Results 101 to 110 of about 21,092 (255)

Biology of the microbiome 2: metabolic role [PDF]

, 2017
The human microbiome is a new frontier in biology and one that is helping to define what it is to be human. Recently, we have begun to understand that the "communication" between the host and its microbiome is via a metabolic superhighway.
Li, Jia V., Marchesi, Julian Roberto, Swann, Jonathan   +2 more
core   +2 more sources

Review Article: Targeting Peroxisome Proliferator‐Activated Receptors in Primary Biliary Cholangitis

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 9, Page 1215-1235, May 2026.
Peroxisome proliferator‐activated receptor (PPAR) agonists have emerged as important second‐line treatments in primary biliary cholangitis, with profiles influenced by different selectivity for α‐, δ‐ and γ‐isoforms. PPAR‐α and PPAR‐δ agonism improve cholestasis, with inflammation reduced via all isoforms. PPAR‐δ agonism also reduces pruritus.
Jörn M. Schattenberg, Jesus M. Banales, Gideon Hirschfield, Palak Trivedi, Edward E. Cable, Charles A. McWherter, Andrew N. Billin, Daria B. Crittenden, Grant Budas   +8 more
wiley   +1 more source

ДИСЛИПИДЕМИЯ И АССОЦИИРОВАНЫЕ МЕТАБОЛИЧЕСКИЕ ЗАБОЛЕВАНИЯ

Архивъ внутренней медицины, 2011
This article presents the pathogenesis of dyslipidemia and associated metabolic disorders with the position of lipid metabolism. The role of natural mechanism of cholesterol homeostasis changing was showed, functional disorders of the enterohepatic ...
О. Ш. Ойноткинова, Е. И. Дедов   +1 more
doaj   +1 more source

Liver transplantation: a life-saving procedure following amatoxin mushroom poisoning [PDF]

, 2017
published_or_final_versio
CK Chan, CM Lo, FL Lau, Kenneth SH Chok, KW Ma, null null, SC Chan, SL Sin, WC Dai   +8 more
core   +1 more source

The proteomic differences and expression of fatty acid‐binding protein 6 (FABP6) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone

Equine Veterinary Journal, Volume 58, Issue 3, Page 845-856, May 2026.
Abstract Background Phenylbutazone (PBZ) can potentially induce gastrointestinal ulceration, and early detection of PBZ‐induced gastroenteropathy will be useful for the diagnosis, treatment, and prevention of PBZ toxicity. Objectives To identify putative proteins associated with equine gastric ulcer syndrome after clinical dose (4.4 mg/kg ...
Ruethaiwan Vinijkumthorn, Nawarus Prapaiwan, Thanapon Chotikaprakal, Phirom Prompiram, Narumon Phaonakrop, Sittiruk Roytrakul, Parichart Tesena   +6 more
wiley   +1 more source

Analysis of gut microecological characteristics and differences between children with biliary atresia and non-biliary atresia in infantile cholestasis

Frontiers in Cellular and Infection Microbiology
IntroductionIn infants with cholestasis, variations in the enterohepatic circulation of bile acids and the gut microbiota (GM) characteristics differ between those with biliary atresia (BA) and non-BA, prompting a differential analysis of their ...
Yajun Liu, Yuan Zhang, Cheng Guo, Muxia Li, Ye Wang, Lin Zhang   +5 more
doaj   +1 more source

7α-Hydroxylation of cholestanol by rat liver microsomes

Journal of Lipid Research, 1968
In a study of the mechanism whereby 5α-bile acids are formed from cholestanol, the 7α-hydroxylation of cholestanol was investigated in rat liver preparations in vitro.
Sarah Shefer, Susan Hauser, Erwin H. Mosbach   +2 more
doaj   +1 more source

High cholesterol absorption efficiency interferes with bile acid metabolism and cholesterol elimination from the body

Journal of Internal Medicine, Volume 299, Issue 5, Page 628-638, May 2026.
Abstract Background Elevated low‐density lipoprotein (LDL) cholesterol causes atherosclerotic cardiovascular diseases. Variables of whole‐body cholesterol metabolism, for example, high cholesterol absorption efficiency, might also be atherogenic, whereas the role of bile acids is controversial.
Piia Simonen, Ingmar Wester, Jyri Lommi, Juha Sinisalo, Helena Gylling   +4 more
wiley   +1 more source

Decision letter for "Investigate dysregulated lipid metabolism in diabetic mice via targeted metabolomics of bile acids in enterohepatic circulation"

, 2021

openalex   +2 more sources

Effects of amoxicillin/clavulanic acid on the pharmacokinetics of valproic acid

Drug Design, Development and Therapy, 2015
Soo-Yun Lee,1 Wooseong Huh,2 Jin Ah Jung,3 Hye Min Yoo,2 Jae-Wook Ko,1,2 Jung-Ryul Kim2,4 1Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, 2Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, 
Lee SY, Huh W, Jung JA, Yoo HM, Ko JW, Kim JR   +5 more
doaj