Results 91 to 100 of about 13,632 (184)

Gut microbiota derived DCA enhances FOLFOX efficacy via Ugt1a6b mediated enterohepatic circulation in colon cancer

Pharmacological Research
FOLFOX (5-Fluorouracil, Calcium Folinate combined with Oxaliplatin) is a preferred chemotherapy regimen for colon cancer, but its limited efficacy remains a major challenge, significantly impairs patient outcomes.
Qian Fang, Xiaoying Hou, Limei Fan, Yufei Deng, Xiaoxuan Li, Hongyun Zhang, Haiping Wang, Zhengqi Fu, Binlian Sun, Xiji Shu, Hongzhi Du, Yuchen Liu   +11 more
doaj   +1 more source

ENTEROHEPATIC CIRCULATION OF PRACTOLOL IN MAN [PDF]

British Journal of Clinical Pharmacology, 1974
C M, Kaye, C R, Kumana
openaire   +2 more sources

INTESTINAL MECHANISMS OF ENTEROHEPATIC CIRCULATION DISTURBANCE OF BILE ACIDS IN CHOLELITHIASIS

, 2017
Background: Cholelithiasis is one of the most common diseases of the digestive system which affects all segments of the population and preserves a stable growth of incidence rates.
I. A. Penkina, Ya. M. Vakhrushev, A. P. Lukashevich, A. Yu. Gorbunov   +3 more
core   +1 more source

Chorioamnionitis induces hepatic inflammation and time-dependent changes of the enterohepatic circulation in the ovine fetus. [PDF]

Sci Rep, 2021
Heymans C, den Dulk M, Lenaerts K, Heij LR, de Lange IH, Hadfoune M, van Heugten C, Kramer BW, Jobe AH, Saito M, Kemp MW, Wolfs TGAM, van Gemert WG.   +12 more
europepmc   +1 more source

Determination of Bile Acids in Canine Biological Samples: Diagnostic Significance

Metabolites
The comprehensive examination of bile acids is of paramount importance across various fields of health sciences, influencing physiology, microbiology, internal medicine, and pharmacology.
Krisztián Németh, Ágnes Sterczer, Dávid Sándor Kiss, Réka Katalin Lányi, Vivien Hemző, Kriszta Vámos, Tibor Bartha, Anna Buzás, Katalin Lányi   +8 more
doaj   +1 more source

Features of bile acid metabolism in fish and their biological significance (review)

Аграрная наука Евро-Северо-Востока
Bile acids in fish, as in other vertebrates, represent a complex metabolic system the composition of which depends on species, age, diet, and environmental conditions. Their ratio is closely associated with enterohepatic circulation—a continuous cycle of
A. V. Prusakov, M. S. Golodyaeva, V. S. Ponamarev   +2 more
doaj   +1 more source

Transcription factor Klf9 controls bile acid reabsorption and enterohepatic circulation in mice via promoting intestinal Asbt expression. [PDF]

Acta Pharmacol Sin, 2022
Liu S, Liu M, Zhang ML, Wang CZ, Zhang YL, Zhang YJ, Du CY, Sheng SF, Wang W, Fan YT, Song JN, Huang JC, Feng YY, Qiao W, Huang JL, Li YH, Zhou L, Zhang J, Chang YS.   +18 more
europepmc   +1 more source

Enterohepatic bile-acid circulation in the pregnant cat

, 1988
Pregnancy increases the risk of gallstones. The physiological changes responsible for this are not clearly demonstrated. Adjustments in the enterohepatic circulation of bile acids have earlier been studied in pregnancy by methods involving dilution of ...
Svanvik, J, Samsioe, G, Friman, Styrbjörn,, Rådberg, Göran,   +3 more
core  

Acute effects of HMG-COA reductase inhibitors on biliary lipids in patients with interrupted enterohepatic circulation.

, 1991
HMG-CoA reductase inhibitors decrease serum cholesterol by inhibiting hepatic cholesterol synthesis, but their influence on biliary lipids is not well characterized.
LISE, MARIO, GABELLI C., MURACA, MAURIZIO, MICONI L., BELLUCO, CLAUDIO, CREPALDI G., MARTINI S., VILEI M. T., BAGGIO G.   +8 more
core  

ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity

Chinese Medicine
Background Atherosclerosis (AS) is the most common cardiovascular disease (CVD), despite an overall declining incidence, AS remains a leading cause of death worldwide. The ZeXieYin formula (ZXYF), one of the thirteen formulas recorded in HuangDiNeiJin, a
Shihan Zhou, Shangbo Hua, Xinyi Chen, Meiling Ni, Jing Liu, Yanqing Wang, Wanning Wu, Anni Ding, Zizhen Qin, Xinyu Yang, Xiaowei Chen, Boran Zhu, Haoxin Wu   +12 more
doaj   +1 more source