vismara, Elena Vittorielli, E. Casarotta, Maria Vargas, R. Rona, Annalisa Cavallero, Angela Muroni, Salvatore Rubino, B. Viaggi, Tommaso Giani, M. Ippolito, B. Tiri, S. Cappanera, A. Mariottini, Monica Stufano, A. Mosca, Giacomo Monti, Fabio Buffoli   +65 more
semanticscholar   +1 more source

Global prevalence of cefiderocol non-susceptibility in Enterobacterales, Pseudomonas aeruginosa, Acinetobacter baumannii and Stenotrophomonas maltophilia: a systematic review and meta-analysis.

Clinical Microbiology and Infection, 2023
BACKGROUND Cefiderocol is a last resort option for carbapenem-resistant (CR) Gram-negative bacteria, especially metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa and CR Acinetobacter baumannii.
Stamatis Karakonstantis, Maria Rousaki, Loukia Vassilopoulou, Evangelos I. Kritsotakis   +3 more
semanticscholar   +1 more source

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source

Ceftolozane/Tazobactam Activity Against Drug-Resistant Pseudomonas aeruginosa and Enterobacterales Causing Healthcare-Associated Infections in Eight Asian Countries: Report from an Antimicrobial Surveillance Program (2016–2018)

Infection and Drug Resistance, 2022
Michael Pfaller,1,2 Dee Shortridge,1 Wei-Ting Chen,3 Helio Sader,1 Mariana Castanheira1 1JMI Laboratories, North Liberty, IA, USA; 2University of Iowa College of Medicine, Iowa City, IA, USA; 3Merck & Co., Inc, Kenilworth, NJ, USACorrespondence: Dee ...
Pfaller M, Shortridge D, Chen WT, Sader H, Castanheira M   +4 more
doaj  

Relationship between continuous infusion meropenem PK/PD target attainment and C‐reactive protein dynamics in onco‐haematologic patients with febrile neutropenia

British Journal of Clinical Pharmacology, EarlyView.
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu, Pier Giorgio Cojutti, J. G. Coen van Hasselt, Michele Bartoletti, Maddalena Giannella, Pierluigi Zinzani, Pierluigi Viale, Federico Pea   +7 more
wiley   +1 more source

Antimicrobial-resistant Enterobacterales colonization in people with HIV

JAC-Antimicrobial Resistance, 2022
Abstract Background People with HIV (PWH) may be at increased risk for MDR Enterobacterales (MDR-E) infection or colonization, relative to individuals without HIV, due to a greater burden of comorbidities as well as HIV-related intestinal inflammation and microbiota alterations.
Heather I Henderson, Laura Ruegsegger, Kevin Alby, Jason R Smedberg, Bravada M Hill, Dylan Brown, David A Wohl, Sonia Napravnik, David Van Duin   +8 more
openaire   +2 more sources

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Global escalation in carbapenem-resistant Enterobacterales and carbapenem-resistant Acinetobacter baumannii infections: Serious threat to human health from the pink corner

Biomedical and Biotechnology Research Journal, 2023
Rise in carbapenem-resistant Gram-negative bacterial infections, especially among immunocompromised patients in healthcare settings is an imminent threat as they are difficult to treat and result in a prolonged length of hospital stay, frequent treatment
Mohan Bilikallahalli Sannathimmappa
doaj   +1 more source

Evaluation of MicroScan and VITEK 2 systems for susceptibility testing of Enterobacterales with updated breakpoints

Journal of Clinical Microbiology
We compared the performance of two commercial antimicrobial susceptibility testing (AST) systems for contemporary Enterobacterales strains using broth microdilution (BMD) as the reference standard with 2022 Clinical and Laboratory Standards Institute or ...
Sandra S. Richter, Elizabeth L. Dominguez, Aaron A. Hupp, M. Griffis, Shawn H. MacVane   +4 more
semanticscholar   +1 more source

Gut microbiota shifts and short‐chain fatty acids alterations in pediatric epilepsy patients on a Mediterranean ketogenic diet

Epileptic Disorders, EarlyView.
Abstract Objective The olive oil–based Mediterranean ketogenic diet (MedKD) may support patients with drug‐resistant epilepsy (DRE) or neurometabolic disorders by integrating ketogenic therapy with the cardiometabolic and neuroprotective advantages of the Mediterranean diet.
Sofia Zouganeli, Evdokia K. Mitsou, Mary Yannakoulia, Evangelia Intze, Konstantinos C. Mountzouris, Smaragdi Fessatou, Achilleas Attilakos, Adamantini Kyriacou, Argyrios Dinopoulos   +8 more
wiley   +1 more source