Results 71 to 80 of about 13,632 (184)

Neurotensin elevates hepatic bile acid secretion in chickens by a mechanism requiring an intact enterohepatic circulation

, 2000
Neurotensin (NT), given intravenously at 10-50 pmol/kg per min to anesthetized female chickens equipped with a bile duct fistula, dose- dependently elevated hepatic bile flow and bile acid output but only when the enterohepatic circulation was maintained
Robert E Carraway, Duke, Gary E, Xianyong Gui, Gary E Duke, Carraway, Robert E, Gui, Xianyong, Degolier, Teresa F, Teresa F DeGolier   +7 more
core   +1 more source

7α-Hydroxylation of cholestanol by rat liver microsomes

Journal of Lipid Research, 1968
In a study of the mechanism whereby 5α-bile acids are formed from cholestanol, the 7α-hydroxylation of cholestanol was investigated in rat liver preparations in vitro.
Sarah Shefer, Susan Hauser, Erwin H. Mosbach   +2 more
doaj   +1 more source

Effects of amoxicillin/clavulanic acid on the pharmacokinetics of valproic acid

Drug Design, Development and Therapy, 2015
Soo-Yun Lee,1 Wooseong Huh,2 Jin Ah Jung,3 Hye Min Yoo,2 Jae-Wook Ko,1,2 Jung-Ryul Kim2,4 1Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, 2Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, 
Lee SY, Huh W, Jung JA, Yoo HM, Ko JW, Kim JR   +5 more
doaj  

Development of Population PK Model with Enterohepatic Circulation for Mycophenolic Acid in Patients with Childhood-Onset Systemic Lupus Erythematosus

, 2012
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Despite its increased use, the pharmacokinetics (PK) of mycophenolic acid (MPA) and the relationship between dose, plasma concentration and exposure are poorly understood, especially in children. • The PK of MPA
Brunner, Hermine I., Anna Carmela P. Sagcal-Gironella, Sherwin, Catherine M.T., Sagcal-Gironella, Anna Carmela P., Hermine I. Brunner, Tsuyoshi Fukuda, Catherine M. T. Sherwin, Vinks, Alexander A., Fukuda, Tsuyoshi, Alexander A. Vinks   +9 more
core   +1 more source

Quantifying Forms and Functions of Enterohepatic Bile Acid Pools in MiceSummary

Cellular and Molecular Gastroenterology and Hepatology
Backgrounds & Aims: Bile acids (BAs) are core gastrointestinal metabolites with dual functions in lipid absorption and cell signaling. BAs circulate between the liver and distal small intestine (i.e., ileum), yet the dynamics through which complex BA
Koichi Sudo, Amber Delmas-Eliason, Shannon Soucy, Kaitlyn E. Barrack, Jiabao Liu, Akshaya Balasubramanian, Chengyi Jenny Shu, Michael J. James, Courtney L. Hegner, Henry D. Dionne, Alex Rodriguez-Palacios, Henry M. Krause, George A. O’Toole, Saul J. Karpen, Paul A. Dawson, Daniel Schultz, Mark S. Sundrud   +16 more
doaj   +1 more source

Withaferin-A down-regulate enterohepatic circulation of bile acids: An insight from a hyperlipidemic rat model.

, 2020
Hyperlipidemia is a metabolic abnormality in both young and aged populations across the world. Withaferin-A (WT) present in Withania somnifera (Indian ginseng) has been studied by many investigators for their therapeutic potentials.
Parvati, H., Pooja, Acharya, Sadashivaiah, B., Vinayak, Uppin, Ramaprasad, T. R., Mehrdad, Zarei, Nayana, Venugopal   +6 more
core   +1 more source

Bile acid transporters

Journal of Lipid Research, 2009
In liver and intestine, transporters play a critical role in maintaining the enterohepatic circulation and bile acid homeostasis. Over the past two decades, there has been significant progress toward identifying the individual membrane transporters and ...
Paul A. Dawson, Tian Lan, Anuradha Rao
doaj   +1 more source

CCK-8 infusion increases plasma LMW alkaline phosphatase coincident with enterohepatic circulation of bile acids

, 1997
Bile acids may facilitate the release of liver alkaline phosphatase (ALP) from its hydrophobic membrane anchor. The purpose of this study was to determine whether such a facilitatory role could be observed during the enterohepatic circulation of bile ...
W. E. Hoffmann, D. J. Schaeffer, P. F. Solter, M. D. Chambers   +3 more
core   +1 more source

Cyclosporin A and enterohepatic circulation of bile salts in rats: Decreased cholate synthesis but increased intestinal reabsorption

, 2003
Cyclosporin A (CsA) has been shown to inhibit synthesis and hepatobiliary transport of bile salts. However, effects of CsA on the enterohepatic circulation of bile salts in vivo are largely unknown.
Kuipers, F; id_orcid, Hulzebos, CV, Stellaard, F, Plosch, T; id_orcid, Wolters, H, Sauer, PJJ, Kuipers, F, Stengelin, S, Verkade, HJ, Plosch, T, Verkade, HJ; id_orcid   +10 more
core   +1 more source

Enterohepatic circulation of scymnol sulfate in an elasmobranch, the little skate (Raja erinacea)

, 1997
The sulfated bile alcohol scymnol sulfate (ScyS), 3α,7α,12α,24ξ,26,27-hexahydroxy-5β-cholestane-26(27)-sulfate, is the major bile salt in bile of an elasmobranch, the little skate.
Ruth Fricker, James L. Boyer, Ralph Wössner, Gert Fricker, Jürgen Drewe   +4 more
core   +1 more source