Results 91 to 100 of about 21,092 (255)

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1309-1325, May 2026.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source

Mathematically modelling the dynamics of cholesterol metabolism and ageing [PDF]

, 2016
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the UK. This conditionbecomes increasingly prevalent during ageing; 34.1% and 29.8% of males and females respectively, over 75years of age have an underlying cardiovascular ...
A.E. Morgan, Abbott, Ajouz, Al-Sheraji, Anandaraja, Appelman, Atzel, Atzel, Atzmon, Austin, Baigent, Baptissart, Barter, Barzilai, Batta, Begley, Berard, Bertolotti, Bertolotti, Bhattacharya, Boone, Brown, Chang, Chapman, Chirackal Manavalan, Cooney, Cooper, Cui, Demirezen, Duan, Dujovne, Ericsson, Field, Fu, Gerard, Gillotte, Guo, He, He, Hennessy, Herron, Hollander, Hoops, Hopkins, Hopkins, Hovingh, Hubner, Hucka, Hucka, Ikeda, Iqbal, Jansen, Jarocki, Jerby, Ji, Jia, Jones, Jones, Juty, K.M. Mooney, Kersten, Kervizic, Le Novère, Li, Lichtenstein, Lin, Liscum, Lu, Lund-Katz, M.T. Mc Auley, Marino, Mazein, Mc Auley, Mc Auley, Mc Auley, Mc Auley, Mc Auley, McAuley, McNamara, Micheloni, Millan, Millar, Mishra, Mooney, Mooney, Morgan, Moro-Garcia, N.A. Pickles, Ohashi, Ohtani, Olivecrona, Parini, Patsch, Petersen, Prince, Quintao, Rohn, S.J. Wilkinson, Scheibner, Sharma, Shorten, Sips, Sorci-Thomas, Spady, Tanaka, Tannock, Trautwein, Tuohy, Uchida, van de Pas, Wang, Watterson, WHO, Woollett, Yang, Zhang, Zhong   +116 more
core   +3 more sources

Nutrition in necrotizing enterocolitis and following intestinal resection [PDF]

, 2020
This review aims to discuss the role of nutrition and feeding practices in necrotizing enterocolitis (NEC), NEC prevention, and its complications, including surgical treatment.
Courtney, Cathleen M, Ou, Jocelyn, Steinberger, Allie E, Tecos, Maria E, Warner, Brad W   +4 more
core   +2 more sources

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Microbiota Modification with Probiotics Induces Hepatic Bile Acid Synthesis via Downregulation of the Fxr-Fgf15 Axis in Mice

Cell Reports, 2014
Gut microbiota influences host health status by providing trophic, protective, and metabolic functions, including bile acid (BA) biotransformation.
Chiara Degirolamo, Stefania Rainaldi, Fabiola Bovenga, Stefania Murzilli, Antonio Moschetta   +4 more
doaj   +1 more source

Curcumin Nanoformulations for Dermatological Applications: From Nutraceuticals to Nanocarriers

Food Frontiers, Volume 7, Issue 3, May 2026.
Nanotechnology‐based delivery platforms enhance the cutaneous administration of curcumin. Loading free curcumin into polymeric micelles, metal‐based nanoparticles, nanogels/hydrogels, liposomes, polymeric nanoparticles, or nanoemulsions/nanocrystals helps address its low solubility, poor stability and limited skin permeation. As a result, these systems
Stephany Celeste Gutiérrez‐Ruiz, Alejandra Romero‐Montero, Hector Hernández‐Parra, Sheila I. Peña‐Corona, Héctor Adrián García‐Gasca, Katya Carbone, Fabio Gervasi, Shivaprasad Shetty Mangalpady, Rajesh Kaverikana, Mariia Shanaida, Volodymyr Shanaida, Daniela Calina, Javad Sharifi‐Rad, Gerardo Leyva‐Gómez   +13 more
wiley   +1 more source

Epidemiology, Risk Factors and Pathophysiology of Primary Sclerosing Cholangitis in Inflammatory Bowel Disease: An Update

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) represent a unique clinical syndrome affecting up to 80% of PSC patients, characterised by distinct epidemiological patterns, pathophysiological mechanisms and clinical outcomes that differ substantially from either condition occurring independently ...
Luisa Bertin, Paul Henderson, Richard Pollok, Natália Queiroz, Luca Fabris, Edoardo Vincenzo Savarino, Iago Rodríguez‐Lago, Brigida Barberio   +7 more
wiley   +1 more source

Bile Acids Conjugation in Human Bile Is Not Random: New Insights from 1H-NMR Spectroscopy at 800 MHz [PDF]

, 2009
Bile acids constitute a group of structurally closely related molecules and represent the most abundant constituents of human bile. Investigations of bile acids have garnered increased interest owing to their recently discovered additional biological ...
Cooper, Amanda, Maluccio, Mary, Nagana Gowda, G. A., Raftery, Daniel, Shanaiah, Narasimhamurthy   +4 more
core   +1 more source

Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 5, May 2026.
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu, Wenqing Qin, Minghang Dong, Zhi Ma, Si Li, Runping Liu, Ranyun Chen, Changmeng Li, Xiaojiaoyang Li   +8 more
wiley   +1 more source

Quantitative analysis of unconjugated and conjugated bile acids in duodenal fluid by densitometry after paper electrophoresis

Journal of Lipid Research, 1973
A new paper electrophoretic method for the separation of bile acids into five groups, (1) unconjugated, (2) glycine conjugates and (3) taurine conjugates, and (4) and (5) the respective monosulfates, is described.
Neil Kaplowitz, Norman B. Javitt
doaj   +1 more source