Results 81 to 90 of about 28,778 (289)

Antibiotic Treatment of Infections Caused by AmpC-Producing Enterobacterales

Pharmacy
AmpC enzymes are a class of beta-lactamases produced by Gram-negative bacteria, including several Enterobacterales. When produced in sufficient amounts, AmpCs can hydrolyze third-generation cephalosporins (3GCs) and piperacillin/tazobactam, causing ...
G. Tebano, Irene Zaghi, M. Cricca, Francesco Cristini   +3 more
semanticscholar   +1 more source

Role of Gram‐Negative Bacterial Infections in Acute‐On‐Chronic Liver Failure

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Acute‐on‐chronic liver failure (ACLF) is a systemic disease characterised by an acute clinical deterioration of pre‐existing liver cirrhosis leading to multiple organ failure due to systemic inflammation. It may be triggered by the translocation of bacteria and bacterial compounds across the gut barrier.
Camilla Cadoli, Volker Müller, Christoph Welsch, Heiko Mühl, Jonel Trebicka, Volkhard A. J. Kempf   +5 more
wiley   +1 more source

Rapid detection of KPC-producing Enterobacterales by using a modified Carba NP test with imipenem/relebactam.

, 2021
20.500.12530/87858Here, we propose a novel modified Carba NP test for detecting KPC-producing Enterobacterales using imipenem/relebactam. The test performance was evaluated in a random selection of 160 previously molecularly characterized clinical ...
González-Bardanca, Mónica, Candela, Ana, Ramírez, Cecilia de la Luna, Oviaño, Marina, Bou, Germán   +4 more
core   +1 more source

Difficulties in choosing antibacterial therapy regimen for nosocomial pneumonia in intensive care units: clinical observations [PDF]

Клиническая микробиология и антимикробная химиотерапия
Nosocomial pneumonia is one of the most common healthcare-associated infections and the most frequent in intensive care unit (ICU) patients. The clinical and economic consequences of nosocomial pneumonia are very significant, especially for ventilated ...
Rachina S.A., Fedina L.V., Alkhlavov A.A., Gasanova D.R., Zainalabidova Kh.G., Koval A.A., Burmistrova E.N., Savochkina Yu.A., Sychev I.N., Kuleshov V.G., Larin E.S.   +10 more
doaj   +1 more source

Antibiotics in Veterinary Ophthalmology: Resistance, Stewardship, and Emerging Antibiotic‐Sparing Strategies

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Antimicrobial resistance (AMR) is a growing challenge in veterinary ophthalmology, particularly in cases of bacterial keratitis, where progressive stromal infection can threaten vision and globe integrity within hours to days. This review synthesizes current evidence on pathogen distribution, antimicrobial susceptibility profiles, multidrug ...
Lionel Sebbag, Oren Pe'er
wiley   +1 more source

Antibiotic Resistance Genes Among Carbapenem-resistant Enterobacterales (CRE) Isolates of Prapokklao Hospital, Chanthaburi Province, Thailand

Infection and Drug Resistance, 2021
Witawat Tunyong,1 Weewan Arsheewa,2 Sirijan Santajit,3,4 Thida Kong-ngoen,1 Pornpan Pumirat,1 Nitat Sookrung,5,6 Wanpen Chaicumpa,6 Nitaya Indrawattana1 1Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok,
Tunyong W, Arsheewa W, Santajit S, Kong-ngoen T, Pumirat P, Sookrung N, Chaicumpa W, Indrawattana N   +7 more
doaj  

Antimicrobial resistance of clinical isolates of Klebsiella pneumoniae and Escherichia coli in Russian hospitals: results of a multicenter epidemiological study [PDF]

Клиническая микробиология и антимикробная химиотерапия
Objective. To study the prevalence and mechanisms of antibiotic resistance, including carbapenemase production, in clinical isolates of Klebsiella pneumoniae and Escherichia coli isolated in different regions of Russia as part of the sentinel ...
Edelstein M.V., Shajdullina E.R., Ivanchik N.V., Dekhnich A.V., Mikotina A.V., Skleenova E.Yu., Sukhorukova M.V., Azyzov I.S., Shek E.A., Romanov A.V., Trushin I.S., Kuzmenkov A.Yu., Kozlov R.S.   +12 more
doaj   +1 more source

Evaluation of the activity of cefepime/enmetazobactam against Enterobacterales bacteria collected in Europe from 2019 to 2021, including third-generation cephalosporin-resistant isolates.

Journal of Global Antimicrobial Resistance
OBJECTIVES This study was performed to investigate the activity of the novel ß-lactam/ß-lactamase inhibitor combination cefepime/enmetazobactam, against recently circulating Enterobacterales isolates from Europe in 2019 to 2021.
Ian Morrissey, Stephen Hawser, N. Kothari, N. Dunkel, J. Quevedo, A. Belley, A. S. Henriksen, M. Attwood   +7 more
semanticscholar   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

Screening for Metallo-Beta-Lactamases Using Non-Carbapenem Agents: Effective Detection of MBL-Producing Enterobacterales and Differentiation of Carbapenem-Resistant Enterobacterales

, 2023
Metallo-beta-lactamases (MBLs) are enzymes that break down carbapenem antibiotics, leading to carbapenem-resistant organisms. Carbapenemase-resistant Enterobacterales (CRE) is one of them. Outbreaks of CRE infection can occur in healthcare facilities and
Koichi Tokuda, Chiho Kitamura, Yumiko Takei, Kengo Oshima, Kentarou Takei, Hajime Kanamori, Mikiko Chiba, Asami Nakayama, Issei Seike, Hiroaki Baba   +9 more
core   +1 more source