Results 21 to 30 of about 10,640,678 (241)

Generation of enteroendocrine cell diversity in midgut stem cell lineages. [PDF]

Development, 2015
The endocrine system mediates long-range peptide hormone signaling to broadcast changes in metabolic status to distant target tissues via the circulatory system. In many animals, the diffuse endocrine system of the gut is the largest endocrine tissue, with the full spectrum of endocrine cell subtypes not yet fully characterized.
Beehler-Evans R, Micchelli CA.
europepmc   +4 more sources

Elevated Serum Chromogranin-A and Characteristic Duodenal Enteroendocrine Cell Distribution in Pancreatic Fibrosis and Chronic Pancreatitis Compared with Other Dyspeptic Disorders: A Case Series Study. [PDF]

Diagnostics (Basel)
Huang CT, Liang YJ.
europepmc   +3 more sources

Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation. [PDF]

Cell Stem Cell
Singh PNP, Gu W, Madha S, Lynch AW, Cejas P, He R, Bhattacharya S, Muñoz Gomez M, Oser MG, Brown M, Long HW, Meyer CA, Zhou Q, Shivdasani RA.   +13 more
europepmc   +2 more sources

Single cell transcriptomic profiling of large intestinal enteroendocrine cells in mice – Identification of selective stimuli for insulin-like peptide-5 and glucagon-like peptide-1 co-expressing cells

Molecular Metabolism, 2019
Objective: Enteroendocrine cells (EECs) of the large intestine, found scattered in the epithelial layer, are known to express different hormones, with at least partial co-expression of different hormones in the same cell.
Lawrence J. Billing, Pierre Larraufie, Jo Lewis, Andrew Leiter, Joyce Li, Brian Lam, Giles SH. Yeo, Deborah A. Goldspink, Richard G. Kay, Fiona M. Gribble, Frank Reimann   +10 more
doaj   +2 more sources

Intestinal Enteroendocrine Cells: Present and Future Druggable Targets [PDF]

International Journal of Molecular Sciences, 2023
Enteroendocrine cells are specialized secretory lineage cells in the small and large intestines that secrete hormones and peptides in response to luminal contents. The various hormones and peptides can act upon neighboring cells and as part of the endocrine system, circulate systemically via immune cells and the enteric nervous system.
Roger Atanga, Varsha Singh, Julie In
openalex   +3 more sources

Quantitation and chemical coding of enteroendocrine cell populations in the human jejunum. [PDF]

Cell Tissue Res, 2020
Fazio Coles TE, Fothergill LJ, Hunne B, Nikfarjam M, Testro A, Callaghan B, McQuade RM, Furness JB.   +7 more
europepmc   +2 more sources

Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals

Scientific Reports, 2017
Morbidly obese patients exhibit impaired secretion of gut hormones that may contribute to the development of obesity. After bariatric surgery there is a dramatic increase in gut hormone release.
Bettina K. Wölnerhanssen, Andrew W. Moran, Galina Burdyga, Anne Christin Meyer‐Gerspach, Ralph Peterli, Markus G. Manz, Miriam Thumshirn, Kristian Daly, Christoph Beglinger, Soraya P. Shirazi‐Beechey   +9 more
openalex   +2 more sources

Enteroendocrine Cell [PDF]

Definitions, 2020

semanticscholar   +2 more sources

Microbial Control of Intestinal Homeostasis via Enteroendocrine Cell Innate Immune Signaling. [PDF]

Trends Microbiol, 2020
Watnick PI, Jugder BE.
europepmc   +2 more sources

Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion [PDF]

Proceedings of the National Academy of Sciences, 2019
Significance The stem cell niche is the in vivo microenvironment in which stem cells both reside and receive stimuli that determine their fate. Intestinal Paneth cells produce an arsenal of molecules involved in numerous biological processes, including ...
J. van Es, K. Wiebrands, C. López-Iglesias, M. van de Wetering, L. Zeinstra, Maaike van den Born, J. Korving, Nobuo Sasaki, P. Peters, A. van Oudenaarden, H. Clevers   +10 more
semanticscholar   +6 more sources