Results 71 to 80 of about 28,778 (289)

Chain‐Length Regulation by WzzE Is Necessary for, but Genetically Separable From, Cyclic Enterobacterial Common Antigen Synthesis

Molecular Microbiology, EarlyView.
Here, we demonstrate that polysaccharide chain length regulation plays a distinct role in enabling formation of a cyclic molecule important for the bacterial cell surface. However, this function is necessary, but not sufficient for the cyclic molecule's biosynthesis.
Joseph F. Carr, Yohannes H. Rezenom, Jennifer S. Rudolf, Daniel J. Warzecha, Angela M. Mitchell   +4 more
wiley   +1 more source

Preclinical evaluation of 2-[18F]fluorodeoxysorbitol as a tracer for targeted imaging of Enterobacterales infection [PDF]

, 2023
Fluorine-18-fluorodeoxyglucose ([18F]FDG) positron emission tomography (18F-FDG-PET) is widely used for the detection of inflammatory and infectious diseases.
Jan Maarten van Dijl, Boersma, Hendrikus H., Riemer H.J.A. Slart, Slart, Riemer H J A, van Oosten, Marleen, Sijbesma, Jürgen W A; id_orcid, van Dijl, Jan Maarten, Sijbesma, Jürgen W A, Boersma, Hendrikus H, Lisanne M. Braams, Hendrikus H. Boersma, Philip H. Elsinga, Elsinga, Philip H, Elsinga, Philip H., Glaudemans, Andor W J M, Glaudemans, Andor W.J.M., Glaudemans, Andor W J M; id_orcid, Boersma, Hendrikus H; id_orcid, Marleen van Oosten, Andor W.J.M. Glaudemans, Braams, Lisanne M., Sijbesma, Jürgen W.A., Jürgen W.A. Sijbesma, Slart, Riemer H.J.A., Braams, Lisanne M   +24 more
core   +1 more source

Serious Bacterial Infections in Hospitalized Neonates in Eastern Ethiopia: Investigating the Emerging Pathogen Pantoea dispersa Compared With Klebsiella pneumoniae

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Serious bacterial infections (SBIs) are major contributors to neonatal morbidity and mortality in low‐income countries. We describe the aetiology and risk factors for neonatal bacteraemia and in‐hospital mortality in eastern Ethiopia, focusing on Pantoea dispersa, a rarely studied pathogen, and Klebsiella pneumoniae.
Yunus Edris, Faisel A. Hassen, Desalegn A. Ayana, Fami Ahmed, Haleluya Leulseged, Dadi Marami, Jabir Aliye, Belete G. Alem, Zelalem T. Mariam, Gezahang Mengesha, Nega Assefa, Alexander M. Aiken, J. Anthony G. Scott, Lola Madrid   +13 more
wiley   +1 more source

Infections Caused by Carbapenem-Resistant Enterobacterales: Epidemiology, Clinical Significance, and Possibilities for Antibiotic Therapy Optimization

Антибиотики и Химиотерапия, 2020
The resistance of Enterobacterales to carbapenems can be realized by different mechanisms, but the most common one is enzymatic, associated with the production of carbapenemases.
S. V. Yakovlev, M. P. Suvorova, A. O. Bykov   +2 more
doaj   +1 more source

Identification of a Novel Ceftazidime-Avibactam-Resistant KPC-2 Variant, KPC-123, in Citrobacter koseri Following Ceftazidime-Avibactam Treatment

Frontiers in Microbiology, 2022
This study reported the identification of a novel ceftazidime-avibactam-resistant KPC-2 variant, KPC-123, in a Citrobacter koseri isolated from a patient in a Chinese hospital following ceftazidime-avibactam treatment of infection caused by OXA-232 ...
Lin Wang, Weiyi Shen, Rong Zhang, Jiachang Cai   +3 more
doaj   +1 more source

Molecular epidemiology of β-lactamases in ceftriaxone-resistant Enterobacterales bloodstream infections in the mid-Atlantic United States

Antimicrobial Agents and Chemotherapy
Ceftriaxone-resistant Enterobacterales remain a public health threat; contemporary data investigating their molecular epidemiology are limited. Five hundred consecutive ceftriaxone-resistant (MIC ≥ 4 µg/mL) Enterobacterales bloodstream isolates were ...
Dariusz A. Hareza, Yehudit Bergman, Emily B Jacobs, Jennifer Lu, N. Hanson, Rick Conzemius, Sara E. Cosgrove, Anthony D. Harris, P. Simner, P. Tamma   +9 more
semanticscholar   +1 more source

Assessment of the efficacy of large volume delayed sampling primary culture and pathogen reduction in preventing septic reactions from platelet transfusions

Transfusion, EarlyView.
Abstract Background Many mitigation processes have been introduced to reduce septic transfusion reactions (STRs) caused by the transfusion of bacterially contaminated PLTs. Methods The efficacy of primary culture and pathogen reduction is assessed in this review using data from long‐term hemovigilance programs in the US, Canada, UK, France, Switzerland,
Michael R. Jacobs
wiley   +1 more source

Carbapenem- and cefiderocol-resistant Enterobacterales in surface water in Kumasi, Ashanti Region, Ghana [PDF]

Background: MDR pathogens including ESBL- and/or carbapenemase-producing Enterobacterales (ESBL-PE and CPE) increasingly occur worldwide in the One Health context.
Eger, Elias, Adade, Eugene, Knauf, Sascha, Dreyer, Sylvia, Lübcke, Phillip, Homeier-Bachmann, Timo, Heiden, Stefan E., Sylverken, Augustina A, Schaufler, Katharina, Tawiah, Patrick O.   +9 more
core   +1 more source

Rapid detection of KPC-producing Enterobacterales by using a modified Carba NP test with imipenem/relebactam.

, 2022
20.500.12530/87858Here, we propose a novel modified Carba NP test for detecting KPC-producing Enterobacterales using imipenem/relebactam. The test performance was evaluated in a random selection of 160 previously molecularly characterized clinical ...
González-Bardanca, Mónica, Candela, Ana, Ramírez, Cecilia de la Luna, Oviaño, Marina, Bou, Germán   +4 more
core   +1 more source

A pilot study of the clinical significance and outcomes of infections in the ICU caused by colistin-resistant Klebsiella pneumoniae

Вестник анестезиологии и реаниматологии
The objective was to study the risk factors, outcomes of infections caused by colistin-resistant K. pneumonia (CRKP) and to evaluate the  sensitivity of these microorganisms to antibacterial agents to determine the most adequate antibiotic therapy ...
I. N. Sychev, O. V. Ignatenko, S. V. Yakovlev, L. V. Fedina, E. N. Burmistrova, M. P. Suvorova, T. D. Rastvorova, E. V. Strigunkova, R. Kh. Mukhamadiev   +8 more
doaj   +1 more source